Bone sarcoma cumulative tumor rates in patients injected with 224Ra

Auf Grund eines Druckfehlers sind die Seiten 28-29 in der Druckvorlage nicht vorhanden

Biodiversity in drinking water distribution systems:a brief review

In drinking water distribution systems, three groups of living organisms are usually found in the biofilm and circulating water: heterotrophic bacteria, free-living protozoa, and macro-invertebrates. Indirect evidence suggests that protozoa grazing in distribution systems can partially eliminate biomass production and accidental microbiological pollution. This paper examines the biodiversit in drinking water distribution systems

Étude sur Les Perceptions et les Attentes des Professionnels de Santé, des Bénévoles et des Familles des Malades dans le Cadre de la Prise en Charge des Soins Palliatifs

This qualitative study, conducted in three metropolitan areas, Champagne Ardenne, Ile-de-France, and Languedoc-Roussillon explores current palliative care practices in 37 facilities, both for dependent elderly (nursing homes) and for adults and children with severe disabilities (MAS and IME). The study confronts the viewpoints of the different actors that revolve around a patient: doctors, nurses and other health professionals (physiotherapists, occupational therapists, psychologists, etc.), relatives, volunteers and patients themselves. 40 cases of sick children and adults were observed. From the analysis of the interviews, it appears that the palliative approach is still not fully adopted by teams that are reluctant to deal with the end of life and postpone the most difficult cases. Among the priorities to be developed are: the harmonization of the initial training of caregivers and ongoing training and the mobilization of specialist palliative care that could better support and assist caregivers in this sector

An amphitropic cAMP-binding protein in yeast mitochondria

ABSTRACT: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol. The stearic acid label is removed by phospholipase D whereupon the protein with the retained inositol label is released from the membrane. This protein is a cAMP receptor of the yeast Saccharomyces cereuisiae and tightly associated with the inner mitochondrial membrane. However, it is converted into a soluble form during incubation of isolated mitochondria with Ca2+ and phospholipid (or lipid derivatives). This transition requires the action of a proteinaceous, N-ethylmaleimide-sensitive component of the intermembrane space and is accompanied by a decrease in the lipophilicity of the cAMP receptor. We propose that the component of the intermembrane space triggers the amphitropic behavior of the mitochondrial lipid-modified CAMP-binding protein through a phospholipase activity. Only in recent years specific fatty acids have been recog-nized to play important roles in the association of proteins with membranes. Both noncovalent and covalent interactions be-tween fatty acids and proteins have been reported. Among the latter are GTP-binding proteins (Molenaar et al., 1988)

Cavernomatose cérébrale sporadique révélée par une crise convulsive: à propos d’un cas

La cavernomatose cérébrale est une pathologie rare pouvant être sporadique ou familiale autosomique dominante. Elle est caractérisée par la présence de cavernomes multiples du système nerveux central. Souvent asymptomatique, la pathologie peut se révéler par des symptômes variés comme l’hémorragie cérébro-méningée, les céphalées ou l’épilepsie. Nous rapportons un cas de cavernomatose cérébrale sporadique chez un patient de 55 ans sans antécédent pathologique particulier révélé par une crise d’épilepsie. A travers cette observation et une revue de la littérature, nous faisons le point sur les aspects cliniques et radiologiques (scanner et IRM) de cette pathologie