193,282 research outputs found
Greening of the World of Work: O*NET® Project’s Book of References
[Excerpt] The National Center for O*NET Development, as part of its efforts to keep up with the changing world of work, investigated the impact of green economy activities and technologies on occupational requirements and the development of New and Emerging (N&E) occupations. Results of the research led to the identification of green economic sectors, green increased demand occupations, green enhanced skills occupations, and green new and emerging (N&E) occupations. These occupations are now reflected in the O*NET-SOC system. References used in this research are presented in this book
Bringing together emerging and endemic zoonoses surveillance: shared challenges and a common solution
Early detection of disease outbreaks in human and animal populations is crucial to the effective surveillance of emerging infectious diseases. However, there are marked geographical disparities in capacity for early detection of outbreaks, which limit the effectiveness of global surveillance strategies. Linking surveillance approaches for emerging and neglected endemic zoonoses, with a renewed focus on existing disease problems in developing countries, has the potential to overcome several limitations and to achieve additional health benefits. Poor reporting is a major constraint to the surveillance of both emerging and endemic zoonoses, and several important barriers to reporting can be identified: (i) a lack of tangible benefits when reports are made; (ii) a lack of capacity to enforce regulations; (iii) poor communication among communities, institutions and sectors; and (iv) complexities of the international regulatory environment. Redirecting surveillance efforts to focus on endemic zoonoses in developing countries offers a pragmatic approach that overcomes some of these barriers and provides support in regions where surveillance capacity is currently weakest. In addition, this approach addresses immediate health and development problems, and provides an equitable and sustainable mechanism for building the culture of surveillance and the core capacities that are needed for all zoonotic pathogens, including emerging disease threats
Contextual impacts on industrial processes brought by the digital transformation of manufacturing: a systematic review
The digital transformation of manufacturing (a phenomenon also known as "Industry 4.0" or "Smart Manufacturing") is finding a growing interest both at practitioner and academic levels, but is still in its infancy and needs deeper investigation. Even though current and potential advantages of digital manufacturing are remarkable, in terms of improved efficiency, sustainability, customization, and flexibility, only a limited number of companies has already developed ad hoc strategies necessary to achieve a superior performance. Through a systematic review, this study aims at assessing the current state of the art of the academic literature regarding the paradigm shift occurring in the manufacturing settings, in order to provide definitions as well as point out recurring patterns and gaps to be addressed by future research. For the literature search, the most representative keywords, strict criteria, and classification schemes based on authoritative reference studies were used. The final sample of 156 primary publications was analyzed through a systematic coding process to identify theoretical and methodological approaches, together with other significant elements. This analysis allowed a mapping of the literature based on clusters of critical themes to synthesize the developments of different research streams and provide the most representative picture of its current state. Research areas, insights, and gaps resulting from this analysis contributed to create a schematic research agenda, which clearly indicates the space for future evolutions of the state of knowledge in this field
Nanotechnology and cancer
The biological picture of cancer is rapidly advancing from models built from phenomenological descriptions to network models derived from systems biology, which can capture the evolving pathophysiology of the disease at the molecular level. The translation of this (still academic) picture into a clinically relevant framework can be enabling for the war on cancer, but it is a scientific and technological challenge. In this review, we discuss emerging in vitro diagnostic technologies and therapeutic approaches that are being developed to handle this challenge. Our discussion of in vitro diagnostics is guided by the theme of making large numbers of measurements accurately, sensitively, and at very low cost. We discuss diagnostic approaches based on microfluidics and nanotechnology. We then review the current state of the art of nanoparticle-based therapeutics that have reached the clinic. The goal of the presentation is to identify nanotherapeutic strategies that are designed to increase efficacy while simultaneously minimizing the toxic side effects commonly associated with cancer chemotherapies
Vanadium redox flow batteries: Potentials and challenges of an emerging storage technology
open4noIn this paper an overview of Vanadium Redox Flow Battery technologies, architectures, applications and power electronic interfaces is given. These systems show promising features for energy storage in smart grid applications, where the intermittent power produced by renewable sources must meet strict load requests and economical opportunities. This paper reviews the vanadium-based technology for redox flow batteries and highlights its strengths and weaknesses, outlining the research lines that aim at taking it to full commercial success.openSpagnuolo, Giovanni, Guarnieri, Massimo; Mattavelli, Paolo; Petrone, Giovanni;Guarnieri, Massimo; Mattavelli, Paolo; Petrone, Giovanni; Spagnuolo, Giovann
Arithmetic on a Distributed-Memory Quantum Multicomputer
We evaluate the performance of quantum arithmetic algorithms run on a
distributed quantum computer (a quantum multicomputer). We vary the node
capacity and I/O capabilities, and the network topology. The tradeoff of
choosing between gates executed remotely, through ``teleported gates'' on
entangled pairs of qubits (telegate), versus exchanging the relevant qubits via
quantum teleportation, then executing the algorithm using local gates
(teledata), is examined. We show that the teledata approach performs better,
and that carry-ripple adders perform well when the teleportation block is
decomposed so that the key quantum operations can be parallelized. A node size
of only a few logical qubits performs adequately provided that the nodes have
two transceiver qubits. A linear network topology performs acceptably for a
broad range of system sizes and performance parameters. We therefore recommend
pursuing small, high-I/O bandwidth nodes and a simple network. Such a machine
will run Shor's algorithm for factoring large numbers efficiently.Comment: 24 pages, 10 figures, ACM transactions format. Extended version of
Int. Symp. on Comp. Architecture (ISCA) paper; v2, correct one circuit error,
numerous small changes for clarity, add reference
The future of computing beyond Moore's Law.
Moore's Law is a techno-economic model that has enabled the information technology industry to double the performance and functionality of digital electronics roughly every 2 years within a fixed cost, power and area. Advances in silicon lithography have enabled this exponential miniaturization of electronics, but, as transistors reach atomic scale and fabrication costs continue to rise, the classical technological driver that has underpinned Moore's Law for 50 years is failing and is anticipated to flatten by 2025. This article provides an updated view of what a post-exascale system will look like and the challenges ahead, based on our most recent understanding of technology roadmaps. It also discusses the tapering of historical improvements, and how it affects options available to continue scaling of successors to the first exascale machine. Lastly, this article covers the many different opportunities and strategies available to continue computing performance improvements in the absence of historical technology drivers. This article is part of a discussion meeting issue 'Numerical algorithms for high-performance computational science'
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