3D Medical Image Lossless Compressor Using Deep Learning Approaches

The ever-increasing importance of accelerated information processing, communica-tion, and storing are major requirements within the big-data era revolution. With the extensive rise in data availability, handy information acquisition, and growing data rate, a critical challenge emerges in efficient handling. Even with advanced technical hardware developments and multiple Graphics Processing Units (GPUs) availability, this demand is still highly promoted to utilise these technologies effectively. Health-care systems are one of the domains yielding explosive data growth. Especially when considering their modern scanners abilities, which annually produce higher-resolution and more densely sampled medical images, with increasing requirements for massive storage capacity. The bottleneck in data transmission and storage would essentially be handled with an effective compression method. Since medical information is critical and imposes an influential role in diagnosis accuracy, it is strongly encouraged to guarantee exact reconstruction with no loss in quality, which is the main objective of any lossless compression algorithm. Given the revolutionary impact of Deep Learning (DL) methods in solving many tasks while achieving the state of the art results, includ-ing data compression, this opens tremendous opportunities for contributions. While considerable efforts have been made to address lossy performance using learning-based approaches, less attention was paid to address lossless compression. This PhD thesis investigates and proposes novel learning-based approaches for compressing 3D medical images losslessly.Firstly, we formulate the lossless compression task as a supervised sequential prediction problem, whereby a model learns a projection function to predict a target voxel given sequence of samples from its spatially surrounding voxels. Using such 3D local sampling information efficiently exploits spatial similarities and redundancies in a volumetric medical context by utilising such a prediction paradigm. The proposed NN-based data predictor is trained to minimise the differences with the original data values while the residual errors are encoded using arithmetic coding to allow lossless reconstruction.Following this, we explore the effectiveness of Recurrent Neural Networks (RNNs) as a 3D predictor for learning the mapping function from the spatial medical domain (16 bit-depths). We analyse Long Short-Term Memory (LSTM) models’ generalisabil-ity and robustness in capturing the 3D spatial dependencies of a voxel’s neighbourhood while utilising samples taken from various scanning settings. We evaluate our proposed MedZip models in compressing unseen Computerized Tomography (CT) and Magnetic Resonance Imaging (MRI) modalities losslessly, compared to other state-of-the-art lossless compression standards.This work investigates input configurations and sampling schemes for a many-to-one sequence prediction model, specifically for compressing 3D medical images (16 bit-depths) losslessly. The main objective is to determine the optimal practice for enabling the proposed LSTM model to achieve a high compression ratio and fast encoding-decoding performance. A solution for a non-deterministic environments problem was also proposed, allowing models to run in parallel form without much compression performance drop. Compared to well-known lossless codecs, experimental evaluations were carried out on datasets acquired by different hospitals, representing different body segments, and have distinct scanning modalities (i.e. CT and MRI).To conclude, we present a novel data-driven sampling scheme utilising weighted gradient scores for training LSTM prediction-based models. The objective is to determine whether some training samples are significantly more informative than others, specifically in medical domains where samples are available on a scale of billions. The effectiveness of models trained on the presented importance sampling scheme was evaluated compared to alternative strategies such as uniform, Gaussian, and sliced-based sampling

Lossless Compression of Medical Image Sequences Using a Resolution Independent Predictor and Block Adaptive Encoding

The proposed block-based lossless coding technique presented in this paper targets at compression of volumetric medical images of 8-bit and 16-bit depth. The novelty of the proposed technique lies in its ability of threshold selection for prediction and optimal block size for encoding. A resolution independent gradient edge detector is used along with the block adaptive arithmetic encoding algorithm with extensive experimental tests to find a universal threshold value and optimal block size independent of image resolution and modality. Performance of the proposed technique is demonstrated and compared with benchmark lossless compression algorithms. BPP values obtained from the proposed algorithm show that it is capable of effective reduction of inter-pixel and coding redundancy. In terms of coding efficiency, the proposed technique for volumetric medical images outperforms CALIC and JPEG-LS by 0.70 % and 4.62 %, respectively

MICROANGIOGRAM VIDEO COMPRESSION USING ADAPTIVE PREDICTION

Coronary angiography is an X-ray examination of the heart\u27s arteries. This is an essential technique for diagnosis of heart damages. Image sequences from digital angiography contain areas of high diagnostic interest. Loss of information due to compression for regions of interest (ROI) in angiograms is not tolerable. Since Commercially available technology such as JPEG and MPEG do not satisfy medical requirements due to their severe blockartifacts. In this paper, a new compression algorithm that achieves high compression ratio and excellent reconstruction quality for video rate or sub-video rate angiograms is developed. The proposed algorithm exploits temporal spatial and spectral redundancies in backward adaptive fashion with Extremely low side information. An experimental result shows that the proposed scheme provides significant improvements in compression efficiencies

A hybrid predictive technique for lossless image compression

Compression of images is of great interest in applications where efficiency with respect to data storage or transmission bandwidth is sought.The rapid growth of social media and digital networks have given rise to huge amount of image data being accessed and exchanged daily. However, the larger the image size, the longer it takes to transmit and archive. In other words, high quality images require huge amount of transmission bandwidth and storage space. Suitable image compression can help in reducing the image size and improving transmission speed. Lossless image compression is especially crucial in fields such as remote sensing healthcare network, security and military applications as the quality of images needs to be maintained to avoid any errors during analysis or diagnosis. In this paper, a hybrid prediction lossless image compression algorithm is proposed to address these issues. The algorithm is achieved by combining predictive Differential Pulse Code Modulation (DPCM) and Integer Wavelet Transform (IWT). Entropy and compression ratio calculation are used to analyze the performance of the designed coding. The analysis shows that the best hybrid predictive algorithm is the sequence of DPCM-IWT-Huffman which has bits sizes reduced by 36%, 48%, 34% and 13% for tested images of Lena, Cameraman, Pepper and Baboon, respectively

High capacity data embedding schemes for digital media

High capacity image data hiding methods and robust high capacity digital audio watermarking algorithms are studied in this thesis. The main results of this work are the development of novel algorithms with state-of-the-art performance, high capacity and transparency for image data hiding and robustness, high capacity and low distortion for audio watermarking.En esta tesis se estudian y proponen diversos métodos de data hiding de imágenes y watermarking de audio de alta capacidad. Los principales resultados de este trabajo consisten en la publicación de varios algoritmos novedosos con rendimiento a la altura de los mejores métodos del estado del arte, alta capacidad y transparencia, en el caso de data hiding de imágenes, y robustez, alta capacidad y baja distorsión para el watermarking de audio.En aquesta tesi s'estudien i es proposen diversos mètodes de data hiding d'imatges i watermarking d'àudio d'alta capacitat. Els resultats principals d'aquest treball consisteixen en la publicació de diversos algorismes nous amb rendiment a l'alçada dels millors mètodes de l'estat de l'art, alta capacitat i transparència, en el cas de data hiding d'imatges, i robustesa, alta capacitat i baixa distorsió per al watermarking d'àudio.Societat de la informació i el coneixemen