IST Austria Thesis

Hybrid automata combine finite automata and dynamical systems, and model the interaction of digital with physical systems. Formal analysis that can guarantee the safety of all behaviors or rigorously witness failures, while unsolvable in general, has been tackled algorithmically using, e.g., abstraction, bounded model-checking, assisted theorem proving. Nevertheless, very few methods have addressed the time-unbounded reachability analysis of hybrid automata and, for current sound and automatic tools, scalability remains critical. We develop methods for the polyhedral abstraction of hybrid automata, which construct coarse overapproximations and tightens them incrementally, in a CEGAR fashion. We use template polyhedra, i.e., polyhedra whose facets are normal to a given set of directions. While, previously, directions were given by the user, we introduce (1) the first method for computing template directions from spurious counterexamples, so as to generalize and eliminate them. The method applies naturally to convex hybrid automata, i.e., hybrid automata with (possibly non-linear) convex constraints on derivatives only, while for linear ODE requires further abstraction. Specifically, we introduce (2) the conic abstractions, which, partitioning the state space into appropriate (possibly non-uniform) cones, divide curvy trajectories into relatively straight sections, suitable for polyhedral abstractions. Finally, we introduce (3) space-time interpolation, which, combining interval arithmetic and template refinement, computes appropriate (possibly non-uniform) time partitioning and template directions along spurious trajectories, so as to eliminate them. We obtain sound and automatic methods for the reachability analysis over dense and unbounded time of convex hybrid automata and hybrid automata with linear ODE. We build prototype tools and compare—favorably—our methods against the respective state-of-the-art tools, on several benchmarks

Approximated Symbolic Computations over Hybrid Automata

Hybrid automata are a natural framework for modeling and analyzing systems which exhibit a mixed discrete continuous behaviour. However, the standard operational semantics defined over such models implicitly assume perfect knowledge of the real systems and infinite precision measurements. Such assumptions are not only unrealistic, but often lead to the construction of misleading models. For these reasons we believe that it is necessary to introduce more flexible semantics able to manage with noise, partial information, and finite precision instruments. In particular, in this paper we integrate in a single framework based on approximated semantics different over and under-approximation techniques for hybrid automata. Our framework allows to both compare, mix, and generalize such techniques obtaining different approximated reachability algorithms.Comment: In Proceedings HAS 2013, arXiv:1308.490

Weak Singular Hybrid Automata

The framework of Hybrid automata, introduced by Alur, Courcourbetis, Henzinger, and Ho, provides a formal modeling and analysis environment to analyze the interaction between the discrete and the continuous parts of cyber-physical systems. Hybrid automata can be considered as generalizations of finite state automata augmented with a finite set of real-valued variables whose dynamics in each state is governed by a system of ordinary differential equations. Moreover, the discrete transitions of hybrid automata are guarded by constraints over the values of these real-valued variables, and enable discontinuous jumps in the evolution of these variables. Singular hybrid automata are a subclass of hybrid automata where dynamics is specified by state-dependent constant vectors. Henzinger, Kopke, Puri, and Varaiya showed that for even very restricted subclasses of singular hybrid automata, the fundamental verification questions, like reachability and schedulability, are undecidable. In this paper we present \emph{weak singular hybrid automata} (WSHA), a previously unexplored subclass of singular hybrid automata, and show the decidability (and the exact complexity) of various verification questions for this class including reachability (NP-Complete) and LTL model-checking (PSPACE-Complete). We further show that extending WSHA with a single unrestricted clock or extending WSHA with unrestricted variable updates lead to undecidability of reachability problem

Algorithmic Verification of Continuous and Hybrid Systems

We provide a tutorial introduction to reachability computation, a class of computational techniques that exports verification technology toward continuous and hybrid systems. For open under-determined systems, this technique can sometimes replace an infinite number of simulations.Comment: In Proceedings INFINITY 2013, arXiv:1402.661

Towards Personalized Prostate Cancer Therapy Using Delta-Reachability Analysis

Recent clinical studies suggest that the efficacy of hormone therapy for prostate cancer depends on the characteristics of individual patients. In this paper, we develop a computational framework for identifying patient-specific androgen ablation therapy schedules for postponing the potential cancer relapse. We model the population dynamics of heterogeneous prostate cancer cells in response to androgen suppression as a nonlinear hybrid automaton. We estimate personalized kinetic parameters to characterize patients and employ $\delta$-reachability analysis to predict patient-specific therapeutic strategies. The results show that our methods are promising and may lead to a prognostic tool for personalized cancer therapy.Comment: HSCC 201