Development of a Biomimetic Semicircular Canal with MEMS Sensors to Restore Balance

© 2001-2012 IEEE. A third of adults over the age of 50 suffer from chronic impairment of balance, posture, and/or gaze stability due to partial or complete impairment of the sensory cells in the inner ear responsible for these functions. The consequences of impaired balance organ can be dizziness, social withdrawal, and acceleration of the further functional decline. Despite the significant progress in biomedical sensing technologies, current artificial vestibular systems fail to function in practical situations and in very low frequencies. Herein, we introduced a novel biomechanical device that closely mimics the human vestibular system. A microelectromechanical systems (MEMS) flow sensor was first developed to mimic the vestibular haircell sensors. The sensor was then embedded into a three-dimensional (3D) printed semicircular canal and tested at various angular accelerations in the frequency range from 0.5Hz to 1.5Hz. The miniaturized device embedded into a 3D printed model will respond to mechanical deflections and essentially restore the sense of balance in patients with vestibular dysfunctions. The experimental and simulation studies of semicircular canal presented in this work will pave the way for the development of balance sensory system, which could lead to the design of a low-cost and commercially viable medical device with significant health benefits and economic potential

Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 145

This bibliography lists 301 reports, articles, and other documents introduced into the NASA scientific and technical information system in August 1975

Perturbation-based detection and prosthetic correction of vestibulopathic gait

Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, February 2007.Includes bibliographical references.While being able to balance is something most of us take for granted, each year approximately 400,000 Americans are diagnosed with a balance disorder. In order to prevent fall-related injuries due to postural instability, it is important to create both diagnosis techniques so that therapy can be applied before a fall occurs and devices which can aid the balance-impaired population. The aims of this research are twofold: 1) to develop metrics that quantify the locomotor stability of individuals with reduced vestibular function and 2) to assess the capability of a noninvasive vibrotactile balance prosthesis for improving postural and gait stability. The clinical standards of practice for assessing vestibular deficiency include testing postural stability while standing but not during locomotion. This research examines one prospective locomotor-based technique involving the analysis of postural recovery from controlled surface perturbations. The research also investigates the use of a novel wearable vibrotactile sensory substitution device for enhanced postural and locomotor stability. The balance prosthesis is composed of an inertial motion-sensing system mounted on the lower back, a vibrotactile display worn around the torso, and a computer controller.(cont.) It can serve as a permanent or temporary replacement of motion cues, a tool for vestibular rehabilitation, or an additional sensory channel for military troops, pilots, and astronauts. This research demonstrates that well-compensated vestibulopathic patients can be differentiated from young and age-matched controls during over ground locomotion based on step width variability. Prior to this research, unilateral and bilateral vestibulopathic patients donning the vibrotactile balance prosthesis have demonstrated increased postural stability during single-axis support surface perturbations using single-axis sway information. This work shows that multi-directional vibrotactile tilt feedback reduces postural sway during multi-directional support surface perturbations, and has both short- and long-term effects on increasing postural stability. Finally, this research demonstrates for the first time that medial-lateral (M/L) tilt feedback can be used by balance-deficient subjects to reduce factors associated with fall risk (M/L tilt and M/L step width variability) during various locomotor tasks.by Kathleen H. Sienko.Ph.D

Empowering and assisting natural human mobility: The simbiosis walker

This paper presents the complete development of the Simbiosis Smart Walker. The device is equipped with a set of sensor subsystems to acquire user-machine interaction forces and the temporal evolution of user's feet during gait. The authors present an adaptive filtering technique used for the identification and separation of different components found on the human-machine interaction forces. This technique allowed isolating the components related with the navigational commands and developing a Fuzzy logic controller to guide the device. The Smart Walker was clinically validated at the Spinal Cord Injury Hospital of Toledo - Spain, presenting great acceptability by spinal chord injury patients and clinical staf

Modeling the electrical stimulation of peripheral vestibular nerves

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.Includes bibliographical references (p. 137-143).The research conducted for this thesis investigated the theoretical placement of electrodes for a proposed implantable vestibular prosthesis to aid patients suffering from balance related disorders. The most likely sites of stimulation for the first-generation of such a device are the peripheral nerves responsible for transmitting rotational information to the brain. Although stimulation of such nerves has been performed in human and animal patients, little is known about the mechanisms responsible for the eliciting nerve responses. Models of the inferior and superior divisions of peripheral vestibular nerve were created to characterize the stimulus threshold behavior across the parameters of fiber diameter and location within the nerve. Current-distance relations were derived for nerve fibers excited by six commonly used electrode configurations. The threshold relations were used as a guide to determine the electrode configuration and location best-suited to stimulate the inferior vestibular nerve and selectively stimulate the branches of the superior vestibular nerve. The criteria used determine optimal placement included minimum current thresholds, configuration simplicity, and distance to the electrode. For the inferior nerve case, a cathodal stimulus located at a distance of 100 pm or 200 ym from the nerve and driven with a stimulus current of 56 pA or 76 pIA was recommended. For the superior vestibular nerve case we were interested in selectively stimulating each branch, imposing a further criteria to maximize the threshold ratio between stimulation of the respective branches. A transverse dipole electrode configurations was suggested that allowed selective stimulation of either branch. The configuration included a cathode located 300m from Branch 1 and an anode centrally located between both branches.(cont.) When driven with a cathodal stimulus of strength 51 pA, only Branch I was excited, while driving both electrodes with a magnitude of 106 jIA excited only Branch II. The proximity to the facial nerve was considered in the choicesby Ketul M. Parikh.M.Eng

