Deep Learning in Cardiology

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning has emerged as a more accurate and effective technology in a wide range of medical problems such as diagnosis, prediction and intervention. Deep learning is a representation learning method that consists of layers that transform the data non-linearly, thus, revealing hierarchical relationships and structures. In this review we survey deep learning application papers that use structured data, signal and imaging modalities from cardiology. We discuss the advantages and limitations of applying deep learning in cardiology that also apply in medicine in general, while proposing certain directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table

Adapted Compressed Sensing: A Game Worth Playing

Despite the universal nature of the compressed sensing mechanism, additional information on the class of sparse signals to acquire allows adjustments that yield substantial improvements. In facts, proper exploitation of these priors allows to significantly increase compression for a given reconstruction quality. Since one of the most promising scopes of application of compressed sensing is that of IoT devices subject to extremely low resource constraint, adaptation is especially interesting when it can cope with hardware-related constraint allowing low complexity implementations. We here review and compare many algorithmic adaptation policies that focus either on the encoding part or on the recovery part of compressed sensing. We also review other more hardware-oriented adaptation techniques that are actually able to make the difference when coming to real-world implementations. In all cases, adaptation proves to be a tool that should be mastered in practical applications to unleash the full potential of compressed sensing

Deep fusion of multi-channel neurophysiological signal for emotion recognition and monitoring

How to fuse multi-channel neurophysiological signals for emotion recognition is emerging as a hot research topic in community of Computational Psychophysiology. Nevertheless, prior feature engineering based approaches require extracting various domain knowledge related features at a high time cost. Moreover, traditional fusion method cannot fully utilise correlation information between different channels and frequency components. In this paper, we design a hybrid deep learning model, in which the 'Convolutional Neural Network (CNN)' is utilised for extracting task-related features, as well as mining inter-channel and inter-frequency correlation, besides, the 'Recurrent Neural Network (RNN)' is concatenated for integrating contextual information from the frame cube sequence. Experiments are carried out in a trial-level emotion recognition task, on the DEAP benchmarking dataset. Experimental results demonstrate that the proposed framework outperforms the classical methods, with regard to both of the emotional dimensions of Valence and Arousal

The Impact of Digital Technologies on Public Health in Developed and Developing Countries

This open access book constitutes the refereed proceedings of the 18th International Conference on String Processing and Information Retrieval, ICOST 2020, held in Hammamet, Tunisia, in June 2020.* The 17 full papers and 23 short papers presented in this volume were carefully reviewed and selected from 49 submissions. They cover topics such as: IoT and AI solutions for e-health; biomedical and health informatics; behavior and activity monitoring; behavior and activity monitoring; and wellbeing technology. *This conference was held virtually due to the COVID-19 pandemic

Improving Access and Mental Health for Youth Through Virtual Models of Care

The overall objective of this research is to evaluate the use of a mobile health smartphone application (app) to improve the mental health of youth between the ages of 14–25 years, with symptoms of anxiety/depression. This project includes 115 youth who are accessing outpatient mental health services at one of three hospitals and two community agencies. The youth and care providers are using eHealth technology to enhance care. The technology uses mobile questionnaires to help promote self-assessment and track changes to support the plan of care. The technology also allows secure virtual treatment visits that youth can participate in through mobile devices. This longitudinal study uses participatory action research with mixed methods. The majority of participants identified themselves as Caucasian (66.9%). Expectedly, the demographics revealed that Anxiety Disorders and Mood Disorders were highly prevalent within the sample (71.9% and 67.5% respectively). Findings from the qualitative summary established that both staff and youth found the software and platform beneficial

Machine Learning Models for High-dimensional Biomedical Data

abstract: The recent technological advances enable the collection of various complex, heterogeneous and high-dimensional data in biomedical domains. The increasing availability of the high-dimensional biomedical data creates the needs of new machine learning models for effective data analysis and knowledge discovery. This dissertation introduces several unsupervised and supervised methods to help understand the data, discover the patterns and improve the decision making. All the proposed methods can generalize to other industrial fields. The first topic of this dissertation focuses on the data clustering. Data clustering is often the first step for analyzing a dataset without the label information. Clustering high-dimensional data with mixed categorical and numeric attributes remains a challenging, yet important task. A clustering algorithm based on tree ensembles, CRAFTER, is proposed to tackle this task in a scalable manner. The second part of this dissertation aims to develop data representation methods for genome sequencing data, a special type of high-dimensional data in the biomedical domain. The proposed data representation method, Bag-of-Segments, can summarize the key characteristics of the genome sequence into a small number of features with good interpretability. The third part of this dissertation introduces an end-to-end deep neural network model, GCRNN, for time series classification with emphasis on both the accuracy and the interpretation. GCRNN contains a convolutional network component to extract high-level features, and a recurrent network component to enhance the modeling of the temporal characteristics. A feed-forward fully connected network with the sparse group lasso regularization is used to generate the final classification and provide good interpretability. The last topic centers around the dimensionality reduction methods for time series data. A good dimensionality reduction method is important for the storage, decision making and pattern visualization for time series data. The CRNN autoencoder is proposed to not only achieve low reconstruction error, but also generate discriminative features. A variational version of this autoencoder has great potential for applications such as anomaly detection and process control.Dissertation/ThesisDoctoral Dissertation Industrial Engineering 201

