Computer Aided ECG Analysis - State of the Art and Upcoming Challenges

In this paper we present current achievements in computer aided ECG analysis and their applicability in real world medical diagnosis process. Most of the current work is covering problems of removing noise, detecting heartbeats and rhythm-based analysis. There are some advancements in particular ECG segments detection and beat classifications but with limited evaluations and without clinical approvals. This paper presents state of the art advancements in those areas till present day. Besides this short computer science and signal processing literature review, paper covers future challenges regarding the ECG signal morphology analysis deriving from the medical literature review. Paper is concluded with identified gaps in current advancements and testing, upcoming challenges for future research and a bullseye test is suggested for morphology analysis evaluation.Comment: 7 pages, 3 figures, IEEE EUROCON 2013 International conference on computer as a tool, 1-4 July 2013, Zagreb, Croati

A FPGA system for QRS complex detection based on Integer Wavelet Transform

Due to complexity of their mathematical computation, many QRS detectors are implemented in software and cannot operate in real time. The paper presents a real-time hardware based solution for this task. To filter ECG signal and to extract QRS complex it employs the Integer Wavelet Transform. The system includes several components and is incorporated in a single FPGA chip what makes it suitable for direct embedding in medical instruments or wearable health care devices. It has sufficient accuracy (about 95%), showing remarkable noise immunity and low cost. Additionally, each system component is composed of several identical blocks/cells what makes the design highly generic. The capacity of today existing FPGAs allows even dozens of detectors to be placed in a single chip. After the theoretical introduction of wavelets and the review of their application in QRS detection, it will be shown how some basic wavelets can be optimized for easy hardware implementation. For this purpose the migration to the integer arithmetic and additional simplifications in calculations has to be done. Further, the system architecture will be presented with the demonstrations in both, software simulation and real testing. At the end, the working performances and preliminary results will be outlined and discussed. The same principle can be applied with other signals where the hardware implementation of wavelet transform can be of benefit

Electrocardiogram Baseline Wander Suppression Based on the Combination of Morphological and Wavelet Transformation Based Filtering

One of the major noise components in electrocardiogram (ECG) is the baseline wander (BW). Effective methods for suppressing BW include the wavelet-based (WT) and the mathematical morphological filtering-based (MMF)algorithms. However, the T waveform distortions introduced by the WTand the rectangular/trapezoidal distortions introduced by MMF degrade the quality of the output signal. Hence, in this study, we introduce a method by combining the MMF and WTto overcome the shortcomings of both existing methods. To demonstrate the effectiveness of the proposed method, artificial ECG signals containing a clinicalBW are used for numerical simulation, and we also create a realistic model of baseline wander to compare the proposed method with other state-of-the-art methods commonly used in the literature. /e results show that the BW suppression effect of the proposed method is better than that of the others. Also, the new method is capable of preserving the outline of the BW and avoiding waveform distortions caused by the morphology filter, thereby obtaining an enhanced quality of ECG

An evaluation of planarity of the spatial QRS loop by three dimensional vectorcardiography: its emergence and loss

Aims: To objectively characterize and mathematically justify the observation that vectorcardiographic QRS loops in normal individuals are more planar than those from patients with ST elevation myocardial infarction (STEMI). Methods: Vectorcardiograms (VCGs) were constructed from three simultaneously recorded quasi-orthogonal leads, I, aVF and V2 (sampled at 1000 samples/s). The planarity of these QRS loops was determined by fitting a surface to each loop. Goodness of fit was expressed in numerical terms. Results: 15 healthy individuals aged 35–65 years (73% male) and 15 patients aged 45–70 years (80% male) with diagnosed acute STEMI were recruited. The spatial-QRS loop was found to lie in a plane in normal controls. In STEMI patients, this planarity was lost. Calculation of goodness of fit supported these visual observations. Conclusions: The degree of planarity of the VCG loop can differentiate healthy individuals from patients with STEMI. This observation is compatible with our basic understanding of the electrophysiology of the human heart

Smart Device for the Determination of Heart Rate Variability in Real Time

This work presents a first approach to the design, development, and implementation of a smart device for the real-time measurement and detection of alterations in heart rate variability (HRV). The smart device follows a modular design scheme, which consists of an electrocardiogram (ECG) signal acquisition module, a processing module and a wireless communications module. From five-minute ECG signals, the processing module algorithms perform a spectral estimation of the HRV. The experimental results demonstrate the viability of the smart device and the proposed processing algorithms.Fundación Pública Andaluza Progreso y Salud. Gobierno de Andalucía PI-0010-2013 y PI-0041-2014Ministerio de Economía y Competitividad (Instituto de Salud Carlos III) PI15 / 00306 y DTS15 / 00195CIBER-BBN INT-2-CAR