An Evaluation of the Suitability of Commercially Available Sensors for Use in a Virtual Reality Prosthetic Arm Motion Tracking Device

The loss of a hand or arm is a devastating life event that results in many months of healing and challenging rehabilitation. Technology has allowed the development of an electronic replacement for a lost limb but similar advancements in therapy have not occurred. The situation is made more challenging because people with amputations often do not live near specialized rehabilitation centres. As a result, delays in therapy can worsen common complications like nerve pain and joint stiffness. For children born without a limb, poor compliance with the use of their prosthesis leads to delays in therapy and may affect their development. In many parts of the world, amputation rehabilitation does not exist. Fortunately, we live in an age where advances in technology and engineering can help solve these problems. Virtual reality creates a simulated world or environment through computer animation much like what is seen in modern video games. An experienced team of rehabilitation doctors, therapists, engineers and computer scientists are required to realize a system such as this. A person with an amputation will be taught to control objects in the virtual world by wearing a modified electronic prosthesis. Using computers, it will be possible to analyze his or her movements within the virtual world and improve the wearer's skills. The goals of this system include making the system portable and internet compatible so that people living in remote areas can also receive therapy. The novel approach of using virtual reality to rehabilitate people with upper limb amputations will help them return to normal activities by providing modern and appropriate rehabilitation, reducing medical complications, improving motivation (via gaming modules), advancing health care technology and reducing health care costs. The use of virtual reality technology in the field of amputee rehabilitation is in its earliest stages of development world wide. A virtual environment (VE) will facilitate the early rehabilitation of a patient before they are clinically ready to be fitted with an actual prosthesis. In order to create a successful virtual reality rehabilitation system such as this, an accurate method of tracking the arm in real-time is necessary. A linear displacement sensor and a microelectromechanical system (MEMS) inertial measurement unit (IMU) were used to create a device for capturing the motion of a user's movement with the intent that the data provided by the device be used along with a VE as a virtual rehabilitation tool for new upper extremity amputation patients. This thesis focuses on the design and testing of this motion capture device in order to determine the suitability of current commercially available sensing components as used in this system. Success will be defined by the delivery of accurate position and orientation data from the device so that that data can be used in a virtual environment. Test results show that with current MEMS sensors, the error introduced by double integrating acceleration data is too significant to make an IMU an acceptable choice for position tracking. However, the device designed here has proven to be an excellent cable emulator, and would be well suited if used as an orientation tracker

Southwest Research Institute assistance to NASA in biomedical areas of the technology

Significant applications of aerospace technology were achieved. These applications include: a miniaturized, noninvasive system to telemeter electrocardiographic signals of heart transplant patients during their recuperative period as graded situations are introduced; and economical vital signs monitor for use in nursing homes and rehabilitation hospitals to indicate the onset of respiratory arrest; an implantable telemetry system to indicate the onset of the rejection phenomenon in animals undergoing cardiac transplants; an exceptionally accurate current proportional temperature controller for pollution studies; an automatic, atraumatic blood pressure measurement device; materials for protecting burned areas in contact with joint bender splints; a detector to signal the passage of animals by a given point during ecology studies; and special cushioning for use with below-knee amputees to protect the integrity of the skin at the stump/prosthesis interface

An investigation into the utility of wearable sensor derived biofeedback on the motor control of the lumbar spine

Lower back pain (LBP) is a disability that affects a large proportion of the population and treatment for this has been shifting towards a more individualized, patient-centered approach. There has been a recent uptake in the utilization and implementation of wearable sensors that can administer biofeedback in various industrial, clinical, and performance-based settings. The overall aim of this Master’s thesis was to investigate how wearable sensors can be used in a sensorimotor (re)training approach, including how sensory biofeedback from wearable sensors can be used to improve measures of spinal motor control and proprioception. Two complementary research studies were completed to address this overall aim. As a systematic review, Study #1 focused on addressing the lack of consensus surrounding wearable sensor derived biofeedback and spine motor control. The results of this review suggest that haptic/vibrotactile feedback is the most common and that it is administered in an instantaneous real-time manner within most experimental paradigms. Further, study #1 identified clear gaps within the research literature. Specifically, future research would benefit from more clarity regarding study design, and movement instructions, and explicit definitions of biofeedback parameters to enhance reproducibility. The aim of Study #2 was to assess the acute effects of wearable sensor-derived auditory biofeedback on gross lumbar proprioception. To assess this, participants completed a target repositioning protocol, followed by a training period where they were provided with auditory feedback for two of four targets based on a percentage of their lumbar ROM. Results suggest that mid-range targets benefitted most from the acute auditory feedback training. Further, individuals with poorer repositioning abilities in the pre-training assessment showed the greatest improvements from the auditory feedback training. This suggests that auditory biofeedback training may be an effective tool to improve proprioception in those with proprioceptive deficits. Collectively these complimentary research studies will improve the understanding surrounding the ecological utility of wearable sensor derived biofeedback in industrial, clinical, and performance settings to enhance to sensorimotor control of the lumbar region