Enhancing pharmaceutical packaging through a technology ecosystem to facilitate the reuse of medicines and reduce medicinal waste

The idea of reusing dispensed medicines is appealing to the general public provided its benefits are illustrated, its risks minimized, and the logistics resolved. For example, medicine reuse could help reduce medicinal waste, protect the environment and improve public health. However, the associated technologies and legislation facilitating medicine reuse are generally not available. The availability of suitable technologies could arguably help shape stakeholders’ beliefs and in turn, uptake of a future medicine reuse scheme by tackling the risks and facilitating the practicalities. A literature survey is undertaken to lay down the groundwork for implementing technologies on and around pharmaceutical packaging in order to meet stakeholders’ previously expressed misgivings about medicine reuse (’stakeholder requirements’), and propose a novel ecosystem for, in effect, reusing returned medicines. Methods: A structured literature search examining the application of existing technologies on pharmaceutical packaging to enable medicine reuse was conducted and presented as a narrative review. Results: Reviewed technologies are classified according to different stakeholders’ requirements, and a novel ecosystem from a technology perspective is suggested as a solution to reusing medicines. Conclusion: Active sensing technologies applying to pharmaceutical packaging using printed electronics enlist medicines to be part of the Internet of Things network. Validating the quality and safety of returned medicines through this network seems to be the most effective way for reusing medicines and the correct application of technologies may be the key enabler

Data Hiding In Contourlet Coefficients Based On Their Energy

The data hiding is one of the most important subject in field of computer science, so a lot of technique was developed and modified to satisfy the optimum lend of hiding. In this research the contourlet transformation coefficients were studied to decide which of them are suitable to embed data on it a lot of parameters of the contourlet coefficients can be discussed one of them is the coefficient energy.The research covered most of the suggested events which could be met during the embedding state, one of them the size of the cover in addition to the size of the information were studied. Applying the suggested idea on different type of image with different size (cover image and the message image) shows that the coefficients with low level of energy are suitable to embedded the information, and the retrieved cover and message are so closed to the original one

Towards the Avoidance of Counterfeit Memory: Identifying the DRAM Origin

Due to the globalization in the semiconductor supply chain, counterfeit dynamic random-access memory (DRAM) chips/modules have been spreading worldwide at an alarming rate. Deploying counterfeit DRAM modules into an electronic system can have severe consequences on security and reliability domains because of their sub-standard quality, poor performance, and shorter life span. Besides, studies suggest that a counterfeit DRAM can be more vulnerable to sophisticated attacks. However, detecting counterfeit DRAMs is very challenging because of their nature and ability to pass the initial testing. In this paper, we propose a technique to identify the DRAM origin (i.e., the origin of the manufacturer and the specification of individual DRAM) to detect and prevent counterfeit DRAM modules. A silicon evaluation shows that the proposed method reliably identifies off-the-shelf DRAM modules from three major manufacturers

Non-invasive Techniques Towards Recovering Highly Secure Unclonable Cryptographic Keys and Detecting Counterfeit Memory Chips

Due to the ubiquitous presence of memory components in all electronic computing systems, memory-based signatures are considered low-cost alternatives to generate unique device identifiers (IDs) and cryptographic keys. On the one hand, this unique device ID can potentially be used to identify major types of device counterfeitings such as remarked, overproduced, and cloned. On the other hand, memory-based cryptographic keys are commercially used in many cryptographic applications such as securing software IP, encrypting key vault, anchoring device root of trust, and device authentication for could services. As memory components generate this signature in runtime rather than storing them in memory, an attacker cannot clone/copy the signature and reuse them in malicious activity. However, to ensure the desired level of security, signatures generated from two different memory chips should be completely random and uncorrelated from each other. Traditionally, memory-based signatures are considered unique and uncorrelated due to the random variation in the manufacturing process. Unfortunately, in previous studies, many deterministic components of the manufacturing process, such as memory architecture, layout, systematic process variation, device package, are ignored. This dissertation shows that these deterministic factors can significantly correlate two memory signatures if those two memory chips share the same manufacturing resources (i.e., manufacturing facility, specification set, design file, etc.). We demonstrate that this signature correlation can be used to detect major counterfeit types in a non-invasive and low-cost manner. Furthermore, we use this signature correlation as side-channel information to attack memory-based cryptographic keys. We validate our contribution by collecting data from several commercially available off-the-shelf (COTS) memory chips/modules and considering different usage-case scenarios

Robust image steganography method suited for prining = Robustna steganografska metoda prilagođena procesu tiska

