252 research outputs found
Ontology-Driven Search and Triage: Design of a Web-Based Visual Interface for MEDLINE
Background: Diverse users need to search health and medical literature to satisfy open-ended goals such as making evidence-based decisions and updating their knowledge. However, doing so is challenging due to at least two major difficulties: (1) articulating information needs using accurate vocabulary and (2) dealing with large document sets returned from searches. Common search interfaces such as PubMed do not provide adequate support for exploratory search tasks.
Objective: Our objective was to improve support for exploratory search tasks by combining two strategies in the design of an interactive visual interface by (1) using a formal ontology to help users build domain-specific knowledge and vocabulary and (2) providing multi-stage triaging support to help mitigate the information overload problem.
Methods: We developed a Web-based tool, Ontology-Driven Visual Search and Triage Interface for MEDLINE (OVERT-MED), to test our design ideas. We implemented a custom searchable index of MEDLINE, which comprises approximately 25 million document citations. We chose a popular biomedical ontology, the Human Phenotype Ontology (HPO), to test our solution to the vocabulary problem. We implemented multistage triaging support in OVERT-MED, with the aid of interactive visualization techniques, to help users deal with large document sets returned from searches.
Results: Formative evaluation suggests that the design features in OVERT-MED are helpful in addressing the two major difficulties described above. Using a formal ontology seems to help users articulate their information needs with more accurate vocabulary. In addition, multistage triaging combined with interactive visualizations shows promise in mitigating the information overload problem.
Conclusions: Our strategies appear to be valuable in addressing the two major problems in exploratory search. Although we tested OVERT-MED with a particular ontology and document collection, we anticipate that our strategies can be transferred successfully to other contexts
Integrating Medical Ontology and Pseudo Relevance Feedback For Medical Document Retrieval
The purpose of this thesis is to undertake and improve the accuracy of locating the relevant documents from a large amount of Electronic Medical Data (EMD). The unique goal of this research is to propose a new idea for using medical ontology to find an easy and more reliable approach for patients to have a better understanding of their diseases and also help doctors to find and further improve the possible methods of diagnosis and treatments. The empirical studies were based on the dataset provided by CLEF focused on health care data. In this research, I have used Information Retrieval to find and obtain relevant information within the large amount of data sets provided by CLEF. I then used ranking functionality on the Terrier platform to calculate and evaluate the matching documents in the collection of data sets. BM25 was used as the base normalization method to retrieve the results and Pseudo Relevance Feedback weighting model to retrieve the information regarding patients health history and medical records in order to find more accurate results. I then used Unified Medical Language System to develop indexing of the queries while searching on the Internet and looking for health related documents. UMLS software was actually used to link the computer system with the health and biomedical terms and vocabularies into classify tools; it works as a dictionary for the patients by translating the medical terms. Later I would like to work on using medical ontology to create a relationship between the documents regarding the medical data and my retrieved results
Automated MeSH Term Suggestion for Effective Query Formulation in Systematic Reviews Literature Search
High-quality medical systematic reviews require comprehensive literature
searches to ensure the recommendations and outcomes are sufficiently reliable.
Indeed, searching for relevant medical literature is a key phase in
constructing systematic reviews and often involves domain (medical researchers)
and search (information specialists) experts in developing the search queries.
Queries in this context are highly complex, based on Boolean logic, include
free-text terms and index terms from standardised terminologies (e.g., the
Medical Subject Headings (MeSH) thesaurus), and are difficult and
time-consuming to build. The use of MeSH terms, in particular, has been shown
to improve the quality of the search results. However, identifying the correct
MeSH terms to include in a query is difficult: information experts are often
unfamiliar with the MeSH database and unsure about the appropriateness of MeSH
terms for a query. Naturally, the full value of the MeSH terminology is often
not fully exploited. This article investigates methods to suggest MeSH terms
based on an initial Boolean query that includes only free-text terms. In this
context, we devise lexical and pre-trained language models based methods. These
methods promise to automatically identify highly effective MeSH terms for
inclusion in a systematic review query. Our study contributes an empirical
evaluation of several MeSH term suggestion methods. We further contribute an
extensive analysis of MeSH term suggestions for each method and how these
suggestions impact the effectiveness of Boolean queries.Comment: This paper is currently in submission with Intelligent Systems with
Applications Journal Technology-Assisted Review Systems Special issue and is
under peer review. arXiv admin note: text overlap with arXiv:2112.0027
GRAPHENE: A Precise Biomedical Literature Retrieval Engine with Graph Augmented Deep Learning and External Knowledge Empowerment
Effective biomedical literature retrieval (BLR) plays a central role in
precision medicine informatics. In this paper, we propose GRAPHENE, which is a
deep learning based framework for precise BLR. GRAPHENE consists of three main
