Examining of the Effects of Employees on Work Stress, Role Conflict and Job Insecurity on Organizational Culture

Perceived work stress, It is stated that employees are psychologically disturbed and intensely threatening their health at their busy working tempo. Employees with a high degree of stress in the face of excessive workloads may experience burnout and intention to quit. Employees experiencing job insecurity cannot show their real performance and cannot get the efficiency they want from employees because they do not see themselves permanently in their organizations. However, they cannot achieve the desired efficiency due to the fact that employees who have a role conflict must fulfill more than one workload. Employees who are satisfied with their organizations are able to adopt organizational culture and develop their organizational skills such as planning and problem solving. Within the scope of the aim of the research, a survey was conducted with 350 employees. Some of the analyzes were performed using SPSS 25 Program and some of them were performed with AMOS program. Factor analysis and reliability analysis were applied to the questions using Likert scale. The results of factor analysis were checked by confirmatory factor analysis in AMOS. Correlation analysis was used to examine the relationships between variables, and regression analysis was used to test hypotheses

Consideration of the novel psychoactive substances (‘legal highs’)

Original report can be found at: http://www.homeoffice.gov.uk/ Crown Copyright, the Advisory Council/ The Home Office. This work is published under an open government license.The Advisory Council on the Misuse of Drugs (ACMD) committed to providing the Government with advice on novel psychoactive substances (often colloquially termed „legal highs‟). This is a relatively recent phenomenon, exemplified by the drug known as mephedrone. The actions by the ACMD and subsequently by the Government on this drug have gone some way to reducing the potential harms caused by this substance. However, there is more that can be done. The advent of novel psychoactive substances has changed the face of the drug scene remarkably and with rapidity. The range of substances now available, their lack of consistency and the potential harms users are exposed to are now complex and multi-faceted. In light of this we have pleasure in enclosing the Council‟s report. This report provides advice on high level issues that ACMD believe the Government should give careful consideration to in addressing legally available psychoactive substances. The report does not purport to provide a single solution to the problem, but rather a number of practicable options that, in combination, seek to tackle the on-going sale, supply and consequential harms. It is important that the Government recognises that each and every department, that has a locus of responsibility in drug issues should both take personal ownership and share collective responsibility of the recommendations in this report. Tackling the issues that are raised by novel psychoactive substances requires a co-ordination of efforts that can only be realised by a strategic and co-operative approach. The ACMD has identified lead departments for each of the recommendations that should assist and guide the Government in this aim. The ACMD provides key recommendations in this report on legislation, public health, education and research. The key legislative measures are primarily concerned with tightening the enforcement of existing legislation and moving the responsibility for the supply of novel psychoactive substances to the vendors, such that the burden of proof falls to them. The ACMD believe it is for vendors to prove that such substances are neither analogues of current medicines nor products harmful to consumers in their intended form. The ACMD also makes key recommendations around public awareness from local to international initiatives.Final Published versio

The Effect of Word of Mouth on Brand Image of a Popular Indonesian Donut Brand

A Brand must innovate to create a positive impression of consumers. When a consumer feels happy and satisfied with a product, the emotional impact will encourage loyalty and positive word of mouth will increase. The purpose of this research is to know how big influence of word of mouth to brand image of J.CO Donuts & Coffee. The independent variable (X) in this research is word of mouth and the dependent variable (Y) is brand image. This research uses quantitative method with descriptive and causal research type. This research was conducted on 75 respondents and used simple linear regression analysis and data processing using SPSS version 21. Based on the results of hypothesis testing, word of mouth has an influence on brand image J.CO. The results of determination coefficient word of mouth influence to brand image by 46,7%.      Keywords: brand image, word of mouth, marketing, business administratio

The Effect of Squid Extract (Loligo SP) on TNF-α and TGF-β1 Serum Levels During Wound Healing in Streptozotocin-induced Diabetic Rats

