An advanced variant of an interpolatory graphical display algorithm

In this paper an advanced interpolatory graphical display algorithm based on cardinal B-spline functions is provided. It is well-known that B-spline functions are a flexible tool to design various scale rapresentations of a signal. The proposed method allows to display without recursion a function at any desiderable resolution so that only initial data and opportune vectors weight are involved. In this way the structure of the algorithm is independent across the scale and a computational efficiency is reached. In this paper mono and bi-dimensional vectors weight generated by means of centered cubic cardinal B-spline functions have been supplied

A scale-space approach with wavelets to singularity estimation

This paper is concerned with the problem of determining the typical features of a curve when it is observed with noise. It has been shown that one can characterize the Lipschitz singularities of a signal by following the propagation across scales of the modulus maxima of its continuous wavelet transform. A nonparametric approach, based on appropriate thresholding of the empirical wavelet coefficients, is proposed to estimate the wavelet maxima of a signal observed with noise at various scales. In order to identify the singularities of the unknown signal, we introduce a new tool, "the structural intensity", that computes the "density" of the location of the modulus maxima of a wavelet representation along various scales. This approach is shown to be an effective technique for detecting the significant singularities of a signal corrupted by noise and for removing spurious estimates. The asymptotic properties of the resulting estimators are studied and illustrated by simulations. An application to a real data set is also proposed

A Hybrid Approach of Using Wavelets and Fuzzy Clustering for Classifying Multispectral Florescence In Situ Hybridization Images

Multicolor or multiplex fluorescence in situ hybridization (M-FISH) imaging is a recently developed molecular cytogenetic diagnosis technique for rapid visualization of genomic aberrations at the chromosomal level. By the simultaneous use of all 24 human chromosome painting probes, M-FISH imaging facilitates precise identification of complex chromosomal rearrangements that are responsible for cancers and genetic diseases. The current approaches, however, cannot have the precision sufficient for clinical use. The reliability of the technique depends primarily on the accurate pixel-wise classification, that is, assigning each pixel into one of the 24 classes of chromosomes based on its six-channel spectral representations. In the paper we introduce a novel approach to improve the accuracy of pixel-wise classification. The approach is based on the combination of fuzzy clustering and wavelet normalization. Two wavelet-based algorithms are used to reduce redundancies and to correct misalignments between multichannel FISH images. In comparison with conventional algorithms, the wavelet-based approaches offer more advantages such as the adaptive feature selection and accurate image registration. The algorithms have been tested on images from normal cells, showing the improvement in classification accuracy. The increased accuracy of pixel-wise classification will improve the reliability of the M-FISH imaging technique in identifying subtle and cryptic chromosomal abnormalities for cancer diagnosis and genetic disorder research

Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images

The blood vessels and nerve trees consist of tubular objects interconnected into a complex tree- or web-like structure that has a range of structural scale 5 μm diameter capillaries to 3 cm aorta. This large-scale range presents two major problems; one is just making the measurements, and the other is the exponential increase of component numbers with decreasing scale. With the remarkable increase in the volume imaged by, and resolution of, modern day 3D imagers, it is almost impossible to make manual tracking of the complex multiscale parameters from those large image data sets. In addition, the manual tracking is quite subjective and unreliable. We propose a solution for automation of an adaptive nonsupervised system for tracking tubular objects based on multiscale framework and use of Hessian-based object shape detector incorporating National Library of Medicine Insight Segmentation and Registration Toolkit (ITK) image processing libraries

Fast Frequency Estimation by Zero Crossings of Differential Spline Wavelet Transform

Zero crossings or extrema of a wavelet transform constitute important signatures for signal analysis with the advantage of great simplicity. In this paper, we introduce a fast frequency-estimation method based on zero-crossing counting in the transform domain of a family of differential spline wavelets. The resolution and order of the vanishing moments of the chosen wavelets have a close relation with the frequency components of a signal. Theoretical results on estimating the highest and the lowest frequency components are derived, which are particularly useful for frequency estimation of harmonic signals. The results are illustrated with the help of several numerical examples. Finally, we discuss the connection of this approach with other frequency estimation methods, with the high-order level-crossing analysis in statistics, and with the scaling theorem in computer vision.Peer Reviewe

Cardiac motion estimation from medical images: a regularisation framework applied on pairwise image registration displacement fields

Accurate cardiac motion estimation from medical images such as ultrasound is important for clinical evaluation. We present a novel regularisation layer for cardiac motion estimation that will be applied after image registration and demonstrate its effectiveness. The regularisation utilises a spatio-temporal model of motion, b-splines of Fourier, to fit to displacement fields from pairwise image registration. In the process, it enforces spatial and temporal smoothness and consistency, cyclic nature of cardiac motion, and better adherence to the stroke volume of the heart. Flexibility is further given for inclusion of any set of registration displacement fields. The approach gave high accuracy. When applied to human adult Ultrasound data from a Cardiac Motion Analysis Challenge (CMAC), the proposed method is found to have 10% lower tracking error over CMAC participants. Satisfactory cardiac motion estimation is also demonstrated on other data sets, including human fetal echocardiography, chick embryonic heart ultrasound images, and zebrafish embryonic microscope images, with the average Dice coefficient between estimation motion and manual segmentation at 0.82–0.87. The approach of performing regularisation as an add-on layer after the completion of image registration is thus a viable option for cardiac motion estimation that can still have good accuracy. Since motion estimation algorithms are complex, dividing up regularisation and registration can simplify the process and provide flexibility. Further, owing to a large variety of existing registration algorithms, such an approach that is usable on any algorithm may be useful

Multidimensional Wavelets and Computer Vision

This report deals with the construction and the mathematical analysis of multidimensional nonseparable wavelets and their efficient application in computer vision. In the first part, the fundamental principles and ideas of multidimensional wavelet filter design such as the question for the existence of good scaling matrices and sensible design criteria are presented and extended in various directions. Afterwards, the analytical properties of these wavelets are investigated in some detail. It will turn out that they are especially well-suited to represent (discretized) data as well as large classes of operators in a sparse form - a property that directly yields efficient numerical algorithms. The final part of this work is dedicated to the application of the developed methods to the typical computer vision problems of nonlinear image regularization and the computation of optical flow in image sequences. It is demonstrated how the wavelet framework leads to stable and reliable results for these problems of generally ill-posed nature. Furthermore, all the algorithms are of order O(n) leading to fast processing

A Chronology of Interpolation: From Ancient Astronomy to Modern Signal and Image Processing

This paper presents a chronological overview of the developments in interpolation theory, from the earliest times to the present date. It brings out the connections between the results obtained in different ages, thereby putting the techniques currently used in signal and image processing into historical perspective. A summary of the insights and recommendations that follow from relatively recent theoretical as well as experimental studies concludes the presentation