The Unexpected Impact of Information-Sharing on US Pharmaceutical Supply-Chains

This paper examines the introduction of information-sharing into the supply chains for pharmaceutical products in the United States. This introduction was unusual for several reasons. First, it was catalyzed from outside the industry, by a Securities and Exchange Commission (SEC) investigation into improper financial reporting by a single manufacturer. Second, it was initiated by pharmaceutical manufacturers in order to keep distributor inventories low. Third, although its effect on pharmaceutical distributors has been profound, evidence indicates that information-sharing has had no impact on pharmaceutical manufacturers' own inventorymanagement practices.

Disruptive Effects of the Coronavirus – Errors of Commission and of Omission?

It is increasingly evident that the coronavirus disease, COVID-19, is more than a health problem; it is and will continue to adversely affect work and workplaces, education, families and social engagements, political and environmental dimensions, and financial indicators. Apart from its health ramifications, the crisis is revealing serious challenges in the global supply chain. Those difficulties are, at least in part, consequences of unwise, short-sighted business decisions made over the course of decades to outsource and downsize

Inventory drivers in a pharmaceutical supply chain

In recent years, inventory reduction has been a key objective of pharmaceutical companies, especially within cost optimization initiatives. Pharmaceutical supply chains are characterized by volatile and unpredictable demands –especially in emergent markets-, high service levels, and complex, perishable finished-good portfolios, which makes keeping reasonable amounts of stock a true challenge. However, a one-way strategy towards zero-inventory is in reality inapplicable, due to the strategic nature and importance of the products being commercialised. Therefore, pharmaceutical supply chains are in need of new inventory strategies in order to remain competitive. Finished-goods inventory management in the pharmaceutical industry is closely related to the manufacturing systems and supply chain configurations that companies adopt. The factors considered in inventory management policies, however, do not always cover the full supply chain spectrum in which companies operate. This paper works under the pre-assumption that, in fact, there is a complex relationship between the inventory configurations that companies adopt and the factors behind them. The intention of this paper is to understand the factors driving high finished-goods inventory levels in pharmaceutical supply chains and assist supply chain managers in determining which of them can be influenced in order to reduce inventories to an optimal degree. Reasons for reducing inventory levels are found in high inventory holding and scrap related costs; in addition to lost sales for not being able to serve the customers with the adequate shelf life requirements. The thesis conducts a single case study research in a multi-national pharmaceutical company, which is used to examine typical inventory configurations and the factors affecting these configurations. This paper presents a framework that can assist supply chain managers in determining the most important inventory drivers in pharmaceutical supply chains. The findings in this study suggest that while external and downstream supply chain factors are recognized as being critical to pursue inventory optimization initiatives, pharmaceutical companies are oriented towards optimizing production processes and meeting regulatory requirements while still complying with high service levels, being internal factors the ones prevailing when making inventory management decisions. Furthermore, this paper investigates, through predictive modelling techniques, how various intrinsic and extrinsic factors influence the inventory configurations of the case study company. The study shows that inventory configurations are relatively unstable over time, especially in configurations that present high safety stock levels; and that production features and product characteristics are important explanatory factors behind high inventory levels. Regulatory requirements also play an important role in explaining the high strategic inventory levels that pharmaceutical companies hold

After Heparin: Protecting Consumers From the Risks of Substandard and Counterfeit Drugs

Based on case studies, examines globalization and quality management trends in pharmaceutical manufacturing, barriers to Federal Drug Administration oversight, and the security of pharmaceutical distribution. Makes policy recommendations to ensure safety

Future Agribusiness Challenges: Strategic Uncertainty, Innovation and Structural Change

The IFAMR is published by the International Food and Agribusiness Management Association.(IFAMA) www.ifama.orgStrategic uncertainty, innovation, structural change, Agribusiness, Research and Development/Tech Change/Emerging Technologies, Risk and Uncertainty, ISSN #: 1559-2448,