different modules 1) graph-augmented document representation learning; 2) query
expansion and representation learning and 3) learning to rank biomedical
articles. The graph-augmented document representation learning module
constructs a document-concept graph containing biomedical concept nodes and
document nodes so that global biomedical related concept from external
knowledge source can be captured, which is further connected to a BiLSTM so
both local and global topics can be explored. Query expansion and
representation learning module expands the query with abbreviations and
different names, and then builds a CNN-based model to convolve the expanded
query and obtain a vector representation for each query. Learning to rank
minimizes a ranking loss between biomedical articles with the query to learn
the retrieval function. Experimental results on applying our system to TREC
Precision Medicine track data are provided to demonstrate its effectiveness.Comment: CIKM 201
Query expansion using medical information extraction for improving information retrieval in French medical domain
Many users’ queries contain references to named entities, and this is particularly true in the medical field. Doctors express their information needs using medical entities as they are elements rich with information that helps to better target the relevant documents. At the same time, many resources have been recognized as a large container of medical entities and relationships between them such as clinical reports; which are medical texts written by doctors. In this paper, we present a query expansion method that uses medical entities and their semantic relations in the query context based on an external resource in OWL. The goal of this method is to evaluate the effectiveness of an information retrieval system to support doctors in accessing easily relevant information. Experiments on a collection of real clinical reports show that our approach reveals interesting improvements in precision, recall and MAP in medical information retrieval
The Ensemble MESH-Term Query Expansion Models Using Multiple LDA Topic Models and ANN Classifiers in Health Information Retrieval
Information retrieval in the health field has several challenges. Health information terminology is difficult for consumers (laypeople) to understand. Formulating a query with professional terms is not easy for consumers because health-related terms are more familiar to health professionals. If health terms related to a query are automatically added, it would help consumers to find relevant information. The proposed query expansion (QE) models show how to expand a query using MeSH (Medical Subject Headings) terms. The documents were represented by MeSH terms (i.e. Bag-of-MeSH), which were included in the full-text articles. And then the MeSH terms were used to generate LDA (Latent Dirichlet Analysis) topic models. A query and the top k retrieved documents were used to find MeSH terms as topic words related to the query.
LDA topic words were filtered by 1) threshold values of topic probability (TP) and word probability (WP) or 2) an ANN (Artificial Neural Network) classifier. Threshold values were effective in an LDA model with a specific number of topics to increase IR performance in terms of infAP (inferred Average Precision) and infNDCG (inferred Normalized Discounted Cumulative Gain), which are common IR metrics for large data collections with incomplete judgments. The top k words were chosen by the word score based on (TP *WP) and retrieved document ranking in an LDA model with specific thresholds. The QE model with specific thresholds for TP and WP showed improved mean infAP and infNDCG scores in an LDA model, comparing with the baseline result. However, the threshold values optimized for a particular LDA model did not perform well in other LDA models with different numbers of topics.
An ANN classifier was employed to overcome the weakness of the QE model depending on LDA thresholds by automatically categorizing MeSH terms (positive/negative/neutral) for QE. ANN classifiers were trained on word features related to the LDA model and collection. Two types of QE models (WSW & PWS) using an LDA model and an ANN classifier were proposed: 1) Word Score Weighting (WSW) where the probability of being a positive/negative/neutral word was used to weight the original word score, and 2) Positive Word Selection (PWS) where positive words were identified by the ANN classifier. Forty WSW models showed better average mean infAP and infNDCG scores than the PWS models when the top 7 words were selected for QE. Both approaches based on a binary ANN classifier were effective in increasing infAP and infNDCG, statistically, significantly, compared with the scores of the baseline run. A 3-class classifier performed worse than the binary classifier.
The proposed ensemble QE models integrated multiple ANN classifiers with multiple LDA models. Ensemble QE models combined multiple WSW/PWS models and one or multiple classifiers. Multiple classifiers were more effective in selecting relevant words for QE than one classifier. In ensemble QE (WSW/PWS) models, the top k words added to the original queries were effective to increase infAP and infNDCG scores. The ensemble QE model (WSW) using three classifiers showed statistically significant improvements for infAP and infNDCG in the mean scores for 30 queries when the top 3 words were added. The ensemble QE model (PWS) using four classifiers showed statistically significant improvements for 30 queries in the mean infAP and infNDCG scores
MiSearch adaptive pubMed search tool
Summary: MiSearch is an adaptive biomedical literature search tool that ranks citations based on a statistical model for the likelihood that a user will choose to view them. Citation selections are automatically acquired during browsing and used to dynamically update a likelihood model that includes authorship, journal and PubMed indexing information. The user can optionally elect to include or exclude specific features and vary the importance of timeliness in the ranking
- …