Background: Diabetes Mellitus is a chronic disease characterised by elevated levels of blood glucose known as hyperglycaemia. Diabetes is due to impaired insulin action in the metabolism of glucose and can result in impaired wound healing. Excessive production of pro-inflammatory cytokines, an increased number of macrophages and neutrophils, and decreased levels of transforming growth factor - beta 1 (TGF-β1) serum can be characteristic of impaired wound healing. This study aims to determine the effects of squid extract on certain wound parameters such as levels of tumour necrosis factor - alpha (TNF-α), and TGF-β1 serum and the number of macrophages and neutrophils. Methods: This was a post-test only, randomized controlled group study that was conducted on male Wistar rats. Experimental animals were divided into 6 groups; (1) normal wound with standard diet, (2) diabetic wound with standard diet, (3) diabetic wound with chitosan supplement, (4) diabetic wound given squid extract orally once a day, (5) diabetic wound given squid extract orally twice a day, and (6) diabetic wound given squid extract orally once every two days. Levels of TNF-α and TGF-β1 serum were observed using Enzyme-Linked Immunosorbent Assay. Haematocylin and eosin staining was used to observed macrophage and neutrophil counts. All data was analysed statistically by one-way analysis of variance. Results: TNF-α serum levels showed a significant decrease (p < 0.05) in subjects that received squid extract orally once every two days. The mean levels of TGF-β1 showed no significant differences. The mean number of macrophage cells showed a significant decrease (p < 0.05) in all treatment groups. The mean number of neutrophil cells also showed significant decrease (p < 0.05) in all treatment groups. Conclusions: Squid extract is effective in lowering the TNF-α serum levels and the number of macrophages and neutrophils cells in Wistar rats. However, there were insignificant findings on increasing levels of TGF-β1 serum. This data suggests that squid extract is most effective during the inflammatory phase of wound healing which takes places about 2-4 days after wound creation

On the estimation of the persistence exponent for a fractionally integrated brownian motion by numerical simulations

For a fractionally integrated Brownian motion (FIBM) of order alpha is an element of (0, 1], X-alpha(t), we investigate the decaying rate of P(tau(alpha)(S) > t) as t -> +infinity, where tau(alpha)(S) = inf{t > 0 : X-alpha(t) >= S} is the first-passage time (FPT) of X-alpha(t) through the barrier S > 0. Precisely, we study the so-called persistent exponent theta = theta(alpha) of the FPT tail, such that P(tau(alpha)(S) > t) = t(-theta+o(1)), as t -> +infinity, and by means of numerical simulation of long enough trajectories of the process X-alpha(t), we are able to estimate theta(alpha) and to show that it is a non-increasing function of alpha is an element of (0, 1], with 1/4 <= theta(alpha) <= 1/2. In particular, we are able to validate numerically a new conjecture about the analytical expression of the function theta = theta(alpha), for alpha is an element of (0, 1]. Such a numerical validation is carried out in two ways: in the first one, we estimate theta(alpha), by using the simulated FPT density, obtained for any alpha is an element of (0, 1]; in the second one, we estimate the persistent exponent by directly calculating P(max(0)<= s <= tX(alpha)(s) < 1). Both ways confirm our conclusions within the limit of numerical approximation. Finally, we investigate the self-similarity property of X-alpha(t) and we find the upper bound of its covariance function

The Impact of Open Selection on the Number of Corruption Cases in High Leadership Positions (JPT) in Local Governments in Indonesia

This study aims to explain the impact of implementing open selection on the amount of corruption in local government JPT in Indonesia. Using the difference-in-differences-in-differences (DDD) approach, this study analyzes panel data on JPT corruption in Indonesia that have been inkracht handled by the Corruption Eradication Commission (KPK) in the period 2009-2019. The results of theoretical studies and previous research have given rise to the hypothesis that the implementation of open selection has a positive impact on reducing JPT corruption cases in local governments in Indonesia. This study found that the implementation of open selection can reduce the number of corruption cases by -0.892% and significantly at the 10% alpha level in regions with high total capital expenditures. This finding demonstrates the positive impact of open selection on JPT corruption cases and thus supports previous studies on the positive impact of implementing a merit system, in particular open selection on the number of JPT corruption cases in regions with high total spending. In addition, to strengthen the research results by adding case studies and in-depth interviews with KASN and ICW. It was found that it greatly influenced the implementation of open selection. It is the high political costs in the regions that are the main cause that causes corruption of governors, mayors, and regents followed by regional officials to continue to occur