An Integrated Web-based System for MEDLINE Analysis: A Case Study of Chronic Kidney Disease

In the era of big data, medical researchers attempt to utilize some analysis techniques like machine learning and text mining on their large-scale corpora to save valuable labor work and time. Consequently, many data analysis platforms are built to support medical professionals such as Pubtator, GeneWays, BioContext, etc. These platforms are helpful to medical entities recognition and relation extraction, but there is not an integrated platform to support researchers’ various needs, and medical projects are isolated from each other, which is hard to be shared and reused. As a result, we present an integrated system containing ‘name entity recognition’, ‘document categorization’ and ‘association extraction’. Besides, we add the concept of ‘socialization’ making projects reusable for further analyses. A case study of chronic kidney disease was adopted to indicate the effectiveness of the proposed system

TiFi: Taxonomy Induction for Fictional Domains [Extended version]

Taxonomies are important building blocks of structured knowledge bases, and their construction from text sources and Wikipedia has received much attention. In this paper we focus on the construction of taxonomies for fictional domains, using noisy category systems from fan wikis or text extraction as input. Such fictional domains are archetypes of entity universes that are poorly covered by Wikipedia, such as also enterprise-specific knowledge bases or highly specialized verticals. Our fiction-targeted approach, called TiFi, consists of three phases: (i) category cleaning, by identifying candidate categories that truly represent classes in the domain of interest, (ii) edge cleaning, by selecting subcategory relationships that correspond to class subsumption, and (iii) top-level construction, by mapping classes onto a subset of high-level WordNet categories. A comprehensive evaluation shows that TiFi is able to construct taxonomies for a diverse range of fictional domains such as Lord of the Rings, The Simpsons or Greek Mythology with very high precision and that it outperforms state-of-the-art baselines for taxonomy induction by a substantial margin

Information Extraction in Illicit Domains

Extracting useful entities and attribute values from illicit domains such as human trafficking is a challenging problem with the potential for widespread social impact. Such domains employ atypical language models, have `long tails' and suffer from the problem of concept drift. In this paper, we propose a lightweight, feature-agnostic Information Extraction (IE) paradigm specifically designed for such domains. Our approach uses raw, unlabeled text from an initial corpus, and a few (12-120) seed annotations per domain-specific attribute, to learn robust IE models for unobserved pages and websites. Empirically, we demonstrate that our approach can outperform feature-centric Conditional Random Field baselines by over 18\% F-Measure on five annotated sets of real-world human trafficking datasets in both low-supervision and high-supervision settings. We also show that our approach is demonstrably robust to concept drift, and can be efficiently bootstrapped even in a serial computing environment.Comment: 10 pages, ACM WWW 201

Knowledge-based methods for automatic extraction of domain-specific ontologies

Semantic web technology aims at developing methodologies for representing large amount of knowledge in web accessible form. The semantics of knowledge should be easy to interpret and understand by computer programs, so that sharing and utilizing knowledge across the Web would be possible. Domain specific ontologies form the basis for knowledge representation in the semantic web. Research on automated development of ontologies from texts has become increasingly important because manual construction of ontologies is labor intensive and costly, and, at the same time, large amount of texts for individual domains is already available in electronic form. However, automatic extraction of domain specific ontologies is challenging due to the unstructured nature of texts and inherent semantic ambiguities in natural language. Moreover, the large size of texts to be processed renders full-fledged natural language processing methods infeasible. In this dissertation, we develop a set of knowledge-based techniques for automatic extraction of ontological components (concepts, taxonomic and non-taxonomic relations) from domain texts. The proposed methods combine information retrieval metrics, lexical knowledge-base(like WordNet), machine learning techniques, heuristics, and statistical approaches to meet the challenge of the task. These methods are domain-independent and automatic approaches. For extraction of concepts, the proposed WNSCA+{PE, POP} method utilizes the lexical knowledge base WordNet to improve precision and recall over the traditional information retrieval metrics. A WordNet-based approach, the compound term heuristic, and a supervised learning approach are developed for taxonomy extraction. We also developed a weighted word-sense disambiguation method for use with the WordNet-based approach. An unsupervised approach using log-likelihood ratios is proposed for extracting non-taxonomic relations. Further more, a supervised approach is investigated to learn the semantic constraints for identifying relations from prepositional phrases. The proposed methods are validated by experiments with the Electronic Voting and the Tender Offers, Mergers, and Acquisitions domain corpus. Experimental results and comparisons with some existing approaches clearly indicate the superiority of our methods. In summary, a good combination of information retrieval, lexical knowledge base, statistics and machine learning methods in this study has led to the techniques efficient and effective for extracting ontological components automatically

Taxonomy Induction using Hypernym Subsequences

We propose a novel, semi-supervised approach towards domain taxonomy induction from an input vocabulary of seed terms. Unlike all previous approaches, which typically extract direct hypernym edges for terms, our approach utilizes a novel probabilistic framework to extract hypernym subsequences. Taxonomy induction from extracted subsequences is cast as an instance of the minimumcost flow problem on a carefully designed directed graph. Through experiments, we demonstrate that our approach outperforms stateof- the-art taxonomy induction approaches across four languages. Importantly, we also show that our approach is robust to the presence of noise in the input vocabulary. To the best of our knowledge, no previous approaches have been empirically proven to manifest noise-robustness in the input vocabulary

Designing algorithms to aid discovery by chemical robots

Recently, automated robotic systems have become very efficient, thanks to improved coupling between sensor systems and algorithms, of which the latter have been gaining significance thanks to the increase in computing power over the past few decades. However, intelligent automated chemistry platforms for discovery orientated tasks need to be able to cope with the unknown, which is a profoundly hard problem. In this Outlook, we describe how recent advances in the design and application of algorithms, coupled with the increased amount of chemical data available, and automation and control systems may allow more productive chemical research and the development of chemical robots able to target discovery. This is shown through examples of workflow and data processing with automation and control, and through the use of both well-used and cutting-edge algorithms illustrated using recent studies in chemistry. Finally, several algorithms are presented in relation to chemical robots and chemical intelligence for knowledge discovery