4,334 research outputs found

    Identification of Design Principles

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    This report identifies those design principles for a (possibly new) query and transformation language for the Web supporting inference that are considered essential. Based upon these design principles an initial strawman is selected. Scenarios for querying the Semantic Web illustrate the design principles and their reflection in the initial strawman, i.e., a first draft of the query language to be designed and implemented by the REWERSE working group I4

    Dependence relationships between Gene Ontology terms based on TIGR gene product annotations

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    The Gene Ontology is an important tool for the representation and processing of information about gene products and functions. It provides controlled vocabularies for the designations of cellular components, molecular functions, and biological processes used in the annotation of genes and gene products. These constitute three separate ontologies, of cellular components), molecular functions and biological processes, respectively. The question we address here is: how are the terms in these three separate ontologies related to each other? We use statistical methods and formal ontological principles as a first step towards finding answers to this question

    Annotation of SBML Models Through Rule-Based Semantic Integration

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    *Motivation:* The creation of accurate quantitative Systems Biology Markup Language (SBML) models is a time-intensive, manual process often complicated by the many data sources and formats required to annotate even a small and well-scoped model. Ideally, the retrieval and integration of biological knowledge for model annotation should be performed quickly, precisely, and with a minimum of manual effort. Here, we present a method using off-the-shelf semantic web technology which enables this process: the heterogeneous data sources are first syntactically converted into ontologies; these are then aligned to a small domain ontology by applying a rule base. Integrating resources in this way can accommodate multiple formats with different semantics; it provides richly modelled biological knowledge suitable for annotation of SBML models.
*Results:* We demonstrate proof-of-principle for this rule-based mediation with two use cases for SBML model annotation. This was implemented with existing tools, decreasing development time and increasing reusability. This initial work establishes the feasibility of this approach as part of an automated SBML model annotation system.
*Availability:* Detailed information including download and mapping of the ontologies as well as integration results is available from "http://www.cisban.ac.uk/RBM":http://www.cisban.ac.uk/RB

    Leveraging Semantic Web Service Descriptions for Validation by Automated Functional Testing

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    Recent years have seen the utilisation of Semantic Web Service descriptions for automating a wide range of service-related activities, with a primary focus on service discovery, composition, execution and mediation. An important area which so far has received less attention is service validation, whereby advertised services are proven to conform to required behavioural specifications. This paper proposes a method for validation of service-oriented systems through automated functional testing. The method leverages ontology-based and rule-based descriptions of service inputs, outputs, preconditions and effects (IOPE) for constructing a stateful EFSM specification. The specification is subsequently utilised for functional testing and validation using the proven Stream X-machine (SXM) testing methodology. Complete functional test sets are generated automatically at an abstract level and are then applied to concrete Web services, using test drivers created from the Web service descriptions. The testing method comes with completeness guarantees and provides a strong method for validating the behaviour of Web services

    The business process modelling ontology

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    In this paper we describe the Business Process Modelling Ontology (BPMO), which is part of an approach to modelling business processes at the semantic level, integrating knowledge about the organisational context, workflow activities and Semantic Web Services. We harness knowledge representation and reasoning techniques so that business process workflows can: be exposed and shared through semantic descriptions; refer to semantically annotated data and services; incorporate heterogeneous data though semantic mappings; and be queried using a reasoner or inference engine. In this paper we describe our approach and evaluate BPMO through a use case

    Supporting Semantically Enhanced Web Service Discovery for Enterprise Application Integration

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    The availability of sophisticated Web service discovery mechanisms is an essential prerequisite for increasing the levels of efficiency and automation in EAI. In this chapter, we present an approach for developing service registries building on the UDDI standard and offering semantically-enhanced publication and discovery capabilities in order to overcome some of the known limitations of conventional service registries. The approach aspires to promote efficiency in EAI in a number of ways, but primarily by automating the task of evaluating service integrability on the basis of the input and output messages that are defined in the Web serviceā€™s interface. The presented solution combines the use of three technology standards to meet its objectives: OWL-DL, for modelling service characteristics and performing fine-grained service matchmaking via DL reasoning, SAWSDL, for creating semantically annotated descriptions of service interfaces, and UDDI, for storing and retrieving syntactic and semantic information about services and service providers
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