463,057 research outputs found
Cellular automaton supercolliders
Gliders in one-dimensional cellular automata are compact groups of
non-quiescent and non-ether patterns (ether represents a periodic background)
translating along automaton lattice. They are cellular-automaton analogous of
localizations or quasi-local collective excitations travelling in a spatially
extended non-linear medium. They can be considered as binary strings or symbols
travelling along a one-dimensional ring, interacting with each other and
changing their states, or symbolic values, as a result of interactions. We
analyse what types of interaction occur between gliders travelling on a
cellular automaton `cyclotron' and build a catalog of the most common
reactions. We demonstrate that collisions between gliders emulate the basic
types of interaction that occur between localizations in non-linear media:
fusion, elastic collision, and soliton-like collision. Computational outcomes
of a swarm of gliders circling on a one-dimensional torus are analysed via
implementation of cyclic tag systems
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Mechanisms underlying extremely fast muscle V˙O2 on-kinetics in humans.
The time constant of the primary phase of pulmonary V˙O2 on-kinetics (τp ), which reflects muscle V˙O2 kinetics during moderate-intensity exercise, is about 30 s in young healthy untrained individuals, while it can be as low as 8 s in endurance-trained athletes. We aimed to determine the intramuscular factors that enable very low values of t0.63 to be achieved (analogous to τp , t0.63 is the time to reach 63% of the V˙O2 amplitude). A computer model of oxidative phosphorylation (OXPHOS) in skeletal muscle was used. Muscle t0.63 was near-linearly proportional to the difference in phosphocreatine (PCr) concentration between rest and work (ΔPCr). Of the two main factors that determine t0.63 , a huge increase in either OXPHOS activity (six- to eightfold) or each-step activation (ESA) of OXPHOS intensity (>3-fold) was needed to reduce muscle t0.63 from the reference value of 29 s (selected to represent young untrained subjects) to below 10 s (observed in athletes) when altered separately. On the other hand, the effect of a simultaneous increase of both OXPHOS activity and ESA intensity required only a twofold elevation of each to decrease t0.63 below 10 s. Of note, the dependence of t0.63 on OXPHOS activity and ESA intensity is hyperbolic, meaning that in trained individuals a large increase in OXPHOS activity and ESA intensity are required to elicit a small reduction in τp . In summary, we postulate that the synergistic action of elevated OXPHOS activity and ESA intensity is responsible for extremely low τp (t0.63 ) observed in highly endurance-trained athletes
A guided tour of asynchronous cellular automata
Research on asynchronous cellular automata has received a great amount of
attention these last years and has turned to a thriving field. We survey the
recent research that has been carried out on this topic and present a wide
state of the art where computing and modelling issues are both represented.Comment: To appear in the Journal of Cellular Automat
A nonmonotone GRASP
A greedy randomized adaptive search procedure (GRASP) is an itera-
tive multistart metaheuristic for difficult combinatorial optimization problems. Each
GRASP iteration consists of two phases: a construction phase, in which a feasible
solution is produced, and a local search phase, in which a local optimum in the
neighborhood of the constructed solution is sought. Repeated applications of the con-
struction procedure yields different starting solutions for the local search and the
best overall solution is kept as the result. The GRASP local search applies iterative
improvement until a locally optimal solution is found. During this phase, starting from
the current solution an improving neighbor solution is accepted and considered as the
new current solution. In this paper, we propose a variant of the GRASP framework that
uses a new “nonmonotone” strategy to explore the neighborhood of the current solu-
tion. We formally state the convergence of the nonmonotone local search to a locally
optimal solution and illustrate the effectiveness of the resulting Nonmonotone GRASP
on three classical hard combinatorial optimization problems: the maximum cut prob-
lem (MAX-CUT), the weighted maximum satisfiability problem (MAX-SAT), and
the quadratic assignment problem (QAP)
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