Development and Experimental Analysis of Wireless High Accuracy Ultra-Wideband Localization Systems for Indoor Medical Applications

This dissertation addresses several interesting and relevant problems in the field of wireless technologies applied to medical applications and specifically problems related to ultra-wideband high accuracy localization for use in the operating room. This research is cross disciplinary in nature and fundamentally builds upon microwave engineering, software engineering, systems engineering, and biomedical engineering. A good portion of this work has been published in peer reviewed microwave engineering and biomedical engineering conferences and journals. Wireless technologies in medicine are discussed with focus on ultra-wideband positioning in orthopedic surgical navigation. Characterization of the operating room as a medium for ultra-wideband signal transmission helps define system design requirements. A discussion of the first generation positioning system provides a context for understanding the overall system architecture of the second generation ultra-wideband positioning system outlined in this dissertation. A system-level simulation framework provides a method for rapid prototyping of ultra-wideband positioning systems which takes into account all facets of the system (analog, digital, channel, experimental setup). This provides a robust framework for optimizing overall system design in realistic propagation environments. A practical approach is taken to outline the development of the second generation ultra-wideband positioning system which includes an integrated tag design and real-time dynamic tracking of multiple tags. The tag and receiver designs are outlined as well as receiver-side digital signal processing, system-level design support for multi-tag tracking, and potential error sources observed in dynamic experiments including phase center error, clock jitter and drift, and geometric position dilution of precision. An experimental analysis of the multi-tag positioning system provides insight into overall system performance including the main sources of error. A five base station experiment shows the potential of redundant base stations in improving overall dynamic accuracy. Finally, the system performance in low signal-to-noise ratio and non-line-of-sight environments is analyzed by focusing on receiver-side digitally-implemented ranging algorithms including leading-edge detection and peak detection. These technologies are aimed at use in next-generation medical systems with many applications including surgical navigation, wireless telemetry, medical asset tracking, and in vivo wireless sensors

Massive MIMO-based Localization and Mapping Exploiting Phase Information of Multipath Components

In this paper, we present a robust multipath-based localization and mapping framework that exploits the phases of specular multipath components (MPCs) using a massive multiple-input multiple-output (MIMO) array at the base station. Utilizing the phase information related to the propagation distances of the MPCs enables the possibility of localization with extraordinary accuracy even with limited bandwidth. The specular MPC parameters along with the parameters of the noise and the dense multipath component (DMC) are tracked using an extended Kalman filter (EKF), which enables to preserve the distance-related phase changes of the MPC complex amplitudes. The DMC comprises all non-resolvable MPCs, which occur due to finite measurement aperture. The estimation of the DMC parameters enhances the estimation quality of the specular MPCs and therefore also the quality of localization and mapping. The estimated MPC propagation distances are subsequently used as input to a distance-based localization and mapping algorithm. This algorithm does not need prior knowledge about the surrounding environment and base station position. The performance is demonstrated with real radio-channel measurements using an antenna array with 128 ports at the base station side and a standard cellular signal bandwidth of 40 MHz. The results show that high accuracy localization is possible even with such a low bandwidth.Comment: 14 pages (two columns), 13 figures. This work has been submitted to the IEEE Transaction on Wireless Communications for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessibl

The Future of the Operating Room: Surgical Preplanning and Navigation using High Accuracy Ultra-Wideband Positioning and Advanced Bone Measurement

This dissertation embodies the diversity and creativity of my research, of which much has been peer-reviewed, published in archival quality journals, and presented nationally and internationally. Portions of the work described herein have been published in the fields of image processing, forensic anthropology, physical anthropology, biomedical engineering, clinical orthopedics, and microwave engineering. The problem studied is primarily that of developing the tools and technologies for a next-generation surgical navigation system. The discussion focuses on the underlying technologies of a novel microwave positioning subsystem and a bone analysis subsystem. The methodologies behind each of these technologies are presented in the context of the overall system with the salient results helping to elucidate the difficult facets of the problem. The microwave positioning system is currently the highest accuracy wireless ultra-wideband positioning system that can be found in the literature. The challenges in producing a system with these capabilities are many, and the research and development in solving these problems should further the art of high accuracy pulse-based positioning

Performance of Bit Error Rate and Power Spectral Density of Ultra Wideband with Time Hopping Sequences.