U ovoj doktorskoj dizertaciji prezentirana je robustna steganografska metoda razvijena i prilagođena za tisak. Osnovni cilj metode je pružanje zaštite od krivotvorenja ambalaže. Zaštita ambalaže postiže se umetanjem više bitova informacije u sliku pri enkoderu, a potom maskiranjem informacije kako bi ona bila nevidljiva ljudskom oku. Informacija se pri dekoderu detektira pomoću infracrvene kamere. Preliminarna istraživanja pokazala su da u relevantnoj literaturi nedostaje metoda razvijenih za domenu tiska. Razlog za takav nedostatak jest činjenica da razvijanje steganografskih metoda za tisak zahtjeva veću količinu resursa i materijala, u odnosu na razvijanje sličnih domena za digitalnu domenu. Također, metode za tisak često zahtijevaju višu razinu kompleksnosti, budući da se tijekom reprodukcije pojavljuju razni oblici procesiranja koji mogu kompromitirati informaciju u slici [1]. Da bi se sačuvala skrivena informacija, metoda mora biti otporna na procesiranje koje se događa tijekom reprodukcije. Kako bi se postigla visoka razina otpornosti, informacija se može umetnuti unutar frekvencijske domene slike [2], [3]. Frekvencijskoj domeni slike možemo pristupiti pomoću matematičkih transformacija. Najčešće se koriste diskretna kosinusna transformacija (DCT), diskretna wavelet transformacija (DWT) i diskretna Fourierova transformacija (DFT) [2], [4]. Korištenje svake od navedenih transformacija ima određene prednosti i nedostatke, ovisno o kontekstu razvijanja metode [5]. Za metode prilagođene procesu tiska, diskretna Fourierova transformacija je optimalan odabir, budući da metode bazirane na DFT-u pružaju otpornost na geometrijske transformacije koje se događaju tijekom reprodukcije [5], [6]. U ovom istraživanju korištene su slike u cmyk prostoru boja. Svaka slika najprije je podijeljena u blokove, a umetanje informacije vrši se za svaki blok pojedinačno. Pomoću DFT-a, ???? kanal slikovnog bloka se transformira u frekvencijsku domenu, gdje se vrši umetanje informacije. Akromatska zamjena koristi se za maskiranje vidljivih artefakata nastalih prilikom umetanja informacije. Primjeri uspješnog korištenja akromatske zamjene za maskiranje artefakata mogu se pronaći u [7] i [8]. Nakon umetanja informacije u svaki slikovni blok, blokovi se ponovno spajaju u jednu, jedinstvenu sliku. Akromatska zamjena tada mijenja vrijednosti c, m i y kanala slike, dok kanal k, u kojemu se nalazi umetnuta informacija, ostaje nepromijenjen. Time nakon maskiranja akromatskom zamjenom označena slika posjeduje ista vizualna svojstva kao i slika prije označavanja. U eksperimentalnom dijelu rada koristi se 1000 slika u cmyk prostoru boja. U digitalnom okruženju provedeno je istraživanje otpornosti metode na slikovne napade specifične za reprodukcijski proces - skaliranje, blur, šum, rotaciju i kompresiju. Također, provedeno je istraživanje otpornosti metode na reprodukcijski proces, koristeći tiskane uzorke. Objektivna metrika bit error rate (BER) korištena je za evaluaciju. Mogućnost optimizacije metode testirala se procesiranjem slike (unsharp filter) i korištenjem error correction kodova (ECC). Provedeno je istraživanje kvalitete slike nakon umetanja informacije. Za evaluaciju su korištene objektivne metrike peak signal to noise ratio (PSNR) i structural similarity index measure (SSIM). PSNR i SSIM su tzv. full-reference metrike. Drugim riječima, potrebne su i neoznačena i označena slika istovremeno, kako bi se mogla utvrditi razina sličnosti između slika [9], [10]. Subjektivna analiza provedena je na 36 ispitanika, koristeći ukupno 144 uzorka slika. Ispitanici su ocijenjivali vidljivost artefakata na skali od nula (nevidljivo) do tri (vrlo vidljivo). Rezultati pokazuju da metoda posjeduje visoku razinu otpornosti na reprodukcijski proces. Također, metoda se uistinu optimizirala korištenjem unsharp filtera i ECC-a. Kvaliteta slike ostaje visoka bez obzira na umetanje informacije, što su potvrdili rezultati eksperimenata s objektivnim metrikama i subjektivna analiza

Digital watermarking and novel security devices

EThOS - Electronic Theses Online ServiceGBUnited Kingdo