686,525 research outputs found

    Igloos all year round: an examination of the views of young people into spaces and places in Douglas

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    This research was carried out in collaboration with Douglas Matters as part of a Community Academic Research Links (CARL) project. Douglas Matters is a community group that was set up to tackle the presenting issues for young people in the area. This dissertation examined the views and of young people into spaces and places in Douglas, through the use of primary, qualitative research. Photo-voice and individual interviews were used to gain an insight into the views and issues of concern of young people in the area. Secondary research, namely a literature review, explored the concept of spaces and places, recreation and the positive effects it had on young people, and community responses to children in need. Theories examined in the literature review allowed for an understanding to be gained when looking at the perception of young people in Douglas and how they interact with their environment. A significant finding of this research identified the lack of services for young people in the area, which in turn has led to feelings of boredom and exclusion. The research also found that adults perceived young people in a negative light, which has led to young people being excluded from public spaces. Based on such findings, a number of recommendations have been made which hope to enable Douglas Matters to work from the ground up, to make Douglas a better place to grow up in

    Thirty-Three Stata Tips

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    Since 2003, the Stata Journal has published Stata Tips on special issues in data analysis with Stata. Now Thirty-three Stata Tips compiles these useful guides into a compact tome for ease of reference. In keeping with the Stata spirit, Tips are from Stata users and StataCorp employees alike and will serve as guideposts for both new and experienced users.data management, statistics, graphics, Stata

    Comparison of transjugular intrahepatic portosystemic shunt with covered stent and balloon-occluded retrograde transvenous obliteration in managing isolated gastric varices

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    OBJECTIVE: Although a transjugular intrahepatic portosystemic shunt (TIPS) is commonly placed to manage isolated gastric varices, balloon-occluded retrograde transvenous obliteration (BRTO) has also been used. We compare the long-term outcomes from these procedures based on our institutional experience. MATERIALS AND METHODS: We conducted a retrospective review of patients with isolated gastric varices who underwent either TIPS with a covered stent or BRTO between January 2000 and July 2013. We identified 52 consecutive patients, 27 who had received TIPS with a covered stent and 25 who had received BRTO. We compared procedural complications, re-bleeding rates, and clinical outcomes between the two groups. RESULTS: There were no significant differences in procedural complications between patients who underwent TIPS (7%) and those who underwent BRTO (12%) (p = 0.57). There were also no statistically significant differences in re-bleeding rates from gastric varices between the two groups (TIPS, 7% [2/27]; BRTO, 8% [2/25]; p = 0.94) or in developing new ascites following either procedure (TIPS, 4%; BRTO, 4%; p = 0.96); significantly more patients who underwent TIPS developed hepatic encephalopathy (22%) than did those who underwent BRTO (0%, p = 0.01). There was no statistically significant difference in mean survival between the two groups (TIPS, 30 months; BRTO, 24 months; p = 0.16); median survival for the patients who received TIPS was 16.6 months, and for those who underwent BRTO, it was 26.6 months. CONCLUSION: BRTO is an effective method of treating isolated gastric varices with similar outcomes and complication rates to those of TIPS with a covered stent but with a lower rate of hepatic encephalopathy

    Atomic resolution imaging of electrode surfaces in solutions containing reversible redox species

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    Procedures are described for insulating metal scanning tunneling microscope (STM) tips with either glass or polymer coatings. In solutions containing 0.10 M of a reversible redox couple, Fe(CN) - 3/-46 , the faradaic limiting current to polymer coated tips was 200–500 pA and that for glass coated tips was <10 pA. For polymer insulated tips, steady-state currents of 10–100 pA were observed at tip-sample displacements less than 0.3 µm. The suppression of faradaic current achieved by these coating procedures enabled the collection of the first atomic resolution STM images of highly ordered pyrolytic graphite electrodes in contact with redox-active electrolytes. Preliminary data for the in situ electrochemical characterization of these tips are also discussed

    Programming Safety Tips: Why You Should Use Immutable Objects or How to create programs with bugs that can never be found or fixed.

