934,976 research outputs found

    ICT Research, the New Economy, and the Evolving Discipline of Economics: Back to the Future?

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    Economics-related ICT research has moved from the fringes of the discipline to penetrate all of its branches. It is, therefore, not a separate economics sub-discipline. It is also unlikely to become part of an 'ICT or Internet Research' proto-discipline. Instead, it should be seen as only one part of a bigger agenda toward a proper 'information and knowledge economics' and possibly a future proto-discipline of a 'unified theory of information and knowledge' or a meta-discipline of information sciences. This is the post-print version of a short article for the Special Issue: ICT Research and Disciplinary Boundaries: Is “Internet Research” a Virtual Field, a Proto-Discipline, or Something Else?”(Guest Editor: Nancy K. Baym), Information Society, Volume 21, No. 4, 2005, pp. 317-320. See: http://www.indiana.edu/~tisj

    Management of cancer-associated anemia with erythropoiesis-stimulating agents: ASCO/ASH clinical practice guideline update.

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    PURPOSE: To update the American Society of Clinical Oncology (ASCO)/American Society of Hematology (ASH) recommendations for use of erythropoiesis-stimulating agents (ESAs) in patients with cancer. METHODS: PubMed and the Cochrane Library were searched for randomized controlled trials (RCTs) and meta-analyses of RCTs in patients with cancer published from January 31, 2010, through May 14, 2018. For biosimilar ESAs, the literature search was expanded to include meta-analyses and RCTs in patients with cancer or chronic kidney disease and cohort studies in patients with cancer due to limited RCT evidence in the cancer setting. ASCO and ASH convened an Expert Panel to review the evidence and revise previous recommendations as needed. RESULTS: The primary literature review included 15 meta-analyses of RCTs and two RCTs. A growing body of evidence suggests that adding iron to treatment with an ESA may improve hematopoietic response and reduce the likelihood of RBC transfusion. The biosimilar literature review suggested that biosimilars of epoetin alfa have similar efficacy and safety to reference products, although evidence in cancer remains limited. RECOMMENDATIONS: ESAs (including biosimilars) may be offered to patients with chemotherapy-associated anemia whose cancer treatment is not curative in intent and whose hemoglobin has declined to \u3c 10 g/dL. RBC transfusion is also an option. With the exception of selected patients with myelodysplastic syndromes, ESAs should not be offered to most patients with nonchemotherapy-associated anemia. During ESA treatment, hemoglobin may be increased to the lowest concentration needed to avoid transfusions. Iron replacement may be used to improve hemoglobin response and reduce RBC transfusions for patients receiving ESA with or without iron deficiency. Additional information is available at www.asco.org/supportive-care-guidelines and www.hematology.org/guidelines

    The Media in the Network Society: Browsing, News, Filters and Citizenship

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    560 p. : ill. ; 23 cm.Libro ElectrónicoIn the Network Society the development of a new communicational model has been taking shape. A communicational model characterized by the fusion of interpersonal communication and mass communication, connecting audiences and broadcasters under a hypertextual matrix linking several media devices. The Networked Communication model is the informational societies communication model. A model that must be understood also in its needed literacies for building our media diets, media matrixes and on how it’s changing the way autonomy is managed and citizenship exercised in the Information Age. In this book Gustavo Cardoso develops an analysis that, focusing on the last decade, takes us from Europe to North America and from South America to Asia, combining under the framework of the Network Society a broad range of scientific perspectives from Media Studies to Political Science and Social Movements theory to Sociology of Communication.Index of Figures Index of Tables Preface Acknowledgements The Media in the Network Society. Contextualizing the Media in the Network Society; Media, Autonomy and Citizenship 1. The Multiple Dimensions of the Network Society. The Network Society; The Culture of the Informational Societies 2. Societies in Transition to the Network Society. Societies in Transition in the Global Network; Societies in Transitions, Values and Social Well-Being; Media and Social Change in the Network Societies 3. From Mass to Networked Communication: Communicational Models and the Informational Society Communicational Models and the Informational Society. Communicational Globalization in the 20th Century; Mass Media and New Media: the Articulation of a New Communicational Model?; Rhetoric, Accessibility of Information and Narratives Networked Communication 4. A Constellation of Networks: Mass Media, Games, Internet and Telephones. An Entertainment Meta-System in Transition: from Multimedia Games to Television; The New Entertainment Player: Multimedia Games; The Reaffirmation of TV as a Central Element of the Entertainment Meta-System; From Interactive Television to Networked Television 5. Has the Internet Really Changed the Mass Media?. From the End of Journalism to Its Reconstruction; The Information Meta-System and Its Network Organization; Television: the New Online Functions; From Radio Interactivity to Newspaper; Time Management: the Media Network 6. The Massification of the Internet Experience. The New Frontiers and Their Entry Portals; Media, Memory and Filters 7. Media and Citizenship in the Network Society. Mediation of Citizenship and Informational Literacy; The Different Media Ages; Different Media Ages, Different Forms of Citizenship? 8. Mediated Politics: Citizens and Political Parties in Continuous Democracy; An Institutional and Parliamentary; Framework for Continuous Democracy; The Internet as Hostage of Institutional Informational Politics? 9. Media, Mobilization and Protests. Goku vs. The Ministry of Culture: Terràvista, Television and Newspapers; The Closure of RTP2: Television Seen from the Internet; The Pro-East Timor Movement: Human Rights, Mass Media and the Internet; Instrumentalization of the Networked Symbolic Mediation Conclusion: Browsing, News, Filters and Citizenship.Browsing, News, Filters and Citizenship Bibliograph