Algoritmos avanzados para detección del síndrome de apnea-hipopnea obstructiva del sueño

El Síndrome de Apnea-Hipopnea Obstructiva del Sueño (SAHOS) es un trastorno del sueño muy prevalente en la población general y con afectación de múltiples órganos. Se estima que esta patología afecta entre el 3% y 5% de la población adulta en todo el mundo y aumenta con la edad. Si bien el SAHOS es más frecuente en adultos, afecta también a niños con una prevalencia cercana al 3%. Los eventos respiratorios asociados al SAHOS durante el sueño ocurren como consecuencia de una alteración anatómico-funcional de la vía aérea superior que producen su estrechamiento parcial (hipopnea) o su bloqueo total (apnea). Para establecer el grado de severidad del SAHOS, se define el Índice de Apnea-Hipopnea. Éste índice representa el número de eventos de apnea-hipopnea por hora de sueño. El estudio de referencia para el correcto diagnóstico del SAHOS es la Polisomnografía nocturna. Dado que este tipo de estudio requiere no solo de la medición simultánea de una gran cantidad de señales fisiológicas, sino también de una infraestructura especial y de personal calificado, es de muy difícil acceso y muy costosa en términos de tiempo y dinero.En esta tesis se aborda el diseño, desarrollo, implementación y evaluación de tres métodos para el reconocimiento automático de los eventos de apnea-hipopnea a partir del análisis y procesamiento de las señales de saturación de oxígeno en sangre (SaO2). En particular, se presentan dos métodos de selección de características denominados MDAS y MDCS, los cuales se basan en representaciones ralas de señales de SaO2 para el reconocimiento de eventos de apnea-hipopnea. Además, en esta tesis se introduce una nueva medida de discriminabilidad binaria denotada por DCAF, la cual es capaz de detectar átomos discriminativos en un diccionario. Asimismo, esta medida permite cuantificar eficientemente sus correspondientes grados de discriminabilidad, lo cual resulta útil a los efectos de la clasificación. Los métodos MDAS y MDCS hacen uso de la media DCAF para detectar los átomos más discriminativos de un diccionario dado y, a partir de ellos, realizan la selección de características. En particular, el método MDCS utiliza la medida DCAF para seleccionar los átomos más discriminativos y, a partir de ellos, construir un sub-diccionario. En base a los experimentos desarrollados en esta tesis, el desempeño de la nueva medida DCAF fue comparada con el de varias otras medidas de información del estado del arte. Los resultados muestran que DCAF logró un muy buen desempeño. Por otro lado, el nuevo método MDCS fue comparado con otros tres métodos del estado de arte, superando significativamente el desempeño de todos ellos.Esta tesis introduce además una extensión del problema de clasificación binaria a uno multi-clase. En este contexto, se propone una generalización de la medida DCAF (la cual tiene en cuenta solo dos clases en los datos) a más de dos clases. En particular, la nueva medida de discriminabilidad combinada no solo tiene en cuenta la probabilidad condicional de activación de los átomos en un diccionario dada la clase y el valor de su correspondiente coeficiente de activación, sino que también incorpora el efecto que éste tiene sobre el error total de representación. Asimismo, se presenta un nuevo método iterativo llamado DAS-KSVD para el aprendizaje de diccionarios estructurados en el contexto de problemas de clasificación multi-clase, que utiliza ésta medida. El nuevo método permite detectar los átomos más discriminativos para cada una de las clases. Utilizando una base de datos de dígitos manuscritos ampliamente utilizada en la literatura, se realizó un análisis del desempeño del método DAS-KSVD obteniéndose tasas de reconocimiento superiores a las obtenidas por técnicas semejantes del estado del arte. También se utilizó el nuevo método DAS-KSVD en un problema de clasificación multi-clase asociado al SAHOS. Los resultados obtenidos muestran que éste método tiene un muy buen desempeño en la detección de la patología.Fil: Rolon, Roman Emanuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigación en Señales, Sistemas e Inteligencia Computacional. Universidad Nacional del Litoral. Facultad de Ingeniería y Ciencias Hídricas. Instituto de Investigación en Señales, Sistemas e Inteligencia Computacional; Argentin