Neutrosophic rule-based prediction system for toxicity effects assessment of biotransformed hepatic drugs

Measuring toxicity is an important step in drug development. However, the current experimental meth- ods which are used to estimate the drug toxicity are expensive and need high computational efforts. Therefore, these methods are not suitable for large-scale evaluation of drug toxicity. As a consequence, there is a high demand to implement computational models that can predict drug toxicity risks. In this paper, we used a dataset that consists of 553 drugs that biotransformed in the liver

A Multi-Tier Knowledge Discovery Info-Structure Using Ensemble Techniques

Fokus utama kami ialah untuk mempelajari keujudan peraturan-peraturan yang ditemui daripada data-data tanpa catatan serta menjana keputusan yang lebih tepat dan muktamad. Our terminal focus is to learn rules instances that have been discovered from unannotated data and generate results with high accuracy

A Multi-Tier Knowledge Discovery Info-Structure Using Ensemble Techniques [QA76.9.D35 S158 2007 f rb].

Fokus utama kami ialah untuk mempelajari keujudan peraturan-peraturan yang ditemui daripada data-data tanpa catatan serta menjana keputusan yang lebih tepat dan muktamad. Ini dilakukan melalui kaedah penghibridan yang merangkumi kedua-dua mekanisma berselia dan tidak berselia. Our terminal focus is to learn rules instances that have been discovered from unannotated data and generate results with high accuracy. This is done via a hybridized methodology which features both supervised and unsupervised techniques. Unannotated data without prior classification information could now be useful as our research has brought new insight to knowledge discovery and learning altogether

Variable precision rough set theory decision support system: With an application to bank rating prediction

This dissertation considers, the Variable Precision Rough Sets (VPRS) model, and its development within a comprehensive software package (decision support system), incorporating methods of re sampling and classifier aggregation. The concept of /-reduct aggregation is introduced, as a novel approach to classifier aggregation within the VPRS framework. The software is applied to the credit rating prediction problem, in particularly, a full exposition of the prediction and classification of Fitch's Individual Bank Strength Ratings (FIBRs), to a number of banks from around the world is presented. The ethos of the developed software was to rely heavily on a simple 'point and click' interface, designed to make a VPRS analysis accessible to an analyst, who is not necessarily an expert in the field of VPRS or decision rule based systems. The development of the software has also benefited from consultations with managers from one of Europe's leading hedge funds, who gave valuable insight, advice and recommendations on what they considered as pertinent issues with regards to data mining, and what they would like to see from a modern data mining system. The elements within the developed software reflect each stage of the knowledge discovery process, namely, pre-processing, feature selection, data mining, interpretation and evaluation. The developed software encompasses three software packages, a pre-processing package incorporating some of the latest pre-processing and feature selection methods a VPRS data mining package, based on a novel "vein graph" interface, which presents the analyst with selectable /-reducts over the domain of / and a third more advanced VPRS data mining package, which essentially automates the vein graph interface for incorporation into a re-sampling environment, and also implements the introduced aggregated /-reduct, developed to optimise and stabilise the predictive accuracy of a set of decision rules induced from the aggregated /-reduct