5,246 research outputs found
Multiobjective optimization to a TB-HIV/AIDS coinfection optimal control problem
We consider a recent coinfection model for Tuberculosis (TB), Human
Immunodeficiency Virus (HIV) infection and Acquired Immunodeficiency Syndrome
(AIDS) proposed in [Discrete Contin. Dyn. Syst. 35 (2015), no. 9, 4639--4663].
We introduce and analyze a multiobjective formulation of an optimal control
problem, where the two conflicting objectives are: minimization of the number
of HIV infected individuals with AIDS clinical symptoms and coinfected with
AIDS and active TB; and costs related to prevention and treatment of HIV and/or
TB measures. The proposed approach eliminates some limitations of previous
works. The results of the numerical study provide comprehensive insights about
the optimal treatment policies and the population dynamics resulting from their
implementation. Some nonintuitive conclusions are drawn. Overall, the
simulation results demonstrate the usefulness and validity of the proposed
approach.Comment: This is a preprint of a paper whose final and definite form is with
'Computational and Applied Mathematics', ISSN 0101-8205 (print), ISSN
1807-0302 (electronic). Submitted 04-Feb-2016; revised 11-June-2016 and
02-Sept-2016; accepted for publication 15-March-201
An efficient method for multiobjective optimal control and optimal control subject to integral constraints
We introduce a new and efficient numerical method for multicriterion optimal
control and single criterion optimal control under integral constraints. The
approach is based on extending the state space to include information on a
"budget" remaining to satisfy each constraint; the augmented
Hamilton-Jacobi-Bellman PDE is then solved numerically. The efficiency of our
approach hinges on the causality in that PDE, i.e., the monotonicity of
characteristic curves in one of the newly added dimensions. A semi-Lagrangian
"marching" method is used to approximate the discontinuous viscosity solution
efficiently. We compare this to a recently introduced "weighted sum" based
algorithm for the same problem. We illustrate our method using examples from
flight path planning and robotic navigation in the presence of friendly and
adversarial observers.Comment: The final version accepted by J. Comp. Math. : 41 pages, 14 figures.
Since the previous version: typos fixed, formatting improved, one mistake in
bibliography correcte
A multiobjective optimization framework for multicontaminant industrial water network design.
The optimal design of multicontaminant industrial water networks according to several objectives is carried out in this paper. The general formulation of the water allocation problem (WAP) is given as a set of nonlinear equations with binary variables representing the presence of interconnections in the network. For optimization purposes, three antagonist objectives are considered: F1, the freshwater flow-rate at the network entrance, F2, the water flow-rate at inlet of regeneration units, and F3, the number of interconnections in the network. The multiobjective problem is solved via a lexicographic strategy, where a mixed-integer nonlinear programming (MINLP) procedure is used at each step. The approach is illustrated by a numerical example taken from the literature involving five processes, one regeneration unit and three contaminants. The set of potential network solutions is provided in the form of a Pareto front. Finally, the strategy for choosing the best network solution among those given by Pareto fronts is presented. This Multiple Criteria Decision Making (MCDM) problem is tackled by means of two approaches: a classical TOPSIS analysis is first implemented and then an innovative strategy based on the global equivalent cost (GEC) in freshwater that turns out to be more efficient for choosing a good network according to a practical point of view
Singular Continuation: Generating Piece-wise Linear Approximations to Pareto Sets via Global Analysis
We propose a strategy for approximating Pareto optimal sets based on the
global analysis framework proposed by Smale (Dynamical systems, New York, 1973,
pp. 531-544). The method highlights and exploits the underlying manifold
structure of the Pareto sets, approximating Pareto optima by means of
simplicial complexes. The method distinguishes the hierarchy between singular
set, Pareto critical set and stable Pareto critical set, and can handle the
problem of superposition of local Pareto fronts, occurring in the general
nonconvex case. Furthermore, a quadratic convergence result in a suitable
set-wise sense is proven and tested in a number of numerical examples.Comment: 29 pages, 12 figure
Mutual benefits of two multicriteria analysis methodologies: A case study for batch plant design
This paper presents a MultiObjective Genetic Algorithm (MOGA) optimization framework for batch plant design. For this purpose, two approaches are implemented and compared with respect to three criteria, i.e., investment cost, equipment number and a flexibility indicator based on work in process (the so-called WIP) computed by use of a discrete-event simulation model. The first approach involves a genetic algorithm in order to generate acceptable solutions, from which the best ones are chosen by using a Pareto Sort algorithm. The second approach combines the previous Genetic Algorithm with a multicriteria analysis methodology, i.e., the Electre method in order to find the best solutions. The performances of the two procedures are studied for a large-size problem and a comparison between the procedures is then made
A Descent Method for Equality and Inequality Constrained Multiobjective Optimization Problems
In this article we propose a descent method for equality and inequality
constrained multiobjective optimization problems (MOPs) which generalizes the
steepest descent method for unconstrained MOPs by Fliege and Svaiter to
constrained problems by using two active set strategies. Under some regularity
assumptions on the problem, we show that accumulation points of our descent
method satisfy a necessary condition for local Pareto optimality. Finally, we
show the typical behavior of our method in a numerical example
Optimal Control and Sensitivity Analysis of a Fractional Order TB Model
A Caputo fractional-order mathematical model for the transmission dynamics of
tuberculosis (TB) was recently proposed in [Math. Model. Nat. Phenom. 13
(2018), no. 1, Art. 9]. Here, a sensitivity analysis of that model is done,
showing the importance of accuracy of parameter values. A fractional optimal
control (FOC) problem is then formulated and solved, with the rate of treatment
as the control variable. Finally, a cost-effectiveness analysis is performed to
assess the cost and the effectiveness of the control measures during the
intervention, showing in which conditions FOC is useful with respect to
classical (integer-order) optimal control.Comment: This is a preprint of a paper whose final and definite form is with
'Statistics Opt. Inform. Comput.', Vol. 7, No 2 (2019). See
[http://www.IAPress.org]. Submitted 09/Sept/2018; Revised 10/Dec/2018;
Accepted 11/Dec/2018. arXiv admin note: text overlap with arXiv:1801.09634,
arXiv:1810.0690
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