Advanced sensors technology survey

This project assesses the state-of-the-art in advanced or 'smart' sensors technology for NASA Life Sciences research applications with an emphasis on those sensors with potential applications on the space station freedom (SSF). The objectives are: (1) to conduct literature reviews on relevant advanced sensor technology; (2) to interview various scientists and engineers in industry, academia, and government who are knowledgeable on this topic; (3) to provide viewpoints and opinions regarding the potential applications of this technology on the SSF; and (4) to provide summary charts of relevant technologies and centers where these technologies are being developed

An ultra-fast digital diffuse optical spectroscopic imaging system for neoadjuvant chemotherapy monitoring

Up to 20% of breast cancer patients who undergo presurgical (neoadjuvant) chemotherapy have no response to treatment. Standard-of-care imaging modalities, including MRI, CT, mammography, and ultrasound, measure anatomical features and tumor size that reveal response only after months of treatment. Recently, non-invasive, near-infrared optical markers have shown promise in indicating the efficacy of treatment at the outset of the chemotherapy treatment. For example, frequency domain Diffuse Optical Spectroscopic Imaging (DOSI) can be used to characterize the optical scattering and absorption properties of thick tissue, including breast tumors. These parameters can then be used to calculate tissue concentrations of chromophores, including oxyhemoglobin, deoxyhemoglobin, water, and lipids. Tumors differ in hemoglobin concentration, as compared with healthy background tissue, and changes in hemoglobin concentration during neoadjuvant chemotherapy have been shown to correlate with efficacy of treatment. Using DOSI early in treatment to measure chromophore concentrations may be a powerful tool for guiding neoadjuvant chemotherapy treatment. Previous frequency-domain DOSI systems have been limited by large device footprints, complex electronics, high costs, and slow acquisition speeds, all of which complicate access to patients in the clinical setting. In this work a new digital DOSI (dDOSI) system has been developed, which is relatively inexpensive and compact, allowing for use at the bedside, while providing unprecedented measurement speeds. The system builds on, and significantly advances, previous dDOSI setups developed by our group and, for the first time, utilizes hardware-integrated custom board-level direct digital synthesizers (DDS) and analog to digital converters (ADC) to generate and directly measure signals utilizing undersampling techniques. The dDOSI system takes high-speed optical measurements by utilizing wavelength multiplexing while sweeping through hundreds of modulation frequencies in tens of milliseconds. The new dDOSI system is fast, inexpensive, and compact without compromising accuracy and precision

Spread spectrum techniques for indoor wireless IR communications

Multipath dispersion and fluorescent light interference are two major problems in indoor wireless infrared communications systems. Multipath dispersion introduces intersymhol interference at data rates above 10 Mb/s, while fluorescent light induces severe narrowband interference to baseband modulation schemes commonly used such as OOK and PPM. This article reviews the research into the application of direct sequence spread spectrum techniques to ameliorate these key channel impairments without having to resort to complex signal processing techniques. The inherent properties of a spreading sequence are exploited in order to combat the ISI and narrowband interference. In addition, to reduce the impact of these impairments, the DSSS modulation schemes have strived to be bandwidth-efficient and simple to implement. Three main DSSS waveform techniques have been developed and investigated. These are sequence inverse keying, complementary sequence inverse keying, and M-ary biorthogonal keying (MBOK). The operations of the three systems are explained; their performances were evaluated through simulations and experiments for a number of system parameters, including spreading sequence type and length. By comparison with OOK, our results show that SIK, CSIK, and MBOK are effective against multipath dispersion and fluorescent light interference becausc the penalties incurred on the DSSS schemes are between 0-7 dB, while the penalty on OOK in the same environment is more than 17 dB. The DSSS solution for IR wireless transmission demonstrates that a transmission waveform can he designed to remove the key channel impairments in a wireless IR system

Deep space communication and navigation study. Volume 1 - Summary

Comparison of alternative means for high data rate communication from deep space probes, and deep space navigation by orbiting spacecraf

Advanced deep space communication systems study Final report

Deep space communication system requirements for period 1970 to 198

Application of advanced technology to space automation

Automated operations in space provide the key to optimized mission design and data acquisition at minimum cost for the future. The results of this study strongly accentuate this statement and should provide further incentive for immediate development of specific automtion technology as defined herein. Essential automation technology requirements were identified for future programs. The study was undertaken to address the future role of automation in the space program, the potential benefits to be derived, and the technology efforts that should be directed toward obtaining these benefits