The detection and classification of blast cell in Leukaemia Acute Promyelocytic Leukaemia (AML M3) blood using simulated annealing and neural networks

This paper was delivered at AIME 2011: 13th Conference on Artifical Intelligence in Medicine.This paper presents a method for the detection and classification of blast cells in M3 with others sub-types using simulated annealing and neural networks. In this paper, we increased our test result from 10 images to 20 images. We performed Hill Climbing, Simulated Annealing and Genetic Algorithms for detecting the blast cells. As a result, simulated annealing is the “best” heuristic search for detecting the leukaemia cells. From the detection, we performed features extraction on the blast cells and we classifying based on M3 and other sub-types using neural networks. We received convincing result which has targeting around 97% in classifying of M3 with other sub-types. Our results are based on real world image data from a Haematology Department.Universiti Sains Islam Malaysia and the Ministry of Higher Education, Malaysi

FORTEST: Formal methods and testing

Formal methods have traditionally been used for specification and development of software. However there are potential benefits for the testing stage as well. The panel session associated with this paper explores the usefulness or otherwise of formal methods in various contexts for improving software testing. A number of different possibilities for the use of formal methods are explored and questions raised. The contributors are all members of the UK FORTEST Network on formal methods and testing. Although the authors generally believe that formal methods are useful in aiding the testing process, this paper is intended to provoke discussion. Dissenters are encouraged to put their views to the panel or individually to the authors

Solving the undirected feedback vertex set problem by local search

An undirected graph consists of a set of vertices and a set of undirected edges between vertices. Such a graph may contain an abundant number of cycles, then a feedback vertex set (FVS) is a set of vertices intersecting with each of these cycles. Constructing a FVS of cardinality approaching the global minimum value is a optimization problem in the nondeterministic polynomial-complete complexity class, therefore it might be extremely difficult for some large graph instances. In this paper we develop a simulated annealing local search algorithm for the undirected FVS problem. By defining an order for the vertices outside the FVS, we replace the global cycle constraints by a set of local vertex constraints on this order. Under these local constraints the cardinality of the focal FVS is then gradually reduced by the simulated annealing dynamical process. We test this heuristic algorithm on large instances of Er\"odos-Renyi random graph and regular random graph, and find that this algorithm is comparable in performance to the belief propagation-guided decimation algorithm.Comment: 6 page