Forecasting daily patient outflow from a ward having no real-time clinical data

OBJECTIVE: Our study investigates different models to forecast the total number of next-day discharges from an open ward having no real-time clinical data. METHODS: We compared 5 popular regression algorithms to model total next-day discharges: (1) autoregressive integrated moving average (ARIMA), (2) the autoregressive moving average with exogenous variables (ARMAX), (3) k-nearest neighbor regression, (4) random forest regression, and (5) support vector regression. Although the autoregressive integrated moving average model relied on past 3-month discharges, nearest neighbor forecasting used median of similar discharges in the past in estimating next-day discharge. In addition, the ARMAX model used the day of the week and number of patients currently in ward as exogenous variables. For the random forest and support vector regression models, we designed a predictor set of 20 patient features and 88 ward-level features. RESULTS: Our data consisted of 12,141 patient visits over 1826 days. Forecasting quality was measured using mean forecast error, mean absolute error, symmetric mean absolute percentage error, and root mean square error. When compared with a moving average prediction model, all 5 models demonstrated superior performance with the random forests achieving 22.7% improvement in mean absolute error, for all days in the year 2014. CONCLUSIONS: In the absence of clinical information, our study recommends using patient-level and ward-level data in predicting next-day discharges. Random forest and support vector regression models are able to use all available features from such data, resulting in superior performance over traditional autoregressive methods. An intelligent estimate of available beds in wards plays a crucial role in relieving access block in emergency departments

Developing an advanced collision risk model for autonomous vehicles

Aiming at improving road safety, car manufacturers and researchers are verging upon autonomous vehicles. In recent years, collision prediction methods of autonomous vehicles have begun incorporating contextual information such as information about the traffic environment and the relative motion of other traffic participants but still fail to anticipate traffic scenarios of high complexity. During the past two decades, the problem of real-time collision prediction has also been investigated by traffic engineers. In the traffic engineering approach, a collision occurrence can potentially be predicted in real-time based on available data on traffic dynamics such as the average speed and flow of vehicles on a road segment. This thesis attempts to integrate vehicle-level collision prediction approaches for autonomous vehicles with network-level collision prediction, as studied by traffic engineers. [Continues.

Spatio-temporal forecasting of network data

In the digital age, data are collected in unprecedented volumes on a plethora of networks. These data provide opportunities to develop our understanding of network processes by allowing data to drive method, revealing new and often unexpected insights. To date, there has been extensive research into the structure and function of complex networks, but there is scope for improvement in modelling the spatio-temporal evolution of network processes in order to forecast future conditions. This thesis focusses on forecasting using data collected on road networks. Road traffic congestion is a serious and persistent problem in most major cities around the world, and it is the task of researchers and traffic engineers to make use of voluminous traffic data to help alleviate congestion. Recently, spatio-temporal models have been applied to traffic data, showing improvements over time series methods. Although progress has been made, challenges remain. Firstly, most existing methods perform well under typical conditions, but less well under atypical conditions. Secondly, existing spatio-temporal models have been applied to traffic data with high spatial resolution, and there has been little research into how to incorporate spatial information on spatially sparse sensor networks, where the dependency relationships between locations are uncertain. Thirdly, traffic data is characterised by high missing rates, and existing methods are generally poorly equipped to deal with this in a real time setting. In this thesis, a local online kernel ridge regression model is developed that addresses these three issues, with application to forecasting of travel times collected by automatic number plate recognition on London’s road network. The model parameters can vary spatially and temporally, allowing it to better model the time varying characteristics of traffic data, and to deal with abnormal traffic situations. Methods are defined for linking the spatially sparse sensor network to the physical road network, providing an improved representation of the spatial relationship between sensor locations. The incorporation of the spatio-temporal neighbourhood enables the model to forecast effectively under missing data. The proposed model outperforms a range of benchmark models at forecasting under normal conditions, and under various missing data scenarios