    The impacts of Meta Data Management on Social Dynamics: A Research Case Study

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    Meta data management practices often overlook the role social dynamics play in harnessing the value of an organisation’s unique business language and the behaviours it creates. Using evidence from literature, interviews and cognitive ethnography, this research case sets out to explain the impacts of meta data management on social dynamics. The emerging themes (that is, newness, continual adaption, engagement tension, production tension, inefficiency and unreliability) represent salient factors by which organisations can be constrained in exploiting the worth of their meta data. This research emphasises the critical importance of organisations having a deeper understanding of the purpose and meaning of information. This understanding is a strength for creating value and for exploiting the worth arising in networks and in the social dynamics created within those networks. This strength contributes to organisations’ economic growth and is interdependent with their ability to manage complex phenomenon in a growing interconnected society

    Fake News: Finding Truth in Strategic Communication

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    Fake news is an old phenomenon that has become a new obsession and a menace to society due to technological advancement and the proliferation of social media, which has changed traditional journalism norms. As the spread of false information has increased these past few years, it has become increasingly difficult for information consumers to distinguish between facts and fakes. A comprehensive systematic literature review to extract themes revealed the major factors responsible for spreading fake news. This qualitative interpretative meta-synthesis (QIMS) aims to better understand and offer solutions to combat fake news. This Ph.D. dissertation will serve as a guide for ethical communication practice and a reference for future research studies

    Comparative safety and efficacy of vasopressors for mortality in septic shock: A network meta-analysis

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    © 2015, © The Intensive Care Society 2015.Introduction: Septic shock is a life-threatening condition requiring vasopressor agents to support the circulatory system. Several agents exist with choice typically guided by the specific clinical scenario. We used a network meta-analysis approach to rate the comparative efficacy and safety of vasopressors for mortality and arrhythmia incidence in septic shock patients. Methods: We performed a comprehensive electronic database search including Medline, Embase, Science Citation Index Expanded and the Cochrane database. Randomised trials investigating vasopressor agents in septic shock patients and specifically assessing 28-day mortality or arrhythmia incidence were included. A Bayesian network meta-analysis was performed using Markov chain Monte Carlo methods. Results: Thirteen trials of low to moderate risk of bias in which 3146 patients were randomised were included. There was no pairwise evidence to suggest one agent was superior over another for mortality. In the network meta-analysis, vasopressin was significantly superior to dopamine (OR 0.68 (95% CI 0.5 to 0.94)) for mortality. For arrhythmia incidence, standard pairwise meta-analyses confirmed that dopamine led to a higher incidence of arrhythmias than norepinephrine (OR 2.69 (95% CI 2.08 to 3.47)). In the network meta-analysis, there was no evidence of superiority of one agent over another. Conclusions: In this network meta-analysis, vasopressin was superior to dopamine for 28-day mortality in septic shock. Existing pairwise information supports the use of norepinephrine over dopamine. Our findings suggest that dopamine should be avoided in patients with septic shock and that other vasopressor agents should continue to be based on existing guidelines and clinical judgement of the specific presentation of the patient

    Hybriding Technology In Organizational Communications In Government

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    The development of industry 4.0 has blurred the distance between the government and society through hybridization of technology that is applied by the government to support government transformation at the organizational and bureaucratic levels which can improve changes in organizational relations for the better. This can be seen from the new application that is used to become a bridge between the government and its citizens. In addition, the use of technology in the implementation of government performance that is more effective and efficient causes government organizations to be far from being as rigid as what has been attached to organizations so far. This research is a meta-synthesis research with a qualitative meta-aggregation approach. The results of the study show that based on the application of technology in government organizations, hybridization of technology within government organizations requires integration between information technology and social sciences, because technological hybridization is basically an organization that must be regulated
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