London SynEx Demonstrator Site: Impact Assessment Report

The key ingredients of the SynEx-UCL software components are: 1. A comprehensive and federated electronic healthcare record that can be used to reference or to store all of the necessary healthcare information acquired from a diverse range of clinical databases and patient-held devices. 2. A directory service component to provide a core persons demographic database to search for and authenticate staff users of the system and to anchor patient identification and connection to their federated healthcare record. 3. A clinical record schema management tool (Object Dictionary Client) that enables clinicians or engineers to define and export the data sets mapping to individual feeder systems. 4. An expansible set of clinical management algorithms that provide prompts to the patient or clinician to assist in the management of patient care. CHIME has built up over a decade of experience within Europe on the requirements and information models that are needed to underpin comprehensive multiprofessional electronic healthcare records. The resulting architecture models have influenced new European standards in this area, and CHIME has designed and built prototype EHCR components based on these models. The demonstrator systems described here utilise a directory service and object-oriented engineering approach, and support the secure, mobile and distributed access to federated healthcare records via web-based services. The design and implementation of these software components has been founded on a thorough analysis of the clinical, technical and ethico-legal requirements for comprehensive EHCR systems, published through previous project deliverables and in future planned papers. The clinical demonstrator site described in this report has provided the solid basis from which to establish "proof of concept" verification of the design approach, and a valuable opportunity to install, test and evaluate the results of the component engineering undertaken during the EC funded project. Inevitably, a number of practical implementation and deployment obstacles have been overcome through this journey, each of those having contributed to the time taken to deliver the components but also to the richness of the end products. UCL is fortunate that the Whittington Hospital, and the department of cardiovascular medicine in particular, is committed to a long-term vision built around this work. That vision, outlined within this report, is shared by the Camden and Islington Health Authority and by many other purchaser and provider organisations in the area, and by a number of industrial parties. They are collectively determined to support the Demonstrator Site as an ongoing project well beyond the life of the EC SynEx Project. This report, although a final report as far as the EC project is concerned, is really a description of the first phase in establishing a centre of healthcare excellence. New EC Fifth Framework project funding has already been approved to enable new and innovative technology solutions to be added to the work already established in north London

Consolidated List of Requirements

This document is a consolidated catalogue of requirements for the Electronic Health Care Record (EHCR) and Electronic Health Care Record Architecture (EHCRA), gleaned largely from work done in the EU Framework III and IV programmes and CEN, but also including input from other sources including world-wide standardisation initiatives. The document brings together the relevant work done into a classified inventory of requirements to inform the on-going standardisation process as well as act as a guide to future implementation of EHCRA-based systems. It is meant as a contribution both to understanding of the standard and to the work that is being considered to improve the standard. Major features include the classification into issues affecting the Health Care Record, the EHCR, EHCR processing, EHCR interchange and the sharing of health care information and EHCR systems. The principal information sources are described briefly. It is offered as documentation that is complementary to the four documents of the ENV 13606 Parts I-IV produced by CEN Pts 26,27,28,29. The requirements identified and classified in this deliverable are referenced in other deliverables

Noninvasive methods for children\u27s cholesterol level determination

Today, there is a controversy about the role of cholesterol in infants and the measurement and management of blood cholesterol in children. Several scientific evidences are supporting relationship between elevated blood cholesterol in children and high cholesterol in adults and development of adult arteriosclerotic diseases such as cardiovascular and cerebrovascular disease. Therefore controlling the level of blood cholesterol in children is very important for the health of the whole population. Non-invasive methods are much more convenient for the children because of their anxieties about blood examinations. In this paper we will present a new try to find non-invasive methods for determining the level of blood cholesterol in children with the use of intelligent system

Surface EMG decomposition using a novel approach for blind source separation

We introduce a new method to perform a blind deconvolution of the surface electromyogram (EMG) signals generated by isometric muscle contractions. The method extracts the information from the raw EMG signals detected only on the skin surface, enabling longtime noninvasive monitoring of the electromuscular properties. Its preliminary results show that surface EMG signals can be used to determine the number of active motor units, the motor unit firing rate and the shape of the average action potential in each motor unit

