41,105 research outputs found
Stratified decision forests for accurate anatomical landmark localization in cardiac images
Accurate localization of anatomical landmarks is an important step in medical imaging, as it provides useful prior information for subsequent image analysis and acquisition methods. It is particularly useful for initialization of automatic image analysis tools (e.g. segmentation and registration) and detection of scan planes for automated image acquisition. Landmark localization has been commonly performed using learning based approaches, such as classifier and/or regressor models. However, trained models may not generalize well in heterogeneous datasets when the images contain large differences due to size, pose and shape variations of organs. To learn more data-adaptive and patient specific models, we propose a novel stratification based training model, and demonstrate its use in a decision forest. The proposed approach does not require any additional training information compared to the standard model training procedure and can be easily integrated into any decision tree framework. The proposed method is evaluated on 1080 3D highresolution and 90 multi-stack 2D cardiac cine MR images. The experiments show that the proposed method achieves state-of-theart landmark localization accuracy and outperforms standard regression and classification based approaches. Additionally, the proposed method is used in a multi-atlas segmentation to create a fully automatic segmentation pipeline, and the results show that it achieves state-of-the-art segmentation accuracy
Multi-Entity Dependence Learning with Rich Context via Conditional Variational Auto-encoder
Multi-Entity Dependence Learning (MEDL) explores conditional correlations
among multiple entities. The availability of rich contextual information
requires a nimble learning scheme that tightly integrates with deep neural
networks and has the ability to capture correlation structures among
exponentially many outcomes. We propose MEDL_CVAE, which encodes a conditional
multivariate distribution as a generating process. As a result, the variational
lower bound of the joint likelihood can be optimized via a conditional
variational auto-encoder and trained end-to-end on GPUs. Our MEDL_CVAE was
motivated by two real-world applications in computational sustainability: one
studies the spatial correlation among multiple bird species using the eBird
data and the other models multi-dimensional landscape composition and human
footprint in the Amazon rainforest with satellite images. We show that
MEDL_CVAE captures rich dependency structures, scales better than previous
methods, and further improves on the joint likelihood taking advantage of very
large datasets that are beyond the capacity of previous methods.Comment: The first two authors contribute equall
Machine learning to analyze single-case data : a proof of concept
Visual analysis is the most commonly used method for interpreting data from singlecase designs, but levels of interrater agreement remain a concern. Although structured
aids to visual analysis such as the dual-criteria (DC) method may increase interrater
agreement, the accuracy of the analyses may still benefit from improvements. Thus, the
purpose of our study was to (a) examine correspondence between visual analysis and
models derived from different machine learning algorithms, and (b) compare the
accuracy, Type I error rate and power of each of our models with those produced by
the DC method. We trained our models on a previously published dataset and then
conducted analyses on both nonsimulated and simulated graphs. All our models
derived from machine learning algorithms matched the interpretation of the visual
analysts more frequently than the DC method. Furthermore, the machine learning
algorithms outperformed the DC method on accuracy, Type I error rate, and power.
Our results support the somewhat unorthodox proposition that behavior analysts may
use machine learning algorithms to supplement their visual analysis of single-case data,
but more research is needed to examine the potential benefits and drawbacks of such an
approach
Mondrian Forests for Large-Scale Regression when Uncertainty Matters
Many real-world regression problems demand a measure of the uncertainty
associated with each prediction. Standard decision forests deliver efficient
state-of-the-art predictive performance, but high-quality uncertainty estimates
are lacking. Gaussian processes (GPs) deliver uncertainty estimates, but
scaling GPs to large-scale data sets comes at the cost of approximating the
uncertainty estimates. We extend Mondrian forests, first proposed by
Lakshminarayanan et al. (2014) for classification problems, to the large-scale
non-parametric regression setting. Using a novel hierarchical Gaussian prior
that dovetails with the Mondrian forest framework, we obtain principled
uncertainty estimates, while still retaining the computational advantages of
decision forests. Through a combination of illustrative examples, real-world
large-scale datasets, and Bayesian optimization benchmarks, we demonstrate that
Mondrian forests outperform approximate GPs on large-scale regression tasks and
deliver better-calibrated uncertainty assessments than decision-forest-based
methods.Comment: Proceedings of the 19th International Conference on Artificial
Intelligence and Statistics (AISTATS) 2016, Cadiz, Spain. JMLR: W&CP volume
5
- …