8,067 research outputs found
Numerical coupling of fluid and structure in cardiac flow and devices
Numerical simulations are a powerful tool in investigation of flow and structure
dynamics in biological systems and in the design of biomedical devices. Time-dependent
fluid-structure interaction (FSI) problems in biological systems are often characterized by
a periodic nature and relatively low Reynolds number. In order to solve the dynamics of
the fluid and structure of coupled systems, different approaches may be used. Several
parameters such as geometrical complexity, degree of displacement, convergence to
steady periodicity, and the system stability may determine the coupling method. In the
talk, four numerical studies of biological and implanted systems will be presented, each
with a different FSI approach. The first study is of flow through mechanical heart valves,
using finite-volume (FV) fluid solver coupled with an external structural solver using a
weak coupling scheme for large displacements. The second study is of flow inside a
pulsatile ventricular assist device with FV fluid solver coupled with finite-element (FE)
structure solver using a strong staggered coupling assuming small displacements. The
third study is of flow through vulnerable plaque in the coronary arteries, with FE solvers
for both the fluid and structure domains, using a fully-coupled iterative scheme assuming
small displacements. The fourth simulation is of an impedance pump using a direct FE
coupling method for large displacements. In addition to the methodology, the applicative
design and hemodynamic aspects of the cases will be discussed, including washout
properties and risk for thrombosis. The results obtained from the studies will be
compared to experimental analyses
The LifeV library: engineering mathematics beyond the proof of concept
LifeV is a library for the finite element (FE) solution of partial
differential equations in one, two, and three dimensions. It is written in C++
and designed to run on diverse parallel architectures, including cloud and high
performance computing facilities. In spite of its academic research nature,
meaning a library for the development and testing of new methods, one
distinguishing feature of LifeV is its use on real world problems and it is
intended to provide a tool for many engineering applications. It has been
actually used in computational hemodynamics, including cardiac mechanics and
fluid-structure interaction problems, in porous media, ice sheets dynamics for
both forward and inverse problems. In this paper we give a short overview of
the features of LifeV and its coding paradigms on simple problems. The main
focus is on the parallel environment which is mainly driven by domain
decomposition methods and based on external libraries such as MPI, the Trilinos
project, HDF5 and ParMetis.
Dedicated to the memory of Fausto Saleri.Comment: Review of the LifeV Finite Element librar
Fluid-structure interaction simulation of prosthetic aortic valves : comparison between immersed boundary and arbitrary Lagrangian-Eulerian techniques for the mesh representation
In recent years the role of FSI (fluid-structure interaction) simulations in the analysis of the fluid-mechanics of heart valves is becoming more and more important, being able to capture the interaction between the blood and both the surrounding biological tissues and the valve itself. When setting up an FSI simulation, several choices have to be made to select the most suitable approach for the case of interest: in particular, to simulate flexible leaflet cardiac valves, the type of discretization of the fluid domain is crucial, which can be described with an ALE (Arbitrary Lagrangian-Eulerian) or an Eulerian formulation. The majority of the reported 3D heart valve FSI simulations are performed with the Eulerian formulation, allowing for large deformations of the domains without compromising the quality of the fluid grid. Nevertheless, it is known that the ALE-FSI approach guarantees more accurate results at the interface between the solid and the fluid. The goal of this paper is to describe the same aortic valve model in the two cases, comparing the performances of an ALE-based FSI solution and an Eulerian-based FSI approach. After a first simplified 2D case, the aortic geometry was considered in a full 3D set-up. The model was kept as similar as possible in the two settings, to better compare the simulations' outcomes. Although for the 2D case the differences were unsubstantial, in our experience the performance of a full 3D ALE-FSI simulation was significantly limited by the technical problems and requirements inherent to the ALE formulation, mainly related to the mesh motion and deformation of the fluid domain. As a secondary outcome of this work, it is important to point out that the choice of the solver also influenced the reliability of the final results
A partition of unity approach to fluid mechanics and fluid-structure interaction
For problems involving large deformations of thin structures, simulating
fluid-structure interaction (FSI) remains challenging largely due to the need
to balance computational feasibility, efficiency, and solution accuracy.
Overlapping domain techniques have been introduced as a way to combine the
fluid-solid mesh conformity, seen in moving-mesh methods, without the need for
mesh smoothing or re-meshing, which is a core characteristic of fixed mesh
approaches. In this work, we introduce a novel overlapping domain method based
on a partition of unity approach. Unified function spaces are defined as a
weighted sum of fields given on two overlapping meshes. The method is shown to
achieve optimal convergence rates and to be stable for steady-state Stokes,
Navier-Stokes, and ALE Navier-Stokes problems. Finally, we present results for
FSI in the case of a 2D mock aortic valve simulation. These initial results
point to the potential applicability of the method to a wide range of FSI
applications, enabling boundary layer refinement and large deformations without
the need for re-meshing or user-defined stabilization.Comment: 34 pages, 15 figur
Immersed boundary-finite element model of fluid-structure interaction in the aortic root
It has long been recognized that aortic root elasticity helps to ensure
efficient aortic valve closure, but our understanding of the functional
importance of the elasticity and geometry of the aortic root continues to
evolve as increasingly detailed in vivo imaging data become available. Herein,
we describe fluid-structure interaction models of the aortic root, including
the aortic valve leaflets, the sinuses of Valsalva, the aortic annulus, and the
sinotubular junction, that employ a version of Peskin's immersed boundary (IB)
method with a finite element (FE) description of the structural elasticity. We
develop both an idealized model of the root with three-fold symmetry of the
aortic sinuses and valve leaflets, and a more realistic model that accounts for
the differences in the sizes of the left, right, and noncoronary sinuses and
corresponding valve cusps. As in earlier work, we use fiber-based models of the
valve leaflets, but this study extends earlier IB models of the aortic root by
employing incompressible hyperelastic models of the mechanics of the sinuses
and ascending aorta using a constitutive law fit to experimental data from
human aortic root tissue. In vivo pressure loading is accounted for by a
backwards displacement method that determines the unloaded configurations of
the root models. Our models yield realistic cardiac output at physiological
pressures, with low transvalvular pressure differences during forward flow,
minimal regurgitation during valve closure, and realistic pressure loads when
the valve is closed during diastole. Further, results from high-resolution
computations demonstrate that IB models of the aortic valve are able to produce
essentially grid-converged dynamics at practical grid spacings for the
high-Reynolds number flows of the aortic root
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