47,571 research outputs found
Qualitative System Identification from Imperfect Data
Experience in the physical sciences suggests that the only realistic means of
understanding complex systems is through the use of mathematical models.
Typically, this has come to mean the identification of quantitative models
expressed as differential equations. Quantitative modelling works best when the
structure of the model (i.e., the form of the equations) is known; and the
primary concern is one of estimating the values of the parameters in the model.
For complex biological systems, the model-structure is rarely known and the
modeler has to deal with both model-identification and parameter-estimation. In
this paper we are concerned with providing automated assistance to the first of
these problems. Specifically, we examine the identification by machine of the
structural relationships between experimentally observed variables. These
relationship will be expressed in the form of qualitative abstractions of a
quantitative model. Such qualitative models may not only provide clues to the
precise quantitative model, but also assist in understanding the essence of
that model. Our position in this paper is that background knowledge
incorporating system modelling principles can be used to constrain effectively
the set of good qualitative models. Utilising the model-identification
framework provided by Inductive Logic Programming (ILP) we present empirical
support for this position using a series of increasingly complex artificial
datasets. The results are obtained with qualitative and quantitative data
subject to varying amounts of noise and different degrees of sparsity. The
results also point to the presence of a set of qualitative states, which we
term kernel subsets, that may be necessary for a qualitative model-learner to
learn correct models. We demonstrate scalability of the method to biological
system modelling by identification of the glycolysis metabolic pathway from
data
Mathematical Thinking Undefended on The Level of The Semester for Professional Mathematics Teacher Candidates
Mathematical thinking skills are very important in mathematics, both to learn math or as learning goals. Thinking skills can be seen from the description given answers in solving mathematical problems faced. Mathematical thinking skills can be seen from the types, levels, and process. Proportionally questions given to students at universities in Indonesia (semester I, III, V, and VII). These questions are a matter of description that belong to the higher-level thinking. Students choose 5 of 8 given problem. Qualitatively, the answers were analyzed by descriptive to see the tendency to think mathematically used in completing the test. The results show that students tend to choose the issues relating to the calculation. They are more use cases, examples and not an example, to evaluate the conjecture and prove to belong to the numeric argumentation. Used mathematical thinking students are very personal (intelligence, interest, and experience), and the situation (problems encountered). Thus, the level of half of the students are not guaranteed and shows the level of mathematical thinking
An immune network approach to learning qualitative models of biological pathways
ACKNOWLEDGMENT GMC is supported by the CRISP project (Combinatorial Responses In Stress Pathways) funded by the BBSRC (BB/F00513X/1) under the Systems Approaches to Biological Research (SABR) Initiative. WP and GMC are also supported by the partnership fund from dot.rural, RCUK Digital Economy research.Postprin
Semi-Quantitative Comparative Analysis And Its Application
SQCA is an implemented technique for the semi-quantitative comparative analysis of dynamical systems. It is both able to deal with incompletely specified models and make precise predictions by exploiting semi-quantitative information in the form of numerical bounds on the variables and functions occuring in the models. The technique has a solid mathematical foundation which facilitates proofs of correctness and convergence properties. SQCA represents the core of a method for the automated prediction of experimental results
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