This thesis focuses on several modulation methods for an ultra wideband (UWB) signal. These methods are pulse position modulation (PPM), binary phase shift keying (BPSK), on/off key shifting (OOK), and pulse amplitude modulation (PAM). In addition, time hopping is considered for these modulation schemes, where the capacity per time frame of time hopping PPM is studied using different spreading ratios. This thesis proves that with the addition of time hopping to all types of modulated UWB signals, the performance of power spectral density improves in all aspects, despite the increase of data per time frame. Note that despite the increase of data per frame, the bit error rate remains the same as standard non-time hopping UWB modulated signals

A Hybrid Indoor Location Positioning System

Indoor location positioning techniques have experienced impressive growth in recent years. A wide range of indoor positioning algorithms has been developed for various applications. In this work a practical indoor location positioning technique is presented which utilizes off-the-shelf smartphones and low-cost Bluetooth Low Energy (BLE) nodes without any further infrastructure. The method includes coarse and fine modes of location positioning. In the coarse mode, the received signal strength (RSS) of the BLE nodes is used for location estimation while in the fine acoustic signals are utilized for accurate positioning. The system can achieve centimeter-level positioning accuracy in its fine mode. To enhance the system’s performance in noisy environments, two digital signal processing (DSP) algorithms of (a) band-pass filtering with audio pattern recognition and (b) linear frequency modulated chirp signal with matched filter are implemented. To increase the system’s robustness in dense multipath environments, a method using data clustering with sliding window is employed. The received signal strength of BLE nodes is used as an auxiliary positioning method to identify the non-line-of-sight (NLoS) propagation paths in the acoustic positioning mode. Experimental measurement results in an indoor area of 10 m2 indicate that the positioning error falls below 6 cm

CIR Parametric Rules Precocity For Ranging Error Mitigation In IR-UWB

The cutting-edge technology to support high ranging accuracy within the indoor environment is Impulse Radio Ultra Wide Band (IR-UWB) standard. Besides accuracy, IR-UWB’s low-complex architecture and low power consumption align well with mobile devices. A prime challenge in indoor IR-UWB based localization is to achieve a position accuracy under non-line-of-sight (NLOS) and multipath propagation (MPP) conditions. Another challenge is to achieve acceptable accuracy in the conditions mentioned above without any significant increase in latency and computational burden. This dissertation proposes a solution for addressing the accuracy and reliability problem of indoor localization system satisfying acceptable delay or computational complexity overhead. The proposed methodology is based on rules for identification of line-of-sight (LOS) and NLOS and the range error bias estimation and correction due to NLOS and MPP conditions. The proposed methodology provides accuracy for two major application domains, namely, wireless sensor networks (WSNs) and indoor tracking and navigation (ITN). This dissertation offers two different solutions for the localization problem. The first solution is a rules-based classification of LOS / NLOS and geometric-based range correction for WSN. In the first solution, the Boolean logic based classification is designed for identification of LOS/NLOS. The logic is based on channel impulse response (CIR) parameters. The second solution is based on fuzzy logic. The fuzzy based solution is appealing well for the stringent precision requirements in ITN. In this solution, the parametric Boolean logic from the first solution is converted and expanded into rules. These rules are implemented into a fuzzy logic based mechanism for designing a fuzzy inference system. The system estimates the ranging errors and correcting unmitigated ranges. The expanded rules and designed methodology are based on theoretical analysis and empirical observations of the parameters. The rules accommodate the parameters uncertainties for estimating the ranging error through the relationship between the input parameters uncertainties and ranging error using fuzzy inference mechanism. The proposed solutions are evaluated using real-world measurements in different indoor environments. The performance of the proposed solutions is also evaluated in terms of true classification rate, residual ranging errors’ cumulative distributions and probability density distributions, as well as outage probabilities. Evaluation results show that the true classification rate is more than 95%. Moreover, using the proposed fuzzy logic based solution, the residual errors convergence of 90% is attained for error threshold of 10 cm, and the reliability of the localization system is also more than 90% for error threshold of 15 cm