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    Program safety deals with how to make programs as error free as possible. The hardest errors in a program for a programmer to find are often errors in using memory. There are two reasons for this. The first is that errors in accessing memory almost never show problems in the proximate area of the program where the error is made. The error has no apparent impact when it is made, but often causes catastrophic results to occur much later in the program, in areas of the program unrelated to memory error that caused it. The second reason memory errors are so difficult to find is that the working of memory is often poorly understood by most novice, and many professional, programmers. This makes it difficult for many programmers to even understand why an action causes the error. This article will show an example of a program error that can easily occur when memory access is poorly understood. This leads to program errors that are very easy to fix when they are found, but extremely difficult to find. The article will then explain how many memory errors can be easily avoided by following the very simple rule, “Make all object immutable unless there is a good reason to make them mutable”, and why immutable objects are an essential tool in good, safe programming practice

    Carbon fibre tips for scanning probe microscopy based on quartz tuning fork force sensors

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    We report the fabrication and the characterization of carbon fibre tips for their use in combined scanning tunnelling and force microscopy based on piezoelectric quartz tuning fork force sensors. We find that the use of carbon fibre tips results in a minimum impact on the dynamics of quartz tuning fork force sensors yielding a high quality factor and consequently a high force gradient sensitivity. This high force sensitivity in combination with high electrical conductivity and oxidation resistance of carbon fibre tips make them very convenient for combined and simultaneous scanning tunnelling microscopy and atomic force microscopy measurements. Interestingly, these tips are quite robust against occasionally occurring tip crashes. An electrochemical fabrication procedure to etch the tips is presented that produces a sub-100 nm apex radius in a reproducible way which can yield high resolution images.Comment: 14 pages, 10 figure

    TIPS for the treatment of refractory ascites, hepatorenal syndrome and hepatic hydrothorax: a critical update

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    Refractory ascites is a frequent complication of advanced cirrhosis and is associated with hepatorenal syndrome and hepatic hydrothorax. Large volume paracentesis and pleurodesis are regarded as first-line treatments in patients who do not respond adequately to diuretics. These treatments, however, do not prevent recurrence and carry the risk of worsening of the circulatory dysfunction leading to hepatorenal syndrome. The transjugular intrahepatic portosystemic shunt ( TIPS) has been proposed as an alternative to paracentesis. TIPS reduces the rate of ascites recurrence mainly due to the reduction in the filtration pressure. In addition, TIPS results in a positive effect on renal function, including hepatorenal syndrome, demonstrated by a rapid increase in urinary sodium excretion, urinary volume, and improvement in plasma creatinine concentration. Furthermore, plasma renin activity, aldosterone, and noradrenalin concentrations improve gradually after TIPS insertion suggesting a positive effect on systemic underfilling, the factor of hepatorenal syndrome. As demonstrated recently in two meta-analyses including five randomised studies, TIPS also improves survival when compared with paracentesis. However, the evidence is based on relatively few studies with only 305 patients included. The positive effects of the TIPS are opposed by an increased frequency and severity of episodes of hepatic encephalopathy which may be reduced by both patient selection and reduced shunt diameter. Based on the present knowledge the recommended hierarchy of treatments for refractory ascites may be reconsidered upgrading TIPS in suitable candidates

    Searching atomic spin contrast on nickel oxide (001) by force microscopy

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    The (001) surface of NiO, an antiferromagnet at room temperature, was investigated under ultra-high vacuum conditions with frequency modulation atomic force microscopy (FM-AFM). The antiferromagnetic coupling between ions leads to a spin superstructure on (001) surfaces. Exchange interaction between the probe of a force microscope and the NiO (001) surface should allow to image spin superstructures in real space. The surface was imaged with three different probing tips: nonmagnetic W tips, ferromagnetic Co tips and antiferromagnetic NiO tips - and atomic resolution was achieved with all three of them in various distance regimes and in several channels. Evidence for spin contrast was obtained in experiments that utilize NiO tips and oscillation amplitudes in the \AA-regime, where optimal signal-to-noise ratio is expected. The spin contrast is weaker than expected and only visible in Fourier space images.Comment: 7 pages, 6 figures, submitted to Physical Review
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