Oblikovanje programskih jezika za događajima poticanu kompoziciju usluga

To adapt to rapidly changing market conditions and increase the return of investment, today’s IT solutions usually combine service-oriented architecture (SOA) and event-driven architecture (EDA) that support reusability, flexibility, and responsiveness of business processes. Programming languages for development of event-driven service compositions face several main challenges. First, a language should be based on standard service composition languages to be compatible with SOA-enabling technologies. Second, a language should enable seamless integration of services into event-driven workflows. Third, to overcome a knowledge divide, language should enable seamless cooperation between application developers with different skills and knowledge. Since WS-BPEL is widely accepted as standard executable language in SOA, we extended WS-BPEL with support for event-driven workflow coordination. We designed event-handling mechanisms as special-purpose Coopetition services and augmented WS-BPEL with primitives for their invocation. Coopetition services augment SOA with fundamental EDA characteristics: decoupled interactions, many-to-many communication, publish/subscribe messaging, event triggering, and asynchronous operations. To make the application development familiar to wide community of developers, we designed an application-level end-user language on top of WS-BPEL whose primitives for invocation of regular Web services and Coopetition services resemble the constructs of typical scripting and coordination language.S ciljem prilagodbe promjenjivim tržišnim uvjetima i povećanja isplativosti ulaganja, današnji informacijski sustavi grade se spregom uslužno usmjerene i događajima poticane arhitekture koje omogućuju oblikovanje višestruko iskoristivih i prilagodljivih poslovnih procesa s mogućnošću odziva na pojavu događaja. Programski jezici za događajima poticanu kompoziciju usluga pokazuju nekoliko glavnih značajki. Prvo, jezik mora naslijediti svojstva standardnih jezika za kompoziciju usluga kako bi bio sukladan tehnologijama uslužno-usmjerene arhitekture. Drugo, jezik mora omogućiti prirodni način povezivanja usluga u događajima poticane poslovne procese. Treće, razvijateljima različitih znanja i vještina potrebno je osigurati mogućnost udruženog sudjelovanja u razvoju primjenskih programa. Budući da je WS-BPEL standardni jezik za kompoziciju usluga, izabran je kao osnovica za oblikovanje jezika za događajima poticanu kompoziciju usluga. Oblikovan je poseban skup usluga suradnje i natjecanja kojima je uslužno-usmjerena arhitektura proširena elementima događajima poticane arhitekture, kao što su međudjelovanje zasnovano na slaboj povezivosti, komunikacija u grupi, objava/pretplata, reakcija na pojavu događaja i asinkrone operacije. Jezik WS-BPEL proširen je programskim primitivama za pozivanje tih usluga. Kako bi se razvoj primjenskih programa približio širokoj zajednici graditelja programske potpore, povrh jezika WS-BPEL oblikovan je primjenski jezik za krajnjeg korisnika čije primitive za pozivanje primjenskih usluga te usluga suradnje i natjecanja nalikuju naredbama skriptnih i koordinacijskih jezika

An Architecture for Provenance Systems

This document covers the logical and process architectures of provenance systems. The logical architecture identifies key roles and their interactions, whereas the process architecture discusses distribution and security. A fundamental aspect of our presentation is its technology-independent nature, which makes it reusable: the principles that are exposed in this document may be applied to different technologies

On the Use of XML in Medical Imaging Web-Based Applications

The rapid growth of digital technology in medical fields over recent years has increased the need for applications able to manage patient medical records, imaging data, and chart information. Web-based applications are implemented with the purpose to link digital databases, storage and transmission protocols, management of large volumes of data and security concepts, allowing the possibility to read, analyze, and even diagnose remotely from the medical center where the information was acquired. The objective of this paper is to analyze the use of the Extensible Markup Language (XML) language in web-based applications that aid in diagnosis or treatment of patients, considering how this protocol allows indexing and exchanging the huge amount of information associated with each medical case. The purpose of this paper is to point out the main advantages and drawbacks of the XML technology in order to provide key ideas for future web-based applicationsPeer ReviewedPostprint (author's final draft

Medical informatics : the generic interchange of comprehensive health data

The objective of this project was to study the area of generic transfer of comprehensive medical data.The work presented in this thesis had as its main premise the belief that generic transfer of comprehensive medical data will help towards the goal of better healthcare particularly in an environment of shared care. It studied the main methods of data transfer available at present, and as a result carried out an in depth review of one such method adopted by the National Health Service (NHS). Criticism of this method was made. These criticisms lead on to the development of an alternative method of generic data transfer based on an emerging European standard for the storage of medical data. This in turn led on to the consideration of data in legacy systems. Finally, an evaluation of the developed method was undertaken

Medical informatics : the generic interchange of comprehensive health data

The objective of this project was to study the area of generic transfer of comprehensive medical data.The work presented in this thesis had as its main premise the belief that generic transfer of comprehensive medical data will help towards the goal of better healthcare particularly in an environment of shared care. It studied the main methods of data transfer available at present, and as a result carried out an in depth review of one such method adopted by the National Health Service (NHS). Criticism of this method was made. These criticisms lead on to the development of an alternative method of generic data transfer based on an emerging European standard for the storage of medical data. This in turn led on to the consideration of data in legacy systems. Finally, an evaluation of the developed method was undertaken