The origin of biological macromolecules on the earth. The hypothesis of inorganic template

Studies about the origin of life are reviewed. The nonrandom organization of organelles is discussed from a structural and functional point of view. After postulating that the origin of biomacromolecules was not a random event, the paper develops the hypothesis that polypeptides and polynucleotides were formed on an inorganic template. Only information-containing structures can pass natural selection and develop through evolution

Quantification and prediction of extreme events in a one-dimensional nonlinear dispersive wave model

The aim of this work is the quantification and prediction of rare events characterized by extreme intensity in nonlinear waves with broad spectra. We consider a one-dimensional non- linear model with deep-water waves dispersion relation, the Majda-McLaughlin-Tabak (MMT) model, in a dynamical regime that is characterized by broadband spectrum and strong non- linear energy transfers during the development of intermittent events with finite-lifetime. To understand the energy transfers that occur during the development of an extreme event we perform a spatially localized analysis of the energy distribution along different wavenumbers by means of the Gabor transform. A stochastic analysis of the Gabor coefficients reveals i) the low-dimensionality of the intermittent structures, ii) the interplay between non-Gaussian statis- tical properties and nonlinear energy transfers between modes, as well as iii) the critical scales (or critical Gabor coefficients) where a critical amount of energy can trigger the formation of an extreme event. We analyze the unstable character of these special localized modes directly through the system equation and show that these intermittent events are due to the interplay of the system nonlinearity, the wave dispersion, and the wave dissipation which mimics wave breaking. These localized instabilities are triggered by random localizations of energy in space, created by the dispersive propagation of low-amplitude waves with random phase. Based on these properties, we design low-dimensional functionals of these Gabor coefficients that allow for the prediction of the extreme event well before the nonlinear interactions begin to occur.Comment: 21 pages, 14 figure

Gamma-based clustering via ordered means with application to gene-expression analysis

Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite catalog of structures, each one representing equality and inequality constraints among latent expected values. Computations depend on the probability that independent gamma-distributed variables attain each of their possible orderings. Each ordering event is equivalent to an event in independent negative-binomial random variables, and this finding guides a dynamic-programming calculation. The structuring of mixture-model components according to constraints among latent means leads to strict concavity of the mixture log likelihood. In addition to its beneficial numerical properties, the clustering method shows promising results in an empirical study.Comment: Published in at http://dx.doi.org/10.1214/10-AOS805 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

Accelerated rogue waves generated by soliton fusion at the advanced stage of supercontinuum formation in photonic crystal fibers

Soliton fusion is a fascinating and delicate phenomenon that manifests itself in optical fibers in case of interaction between co-propagating solitons with small temporal and wavelengths separation. We show that the mechanism of acceleration of trailing soliton by dispersive waves radiated from the preceding one provides necessary conditions for soliton fusion at the advanced stage of supercontinuum generation in photonic crystal fibers. As a result of fusion large intensity robust light structures arise and propagate over significant distances. In presence of small random noise the delicate condition for the effective fusion between solitons can easily be broken, making the fusion induced giant waves a rare statistical event. Thus oblong-shaped giant accelerated waves become excellent candidates for optical rogue waves.Comment: Optics Letters Journal. In pres

Random combinatorial structures: the convergent case

This paper studies the distribution of the component spectrum of combinatorial structures such as uniform random forests, in which the classical generating function for the numbers of (irreducible) elements of the different sizes converges at the radius of convergence; here, this property is expressed in terms of the expectations of independent random variables Zj, j ≥ 1, whose joint distribution, conditional on the event that Σnj=1 jZj = n, gives the distribution of the component spectrum for a random structure of size n. For a large class of such structures, we show that the component spectrum is asymptotically composed of Zj components of small sizes j, j ≥ 1, with the remaining part, of size close to n, being made up of a single, giant component

Grasping asymmetric information in market impacts

The price impact for a single trade is estimated by the immediate response on an event time scale, i.e., the immediate change of midpoint prices before and after a trade. We work out the price impacts across a correlated financial market. We quantify the asymmetries of the distributions and of the market structures of cross-impacts, and find that the impacts across the market are asymmetric and non-random. Using spectral statistics and Shannon entropy, we visualize the asymmetric information in price impacts. Also, we introduce an entropy of impacts to estimate the randomness between stocks. We show that the useful information is encoded in the impacts corresponding to small entropy. The stocks with large number of trades are more likely to impact others, while the less traded stocks have higher probability to be impacted by others