27,122 research outputs found

    Coverage Protocols for Wireless Sensor Networks: Review and Future Directions

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    The coverage problem in wireless sensor networks (WSNs) can be generally defined as a measure of how effectively a network field is monitored by its sensor nodes. This problem has attracted a lot of interest over the years and as a result, many coverage protocols were proposed. In this survey, we first propose a taxonomy for classifying coverage protocols in WSNs. Then, we classify the coverage protocols into three categories (i.e. coverage aware deployment protocols, sleep scheduling protocols for flat networks, and cluster-based sleep scheduling protocols) based on the network stage where the coverage is optimized. For each category, relevant protocols are thoroughly reviewed and classified based on the adopted coverage techniques. Finally, we discuss open issues (and recommend future directions to resolve them) associated with the design of realistic coverage protocols. Issues such as realistic sensing models, realistic energy consumption models, realistic connectivity models and sensor localization are covered

    A stochastic and dynamical view of pluripotency in mouse embryonic stem cells

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    Pluripotent embryonic stem cells are of paramount importance for biomedical research thanks to their innate ability for self-renewal and differentiation into all major cell lines. The fateful decision to exit or remain in the pluripotent state is regulated by complex genetic regulatory network. Latest advances in transcriptomics have made it possible to infer basic topologies of pluripotency governing networks. The inferred network topologies, however, only encode boolean information while remaining silent about the roles of dynamics and molecular noise in gene expression. These features are widely considered essential for functional decision making. Herein we developed a framework for extending the boolean level networks into models accounting for individual genetic switches and promoter architecture which allows mechanistic interrogation of the roles of molecular noise, external signaling, and network topology. We demonstrate the pluripotent state of the network to be a broad attractor which is robust to variations of gene expression. Dynamics of exiting the pluripotent state, on the other hand, is significantly influenced by the molecular noise originating from genetic switching events which makes cells more responsive to extracellular signals. Lastly we show that steady state probability landscape can be significantly remodeled by global gene switching rates alone which can be taken as a proxy for how global epigenetic modifications exert control over stability of pluripotent states.Comment: 11 pages, 7 figure

    Spin-Based Neuron Model with Domain Wall Magnets as Synapse

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    We present artificial neural network design using spin devices that achieves ultra low voltage operation, low power consumption, high speed, and high integration density. We employ spin torque switched nano-magnets for modelling neuron and domain wall magnets for compact, programmable synapses. The spin based neuron-synapse units operate locally at ultra low supply voltage of 30mV resulting in low computation power. CMOS based inter-neuron communication is employed to realize network-level functionality. We corroborate circuit operation with physics based models developed for the spin devices. Simulation results for character recognition as a benchmark application shows 95% lower power consumption as compared to 45nm CMOS design
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