63,442 research outputs found
Learner-centred Accessibility for Interoperable Web-based Educational Systems
This paper describes the need for an information model and specifications that support a new strategy for delivering
accessible computer-based resources to learners based on their specific needs and preferences in the circumstances in which they are operating. The strategy augments the universal accessibility of resources model to enable systems to focus on individual learners and their particular accessibility needs and preferences. A set of specifications known as the AccessForAll specifications is proposed
Towards a semantic modeling of learners for social networks
The Friend of a Friend (FOAF) ontology is a vocabulary for mapping social networks. In this paper we propose an extension to FOAF in order to allow it to model learners and their social networks. We analyse FOAF alongside different learner modeling standards and specifications, and based on this analysis we introduce a taxonomy of the different features found in those models. We then compare the learner models and FOAF against the taxonomy to see how their characteristics have been shaped by their purpose. Based on this we propose extensions to FOAF in order to produce a learner model that is capable of forming the basis of a semantic social network.<br/
DNA folding: structural and mechanical properties of the two-angle model for chromatin
We present a theoretical analysis of the structural and mechanical properties
of the 30-nm chromatin fiber. Our study is based on the two-angle model
introduced by Woodcock et al. (Woodcock, C. L., S. A. Grigoryev, R. A.
Horowitz, and N. Whitaker. 1993. PNAS 90:9021-9025) that describes the
chromatin fiber geometry in terms of the entry-exit angle of the nucleosomal
DNA and the rotational setting of the neighboring nucleosomes with respect to
each other. We explore analytically the different structures that arise from
this building principle, and demonstrate that the geometry with the highest
density is close to the one found in native chromatin fibers under
physiological conditions. On the basis of this model we calculate mechanical
properties of the fiber under stretching. We obtain expressions for the
stress-strain characteristics which show good agreement with the results of
recent stretching experiments (Cui, Y., and C. Bustamante. 2000. PNAS
97:127-132) and computer simulations (Katritch, V., C. Bustamante, and W. K.
Olson. 2000. J. Mol. Biol. 295:29-40), and which provide simple physical
insights into correlations between the structural and elastic properties of
chromatin.Comment: 23 pages, 6 figures, to be published in Biophys.
Reformulating Space Syntax: The Automatic Definition and Generation of Axial Lines and Axial Maps
Space syntax is a technique for measuring the relative accessibility of different locations in a spatial system which has been loosely partitioned into convex spaces.These spaces are approximated by straight lines, called axial lines, and the topological graph associated with their intersection is used to generate indices of distance, called integration, which are then used as proxies for accessibility. The most controversial problem in applying the technique involves the definition of these lines. There is no unique method for their generation, hence different users generate different sets of lines for the same application. In this paper, we explore this problem, arguing that to make progress, there need to be unambiguous, agreed procedures for generating such maps. The methods we suggest for generating such lines depend on defining viewsheds, called isovists, which can be approximated by their maximum diameters,these lengths being used to form axial maps similar to those used in space syntax. We propose a generic algorithm for sorting isovists according to various measures,approximating them by their diameters and using the axial map as a summary of the extent to which isovists overlap (intersect) and are accessible to one another. We examine the fields created by these viewsheds and the statistical properties of the maps created. We demonstrate our techniques for the small French town of Gassin used originally by Hillier and Hanson (1984) to illustrate the theory, exploring different criteria for sorting isovists, and different axial maps generated by changing the scale of resolution. This paper throws up as many problems as it solves but we believe it points the way to firmer foundations for space syntax
On Sub-Propositional Fragments of Modal Logic
In this paper, we consider the well-known modal logics ,
, , and , and we study some of their
sub-propositional fragments, namely the classical Horn fragment, the Krom
fragment, the so-called core fragment, defined as the intersection of the Horn
and the Krom fragments, plus their sub-fragments obtained by limiting the use
of boxes and diamonds in clauses. We focus, first, on the relative expressive
power of such languages: we introduce a suitable measure of expressive power,
and we obtain a complex hierarchy that encompasses all fragments of the
considered logics. Then, after observing the low expressive power, in
particular, of the Horn fragments without diamonds, we study the computational
complexity of their satisfiability problem, proving that, in general, it
becomes polynomial
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