Forecasting: theory and practice

Forecasting has always been at the forefront of decision making and planning. The uncertainty that surrounds the future is both exciting and challenging, with individuals and organisations seeking to minimise risks and maximise utilities. The large number of forecasting applications calls for a diverse set of forecasting methods to tackle real-life challenges. This article provides a non-systematic review of the theory and the practice of forecasting. We provide an overview of a wide range of theoretical, state-of-the-art models, methods, principles, and approaches to prepare, produce, organise, and evaluate forecasts. We then demonstrate how such theoretical concepts are applied in a variety of real-life contexts. We do not claim that this review is an exhaustive list of methods and applications. However, we wish that our encyclopedic presentation will offer a point of reference for the rich work that has been undertaken over the last decades, with some key insights for the future of forecasting theory and practice. Given its encyclopedic nature, the intended mode of reading is non-linear. We offer cross-references to allow the readers to navigate through the various topics. We complement the theoretical concepts and applications covered by large lists of free or open-source software implementations and publicly-available databases.info:eu-repo/semantics/publishedVersio

Forecasting: theory and practice

Forecasting has always been at the forefront of decision making and planning. The uncertainty that surrounds the future is both exciting and challenging, with individuals and organisations seeking to minimise risks and maximise utilities. The large number of forecasting applications calls for a diverse set of forecasting methods to tackle real-life challenges. This article provides a non-systematic review of the theory and the practice of forecasting. We provide an overview of a wide range of theoretical, state-of-the-art models, methods, principles, and approaches to prepare, produce, organise, and evaluate forecasts. We then demonstrate how such theoretical concepts are applied in a variety of real-life contexts. We do not claim that this review is an exhaustive list of methods and applications. However, we wish that our encyclopedic presentation will offer a point of reference for the rich work that has been undertaken over the last decades, with some key insights for the future of forecasting theory and practice. Given its encyclopedic nature, the intended mode of reading is non-linear. We offer cross-references to allow the readers to navigate through the various topics. We complement the theoretical concepts and applications covered by large lists of free or open-source software implementations and publicly-available databases

Statistical methodology for the analysis of road safety data

PhD ThesisPTV Grou

Molecular phylogeny of horseshoe crab using mitochondrial Cox1 gene as a benchmark sequence

An effort to assess the utility of 650 bp Cytochrome C oxidase subunit I (DNA barcode) gene in delineating the members horseshoe crabs (Family: xiphosura) with closely related sister taxa was made. A total of 33 sequences were extracted from National Center for Biotechnological Information (NCBI) which include horseshoe crabs, beetles, common crabs and scorpion sequences. Constructed phylogram showed beetles are closely related with horseshoe crabs than common crabs. Scorpion spp were distantly related to xiphosurans. Phylogram and observed genetic distance (GD) date were also revealed that Limulus polyphemus was closely related with Tachypleus tridentatus than with T.gigas. Carcinoscorpius rotundicauda was distantly related with L.polyphemus. The observed mean Genetic Distance (GD) value was higher in 3rd codon position in all the selected group of organisms. Among the horseshoe crabs high GC content was observed in L.polyphemus (38.32%) and lowest was observed in T.tridentatus (32.35%). We conclude that COI sequencing (barcoding) could be used in identifying and delineating evolutionary relatedness with closely related specie

Crab and cockle shells as heterogeneous catalysts in the production of biodiesel

In the present study, the waste crab and cockle shells were utilized as source of calcium oxide to transesterify palm olein into methyl esters (biodiesel). Characterization results revealed that the main component of the shells are calcium carbonate which transformed into calcium oxide upon activated above 700 °C for 2 h. Parametric studies have been investigated and optimal conditions were found to be catalyst amount, 5 wt.% and methanol/oil mass ratio, 0.5:1. The waste catalysts perform equally well as laboratory CaO, thus creating another low-cost catalyst source for producing biodiesel. Reusability results confirmed that the prepared catalyst is able to be reemployed up to five times. Statistical analysis has been performed using a Central Composite Design to evaluate the contribution and performance of the parameters on biodiesel purity