Optic nerve head segmentation

Reliable and efficient optic disk localization and segmentation are important tasks in automated retinal screening. General-purpose edge detection algorithms often fail to segment the optic disk due to fuzzy boundaries, inconsistent image contrast or missing edge features. This paper presents an algorithm for the localization and segmentation of the optic nerve head boundary in low-resolution images (about 20 /spl mu//pixel). Optic disk localization is achieved using specialized template matching, and segmentation by a deformable contour model. The latter uses a global elliptical model and a local deformable model with variable edge-strength dependent stiffness. The algorithm is evaluated against a randomly selected database of 100 images from a diabetic screening programme. Ten images were classified as unusable; the others were of variable quality. The localization algorithm succeeded on all bar one usable image; the contour estimation algorithm was qualitatively assessed by an ophthalmologist as having Excellent-Fair performance in 83% of cases, and performs well even on blurred image

Application of the Fisher-Rao metric to ellipse detection

The parameter space for the ellipses in a two dimensional image is a five dimensional manifold, where each point of the manifold corresponds to an ellipse in the image. The parameter space becomes a Riemannian manifold under a Fisher-Rao metric, which is derived from a Gaussian model for the blurring of ellipses in the image. Two points in the parameter space are close together under the Fisher-Rao metric if the corresponding ellipses are close together in the image. The Fisher-Rao metric is accurately approximated by a simpler metric under the assumption that the blurring is small compared with the sizes of the ellipses under consideration. It is shown that the parameter space for the ellipses in the image has a finite volume under the approximation to the Fisher-Rao metric. As a consequence the parameter space can be replaced, for the purpose of ellipse detection, by a finite set of points sampled from it. An efficient algorithm for sampling the parameter space is described. The algorithm uses the fact that the approximating metric is flat, and therefore locally Euclidean, on each three dimensional family of ellipses with a fixed orientation and a fixed eccentricity. Once the sample points have been obtained, ellipses are detected in a given image by checking each sample point in turn to see if the corresponding ellipse is supported by the nearby image pixel values. The resulting algorithm for ellipse detection is implemented. A multiresolution version of the algorithm is also implemented. The experimental results suggest that ellipses can be reliably detected in a given low resolution image and that the number of false detections can be reduced using the multiresolution algorithm

Tangent-ball techniques for shape processing

Shape processing defines a set of theoretical and algorithmic tools for creating, measuring and modifying digital representations of shapes.  Such tools are of paramount importance to many disciplines of computer graphics, including modeling, animation, visualization, and image processing.  Many applications of shape processing can be found in the entertainment and medical industries. In an attempt to improve upon many previous shape processing techniques, the present thesis explores the theoretical and algorithmic aspects of a difference measure, which involves fitting a ball (disk in 2D and sphere in 3D) so that it has at least one tangential contact with each shape and the ball interior is disjoint from both shapes. We propose a set of ball-based operators and discuss their properties, implementations, and applications.  We divide the group of ball-based operations into unary and binary as follows: Unary operators include: * Identifying details (sharp, salient features, constrictions) * Smoothing shapes by removing such details, replacing them by fillets and roundings * Segmentation (recognition, abstract modelization via centerline and radius variation) of tubular structures Binary operators include: * Measuring the local discrepancy between two shapes * Computing the average of two shapes * Computing point-to-point correspondence between two shapes * Computing circular trajectories between corresponding points that meet both shapes at right angles * Using these trajectories to support smooth morphing (inbetweening) * Using a curve morph to construct surfaces that interpolate between contours on consecutive slices The technical contributions of this thesis focus on the implementation of these tangent-ball operators and their usefulness in applications of shape processing. We show specific applications in the areas of animation and computer-aided medical diagnosis.  These algorithms are simple to implement, mathematically elegant, and fast to execute.Ph.D.Committee Chair: Jarek Rossignac; Committee Member: Greg Slabaugh; Committee Member: Greg Turk; Committee Member: Karen Liu; Committee Member: Maryann Simmon

Dagstuhl Reports : Volume 1, Issue 2, February 2011

Online Privacy: Towards Informational Self-Determination on the Internet (Dagstuhl Perspectives Workshop 11061) : Simone Fischer-Hübner, Chris Hoofnagle, Kai Rannenberg, Michael Waidner, Ioannis Krontiris and Michael Marhöfer Self-Repairing Programs (Dagstuhl Seminar 11062) : Mauro Pezzé, Martin C. Rinard, Westley Weimer and Andreas Zeller Theory and Applications of Graph Searching Problems (Dagstuhl Seminar 11071) : Fedor V. Fomin, Pierre Fraigniaud, Stephan Kreutzer and Dimitrios M. Thilikos Combinatorial and Algorithmic Aspects of Sequence Processing (Dagstuhl Seminar 11081) : Maxime Crochemore, Lila Kari, Mehryar Mohri and Dirk Nowotka Packing and Scheduling Algorithms for Information and Communication Services (Dagstuhl Seminar 11091) Klaus Jansen, Claire Mathieu, Hadas Shachnai and Neal E. Youn

Computer vision

The field of computer vision is surveyed and assessed, key research issues are identified, and possibilities for a future vision system are discussed. The problems of descriptions of two and three dimensional worlds are discussed. The representation of such features as texture, edges, curves, and corners are detailed. Recognition methods are described in which cross correlation coefficients are maximized or numerical values for a set of features are measured. Object tracking is discussed in terms of the robust matching algorithms that must be devised. Stereo vision, camera control and calibration, and the hardware and systems architecture are discussed

Active skeleton for bacteria modeling

The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the molecular components of interest are protein aggregates accumulated near bacteria boundaries. This particular location makes very ambiguous the correspondence between aggregates and cells, since computing accurately bacteria boundaries in phase-contrast time-lapse imaging is a challenging task. This paper proposes an active skeleton formulation for bacteria modeling which provides several advantages: an easy computation of shape properties (perimeter, length, thickness, orientation), an improved boundary accuracy in noisy images, and a natural bacteria-centered coordinate system that permits the intrinsic location of molecular components inside the cell. Starting from an initial skeleton estimate, the medial axis of the bacterium is obtained by minimizing an energy function which incorporates bacteria shape constraints. Experimental results on biological images and comparative evaluation of the performances validate the proposed approach for modeling cigar-shaped bacteria like Escherichia coli. The Image-J plugin of the proposed method can be found online at http://fluobactracker.inrialpes.fr.Comment: Published in Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualizationto appear i

A higher-order active contour model of a `gas of circles' and its application to tree crown extraction

Many image processing problems involve identifying the region in the image domain occupied by a given entity in the scene. Automatic solution of these problems requires models that incorporate significant prior knowledge about the shape of the region. Many methods for including such knowledge run into difficulties when the topology of the region is unknown a priori, for example when the entity is composed of an unknown number of similar objects. Higher-order active contours (HOACs) represent one method for the modelling of non-trivial prior knowledge about shape without necessarily constraining region topology, via the inclusion of non-local interactions between region boundary points in the energy defining the model. The case of an unknown number of circular objects arises in a number of domains, e.g. medical, biological, nanotechnological, and remote sensing imagery. Regions composed of an a priori unknown number of circles may be referred to as a `gas of circles'. In this report, we present a HOAC model of a `gas of circles'. In order to guarantee stable circles, we conduct a stability analysis via a functional Taylor expansion of the HOAC energy around a circular shape. This analysis fixes one of the model parameters in terms of the others and constrains the rest. In conjunction with a suitable likelihood energy, we apply the model to the extraction of tree crowns from aerial imagery, and show that the new model outperforms other techniques