Collection and processing of data from wrist wearable devices in heterogeneous and multiple-user scenarios

Over recent years, we have witnessed the development of mobile and wearable technologies to collect data from human vital signs and activities. Nowadays, wrist wearables including sensors (e.g., heart rate, accelerometer, pedometer) that provide valuable data are common in market. We are working on the analytic exploitation of this kind of data towards the support of learners and teachers in educational contexts. More precisely, sleep and stress indicators are defined to assist teachers and learners on the regulation of their activities. During this development, we have identified interoperability challenges related to the collection and processing of data from wearable devices. Different vendors adopt specific approaches about the way data can be collected from wearables into third-party systems. This hinders such developments as the one that we are carrying out. This paper contributes to identifying key interoperability issues in this kind of scenario and proposes guidelines to solve them. Taking into account these topics, this work is situated in the context of the standardization activities being carried out in the Internet of Things and Machine to Machine domains.Xunta de Galicia | Ref. GRC2013-00

The Dynamics of Central-Peripheral Stress Responses after Acute Psychosocial Stress: a Multimodal Perspective

An acute stress response is a complex interaction of central and peripheral psychophysiological systems with unique temporal characteristics. Interestingly, the interaction represents a unique temporal characteristic. Investigating the dynamics of both brain and body signals during and after an encounter with a stressor allows us to understand the underlying principle of the acute stress response, which has been shown to be atypical in various psychiatric disorders. However, a detailed understanding of stress response is rarely investigated. Therefore, this thesis investigates two major approaches for understanding the acute stress response dynamics using simultaneous electroencephalography (EEG)-photoplethysmographyfunctional magnetic resonance imaging experiments in 39 subjects before and after the ScanStress task. The EEG-derived vigilance indexes reveal a continuous decline at rest. Given the role of alertness in an efficient stress response, the effects of acute stress induction on EEG-derived vigilance metrics are of interest. Therefore, the first approach uses the dynamic analysis of psychophysiological stress responses after the acute psychosocial stress induction. The first study investigates the carry-over effect of acute psychosocial stress on vigilance and its modulation by the multicomponent over-thecounter drug neurexan, which has been shown to modulate the neuroendocrine stress response. By using dynamic analysis, six vigilance scores were calculated every two minutes before and after the stress induction during the resting state. The study revealed that stress delays the continuous decline of vigilance at rest. In addition, the stress-induced increase in mean vigilance levels at rest was correlated positively with the levels of perceived stress during the last month. In addition, the mean vigilance level exhibited a decrease after neurexan treatment compared to placebo intake. Heart rate variability (HRV) can be viewed as an indicator of how well the adaptive regulation system in the brain reacts the peripheral environment. However, the relationship between the HRV and functional connectivity patterns in the brain networks in stressful situations is rarely investigated. Therefore, the second approach uses the multimodal approach to examine the interaction between different stress response systems. The study investigated the temporal association between HRV and FC between the three core brain networks, namely the central executive network, salience network, and default mode network at baseline and after the psychosocial stress induction. In this study, the functional connectivity between three core brain networks and the HRV was examined by taking 60s window length. Furthermore, the temporal association between HRV and functional connectivity was investigated. A significant association was found between HRV and default mode network-central executive network functional connectivity at rest, which was significantly reduced after acute stress induction compared to baseline. These findings suggest that HRV cofluctuates with the core brain networks selectively depending on the stress conditions. In summary, acute psychological stress affects brain dynamics by exhibiting a delay in the continuously declining vigilance and keeping the brain in a more alert state even after the stressor disappears. Furthermore, the results suggest that EEG-derived vigilance metrics index not only stress-response but also the temporal dynamics of vigilance regulation. It can serve as a potential biomarker for the diagnosis and prognosis for stress-related disorders disrupting temporal characteristics of stress response dynamics and showing atypical stress response. In addition, the study revealed that stress affects the interactions among the core large-scale functional networks and physiological dynamics of the heart. The dynamic adaptation of the resources is crucial in a stressful situation; therefore, the stress alters the interaction between the brain and heart. The perturbation in this interaction may play an important role in developing and maintaining stress-related disorders. The thesis work provides novel insights and an understanding of the central and peripheral stress response dynamics, which show a huge potential for the diagnosis, prognosis, and therapeutic planning of individuals with neuropsychiatric disorders

Green exercise: Combined influence of environment and exercise to promote wellbeing

Exercise participation is linked to mental health and wellbeing. However, we need to identify optimal settings for promoting exercise-associated wellbeing outcomes, and for promoting exercise adherence. The literature suggests environmental settings may be important. The aim of this thesis was to rigorously test influences of environmental settings on exercise-related wellbeing outcomes. These over-arching research questions guided the experimental chapters: (i) is there an optimal green exercise environment for promoting wellbeing? (ii) When exercise is controlled, are findings consistent with previously reported psychological outcomes? (iii) Do environmental settings influence social outcomes of exercise or intentions to repeat exercise behaviours? Via field-based sampling, Chapter 3 found large proportions of affective benefits were universally obtainable across four typical green exercise environments, and suggested that the processes component of green exercise warranted further investigation; however, this method lacked control. Chapter 4 used laboratory-based methodology to control exercise and isolate the visual environment; consistent with both theory and previous research, nature environments facilitated wellbeing-related attention restoration. However, this method did not provide an accurate multisensory experience, therefore lacking ecological validity. Chapter 5 investigated methodologies for controlling the exercise component, comparing wellbeing-related outcomes of indoor versus outdoor exercise. This was important because previous research had not rigorously controlled exercise, therefore potentially confounding its findings. Results for environment-related exercise differences and affective outcomes were inconclusive. Chapter 6 merged laboratory-based methods with the indoor versus outdoor exercise paradigm, ensuring control and ecological validity. Environmental setting did not influence perceived exertion or mood; green settings promoted attention restoration and social interaction; for green exercise, social interaction predicted exercise intentions. Green exercise promotes wellbeing improvements; environmental influences on affective outcomes may be contributed to by differences in exercise performed. Independent of exercise differences, green environments promote attention restoration and social interaction during exercise, which may in turn influence exercise intentions