Supply chain information visibility and its impact on decision-making : an integrated model in the pharmaceutical industry : a dissertation presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Management at Massey University, Albany, Auckland, New Zealand

Supply chain information visibility (SCIV) has been largely recognized as a key issue in pharmaceutical supply chain management. In recent years, there has been growing concern regarding the exponential growth and ubiquity of supply chain information as the result of the application of advanced technologies. Thus, the topic of visibility of information flow across a supply chain has attracted interest in both practice and academia. Despite the existence of considerable literature on SCIV, the concept is still under-theorized. The lack of a clear understanding of the characteristics of SCIV has made it difficult to evaluate the effectiveness of SCIV and, consequently, hinders the improvement of SCIV (McIntire, 2014). Second, recent research identifies the potential of SCIV for operational performance through supporting managerial decision-making but also points out challenges and risks. In addition, there is a dearth of behavioral empirical research on supply chain management topics with which to achieve an increase in theory-building research in the field. This research addresses these gaps in the literature and investigates how SCIV across the pharmaceutical supply chain is perceived by pharmaceutical supply chain practitioners who are involved in supply chain decision-making, and how the decision-makers make use of SCIV in their supply chain decision-making process. This study adopted an exploratory, and qualitative approach to address two research questions: “How do supply chain professionals perceive SCIV in the pharmaceutical supply chain?” and “How do supply chain professionals make informed supply chain decisions?” The constructivist grounded theory methodology was used to guide the data gathering and analysis. The data were mainly drawn from semi-structured interviews with supply chain practitioners in New Zealand-based pharmaceutical firms, working at different levels of the supply chain, including manufacturers and distributors. Based on the findings a theoretical model was developed, the Pharmaceutical Supply Chain Information-based Decision-Making Model. The model explains the behavioral supply chain decision-making process in the pharmaceutical supply chain, based on the existence of a given level of SCIV. The empirical findings suggest that SCIV is achieved both within and outside of the pharmaceutical firms and that human relational factors tend to be more beneficial than technological factors in developing SCIV. The importance of this finding is that it addresses a frequently asked question in recent literature about what constitutes SCIV and how to successfully build information visibility in a supply chain. Moreover, this research contributes to the behavioural supply chain management research literature by introducing a theoretical model of pharmaceutical supply chain information-based decision-making, which is grounded in the field data. The model offers significant theoretical insight into information-based decision-making in the pharmaceutical supply chain context based on empirical data, which has been largely overlooked in the supply chain management discipline. The empirical findings suggest that supply chain practitioners make information-based decisions in which they conduct an informative engaging mechanism with technological tools, with relevant stakeholders, and with themselves. Thus, the decision-making process involves extensive data analysis along with the crucial support of experience-based intuition and relevant stakeholders’ engagement. Another key contribution of this study is the identification of the constructive aspect of political behaviour in the supply chain decision-making process in which relevant stakeholders when invited to engage in the process tend to positively contribute and buy into the decision. Finally, this thesis provides significant practical implications and suggest directions for future research. Supply chain practitioners may benefit from the study by utilizing the study’s results to develop supply chain information visibility in their firms. In addition, the theoretical model of the information-based decision-making process explicates a useful step-by-step approach for supply chain practitioners to follow in making effective supply chain operational decisions. Recommendations for further research are provided, especially the recommendations for further studies that are crucially needed to assist firms to counter the pharmaceutical supply chain disruption risks caused by the Covid-19 pandemic

