On Measures and Measurements: a Fibre Bundle approach to Contextuality

Contextuality is the failure of "local" probabilistic models to become global ones. In this paper we introduce the notions of \emph{measurable fibre bundles}, \emph{probability fibre bundles}, and \emph{sample fibre bundle} which capture and make precise the former statement. The central notions of contextuality are discussed under this formalism, examples worked out, and some new aspects pointed out.Comment: 14 pages; no figures; Purdue-Winer Memorial Lectures 2018; submitted to Phil. Trans. Roy. Soc. A. Comments are very welcom

Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids

The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp. and Trypanosoma brucei and found evidences for its expression as a specific RNA class. The trypanosomatid TERRA are heterogeneous in size and partially polyadenylated. The levels of TERRA transcripts appear to be modulated through the life cycle in both trypanosomatids investigated, suggesting that TERRA play a stage-specific role in the life cycle of these early-branching eukaryotes