19,479 research outputs found

    XML in Motion from Genome to Drug

    Get PDF
    Information technology (IT) has emerged as a central to the solution of contemporary genomics and drug discovery problems. Researchers involved in genomics, proteomics, transcriptional profiling, high throughput structure determination, and in other sub-disciplines of bioinformatics have direct impact on this IT revolution. As the full genome sequences of many species, data from structural genomics, micro-arrays, and proteomics became available, integration of these data to a common platform require sophisticated bioinformatics tools. Organizing these data into knowledgeable databases and developing appropriate software tools for analyzing the same are going to be major challenges. XML (eXtensible Markup Language) forms the backbone of biological data representation and exchange over the internet, enabling researchers to aggregate data from various heterogeneous data resources. The present article covers a comprehensive idea of the integration of XML on particular type of biological databases mainly dealing with sequence-structure-function relationship and its application towards drug discovery. This e-medical science approach should be applied to other scientific domains and the latest trend in semantic web applications is also highlighted

    Integrating sensor streams in pHealth networks

    Get PDF
    Personal Health (pHealth) sensor networks are generally used to monitor the wellbeing of both athletes and the general public to inform health specialists of future and often serious ailments. The problem facing these domain experts is the scale and quality of data they must search in order to extract meaningful results. By using peer-to-peer sensor architectures and a mechanism for reducing the search space, we can, to some extent, address the scalability issue. However, synchronisation and normalisation of distributed sensor streams remains a problem in many networks. In the case of pHealth sensor networks, it is crucial for experts to align multiple sensor readings before query or data mining activities can take place. This paper presents a system for clustering and synchronising sensor streams in preparation for user queries

    Capturing personal health data from wearable sensors

    Get PDF
    Recently, there has been a significant growth in pervasive computing and ubiquitous sensing which strives to develop and deploy sensing technology all around us. We are also seeing the emergence of applications such as environmental and personal health monitoring to leverage data from a physical world. Most of the developments in this area have been concerned with either developing the sensing technologies, or the infrastructure (middleware) to gather this data and the issues which have been addressed include power consumption on the devices, security of data transmission, networking challenges in gathering and storing the data and fault tolerance in the event of network and/or device failure. Research is focusing on harvesting and managing data and providing query capabilities

    State-of-the-art on evolution and reactivity

    Get PDF
    This report starts by, in Chapter 1, outlining aspects of querying and updating resources on the Web and on the Semantic Web, including the development of query and update languages to be carried out within the Rewerse project. From this outline, it becomes clear that several existing research areas and topics are of interest for this work in Rewerse. In the remainder of this report we further present state of the art surveys in a selection of such areas and topics. More precisely: in Chapter 2 we give an overview of logics for reasoning about state change and updates; Chapter 3 is devoted to briefly describing existing update languages for the Web, and also for updating logic programs; in Chapter 4 event-condition-action rules, both in the context of active database systems and in the context of semistructured data, are surveyed; in Chapter 5 we give an overview of some relevant rule-based agents frameworks

    Semantic Query Reformulation in Social PDMS

    Full text link
    We consider social peer-to-peer data management systems (PDMS), where each peer maintains both semantic mappings between its schema and some acquaintances, and social links with peer friends. In this context, reformulating a query from a peer's schema into other peer's schemas is a hard problem, as it may generate as many rewritings as the set of mappings from that peer to the outside and transitively on, by eventually traversing the entire network. However, not all the obtained rewritings are relevant to a given query. In this paper, we address this problem by inspecting semantic mappings and social links to find only relevant rewritings. We propose a new notion of 'relevance' of a query with respect to a mapping, and, based on this notion, a new semantic query reformulation approach for social PDMS, which achieves great accuracy and flexibility. To find rapidly the most interesting mappings, we combine several techniques: (i) social links are expressed as FOAF (Friend of a Friend) links to characterize peer's friendship and compact mapping summaries are used to obtain mapping descriptions; (ii) local semantic views are special views that contain information about external mappings; and (iii) gossiping techniques improve the search of relevant mappings. Our experimental evaluation, based on a prototype on top of PeerSim and a simulated network demonstrate that our solution yields greater recall, compared to traditional query translation approaches proposed in the literature.Comment: 29 pages, 8 figures, query rewriting in PDM

    Proof-of-Concept Application - Annual Report Year 1

    Get PDF
    In this document the Cat-COVITE Application for use in the CATNETS Project is introduced and motivated. Furthermore an introduction to the catallactic middleware and Web Services Agreement (WS-Agreement) concepts is given as a basis for the future work. Requirements for the application of Cat-COVITE with in catallactic systems are analysed. Finally the integration of the Cat-COVITE application and the catallactic middleware is described. --Grid Computing

    Analysis of current middleware used in peer-to-peer and grid implementations for enhancement by catallactic mechanisms

    Get PDF
    This deliverable describes the work done in task 3.1, Middleware analysis: Analysis of current middleware used in peer-to-peer and grid implementations for enhancement by catallactic mechanisms from work package 3, Middleware Implementation. The document is divided in four parts: The introduction with application scenarios and middleware requirements, Catnets middleware architecture, evaluation of existing middleware toolkits, and conclusions. -- Die Arbeit definiert Anforderungen an Grid und Peer-to-Peer Middleware Architekturen und analysiert diese auf ihre Eignung für die prototypische Umsetzung der Katallaxie. Eine Middleware-Architektur für die Umsetzung der Katallaxie in Application Layer Netzwerken wird vorgestellt.Grid Computing

    A Taxonomy of Workflow Management Systems for Grid Computing

    Full text link
    With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources. Such application scenarios require means for composing and executing complex workflows. Therefore, many efforts have been made towards the development of workflow management systems for Grid computing. In this paper, we propose a taxonomy that characterizes and classifies various approaches for building and executing workflows on Grids. We also survey several representative Grid workflow systems developed by various projects world-wide to demonstrate the comprehensiveness of the taxonomy. The taxonomy not only highlights the design and engineering similarities and differences of state-of-the-art in Grid workflow systems, but also identifies the areas that need further research.Comment: 29 pages, 15 figure
    corecore