A refined framework of information sharing in perishable product supply chains

Purpose The purpose of this paper is to contribute to the understanding of the relationship between information sharing and performance of perishable product supply chains (PPSC). Building on transaction cost economics (TCE), organisational information processing theory (OIPT), and contingency theory (CT), this study proposes a theoretical framework to guide future research into information sharing in perishable product supply chains (IS-PPSC). Design/methodology/approach Using the systematic literature review methodology, 48 peer-reviewed articles are carefully selected, mapped, and assessed. Template analysis is performed to unravel the relationship mechanisms between information sharing and PPSC performance. Findings The authors find that the relationship between information sharing and PPSC performance is currently unclear, and there is inconsistency in the positioning of information sharing among constructs and variables in the IS-PPSC literature. This implies a requirement to refine the relationship between information sharing and PPSC performance. The review also revealed that the role of perishable product characteristics has largely been ignored in existing research. Originality/value This study applies relevant multiple theoretical perspectives to overcome the ambiguity of the IS-PPSC literature and contributes nine propositions to guide future research. Accordingly, this study contributes to the refined roles of relationship uncertainty, environmental uncertainty, information sharing capabilities, and perishable product characteristics in shaping the relationship between information sharing and PPSC performance

Securing the Post-Covid Pharma Supply Chain: An Empirical Investigation

The pandemic outbreak of Covid-19 has shown the fragilities and vulnerabilities of the Pharma Supply Chain (PSC), leading academics and practitioners to rethink PSCs’ flexibility, agility, responsiveness, and resilience. This paper investigates how to secure the Post-Covid PSC by (i) classifying the challenges born of or aggravated by the pandemic; (ii) understanding how solutions enabled by Industry 4.0 technologies can be integrated into a framework to address and solve the above challenges. A theoretical framework was developed from a literature review to achieve these objectives, which was then confirmed and enriched by a multiple case study investigation

Resilience-enhancing solution to mitigate risk for sustainable supply chain-an empirical study of elevator manufacturing

As the complexity of supply chains increases, the enhancement of resilience for mitigating sustainable disruption risks in supply chains is an important issue. Quality function deployment (QFD) has been successfully applied in many domains to solve multicriteria decision-making (MCDM) problems. However, research on developing two houses of quality to connect sustainable supply chain disruption risks, resilience capacities, and resilience-enhancing features in elevator manufacturing supply chains by using the MCDM approach is lacking. This study aims to develop a framework for exploring useful decision-making by integrating the MCDM approach and QFD. By applying the framework, supply chain resilience can be improved by identifying the major sustainable risks and the key resilience to mitigate these risks. Important managerial insights and practical implications are obtained from the framework implementation in a case study of the elevator manufacturing industry. To strengthen resilience and thus mitigate key risks, the most urgent tasks are to connect the working site and the backstage to enhance product development and design and to share real-time job information. When these features are strengthened, agility, capacity, and visibility can be improved. Finally, unexpected events lead to changes in supplier delivery dates, and factors such as typhoon and lack of critical capacities/skilled employees with the greatest impact can be alleviated. This framework will provide an effective and pragmatic approach for constructing sustainable supply chain risk resilience in the elevator manufacturing industry.</p

Knowledge acquisition in supply chain partnerships: The role of power

This is the post-print version of the final paper published in International Journal of Production Economics. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 Elsevier B.V.Knowledge is recognised as an important source of competitive advantage and hence there has been increasing academic and practitioner interest in understanding and isolating the factors that contribute to effective knowledge transfer between supply chain actors. The literature identifies power as a salient contributor to the effective operation of a supply chain partnership. However, there is a paucity of empirical research examining how power among actors influences knowledge acquisition and in turn the performance of supply chain partners. The aim of this research is to address this gap by examining the relationship between power, knowledge acquisition and supply chain performance among the supply chain partners of a focal Chinese steel manufacturer. A structured survey was used to collect the necessary data. Two conceptually independent variables – ‘availability of alternatives’ and ‘restraint in the use of power’ – were used to assess actual and realised power, respectively. Controlling for contingencies, we found that the flow of knowledge increased when supply chain actors had limited alternatives and when the more powerful actor exercised restraint in the use of power. Moreover, we found a positive relationship between knowledge acquisition and supply chain performance. This paper enriches the literature by empirically extending our understanding of how power affects knowledge acquisition and performance