Efficient Parameter Estimation for Information Retrieval Using Black-Box Optimization

open4openCosta A.; Di Buccio E.; Melucci M.; Nannicini G.Costa, A.; Di Buccio, E.; Melucci, M.; Nannicini, G

The Detection of Contradictory Claims in Biomedical Abstracts

Research claims in the biomedical domain are not always consistent, and may even be contradictory. This thesis explores contradictions between research claims in order to determine whether or not it is possible to develop a solution to automate the detection of such phenomena. Such a solution will help decision-makers, including researchers, to alleviate the effects of contradictory claims on their decisions. This study develops two methodologies to construct corpora of contradictions. The first methodology utilises systematic reviews to construct a manually-annotated corpus of contradictions. The second methodology uses a different approach to construct a corpus of contradictions which does not rely on human annotation. This methodology is proposed to overcome the limitations of the manual annotation approach. Moreover, this thesis proposes a pipeline to detect contradictions in abstracts. The pipeline takes a question and a list of research abstracts which may contain answers to it. The output of the pipeline is a list of sentences extracted from abstracts which answer the question, where each sentence is annotated with an assertion value with respect to the question. Claims which feature opposing assertion values are considered as potentially contradictory claims. The research demonstrates that automating the detection of contradictory claims in research abstracts is a feasible problem

Data and Text Mining Techniques for In-Domain and Cross-Domain Applications

In the big data era, a wide amount of data has been generated in different domains, from social media to news feeds, from health care to genomic functionalities. When addressing a problem, we usually need to harness multiple disparate datasets. Data from different domains may follow different modalities, each of which has a different representation, distribution, scale and density. For example, text is usually represented as discrete sparse word count vectors, whereas an image is represented by pixel intensities, and so on. Nowadays plenty of Data Mining and Machine Learning techniques are proposed in literature, which have already achieved significant success in many knowledge engineering areas, including classification, regression and clustering. Anyway some challenging issues remain when tackling a new problem: how to represent the problem? What approach is better to use among the huge quantity of possibilities? What is the information to be used in the Machine Learning task and how to represent it? There exist any different domains from which borrow knowledge? This dissertation proposes some possible representation approaches for problems in different domains, from text mining to genomic analysis. In particular, one of the major contributions is a different way to represent a classical classification problem: instead of using an instance related to each object (a document, or a gene, or a social post, etc.) to be classified, it is proposed to use a pair of objects or a pair object-class, using the relationship between them as label. The application of this approach is tested on both flat and hierarchical text categorization datasets, where it potentially allows the efficient addition of new categories during classification. Furthermore, the same idea is used to extract conversational threads from an unregulated pool of messages and also to classify the biomedical literature based on the genomic features treated