19,525 research outputs found
Using multiple classifiers for predicting the risk of endovascular aortic aneurysm repair re-intervention through hybrid feature selection.
Feature selection is essential in medical area; however, its process becomes complicated with the presence of censoring which is the unique character of survival analysis. Most survival feature selection methods are based on Cox's proportional hazard model, though machine learning classifiers are preferred. They are less employed in survival analysis due to censoring which prevents them from directly being used to survival data. Among the few work that employed machine learning classifiers, partial logistic artificial neural network with auto-relevance determination is a well-known method that deals with censoring and perform feature selection for survival data. However, it depends on data replication to handle censoring which leads to unbalanced and biased prediction results especially in highly censored data. Other methods cannot deal with high censoring. Therefore, in this article, a new hybrid feature selection method is proposed which presents a solution to high level censoring. It combines support vector machine, neural network, and K-nearest neighbor classifiers using simple majority voting and a new weighted majority voting method based on survival metric to construct a multiple classifier system. The new hybrid feature selection process uses multiple classifier system as a wrapper method and merges it with iterated feature ranking filter method to further reduce features. Two endovascular aortic repair datasets containing 91% censored patients collected from two centers were used to construct a multicenter study to evaluate the performance of the proposed approach. The results showed the proposed technique outperformed individual classifiers and variable selection methods based on Cox's model such as Akaike and Bayesian information criterions and least absolute shrinkage and selector operator in p values of the log-rank test, sensitivity, and concordance index. This indicates that the proposed classifier is more powerful in correctly predicting the risk of re-intervention enabling doctor in selecting patients' future follow-up plan
An Attention-based Collaboration Framework for Multi-View Network Representation Learning
Learning distributed node representations in networks has been attracting
increasing attention recently due to its effectiveness in a variety of
applications. Existing approaches usually study networks with a single type of
proximity between nodes, which defines a single view of a network. However, in
reality there usually exists multiple types of proximities between nodes,
yielding networks with multiple views. This paper studies learning node
representations for networks with multiple views, which aims to infer robust
node representations across different views. We propose a multi-view
representation learning approach, which promotes the collaboration of different
views and lets them vote for the robust representations. During the voting
process, an attention mechanism is introduced, which enables each node to focus
on the most informative views. Experimental results on real-world networks show
that the proposed approach outperforms existing state-of-the-art approaches for
network representation learning with a single view and other competitive
approaches with multiple views.Comment: CIKM 201
3D Convolutional Neural Networks for Tumor Segmentation using Long-range 2D Context
We present an efficient deep learning approach for the challenging task of
tumor segmentation in multisequence MR images. In recent years, Convolutional
Neural Networks (CNN) have achieved state-of-the-art performances in a large
variety of recognition tasks in medical imaging. Because of the considerable
computational cost of CNNs, large volumes such as MRI are typically processed
by subvolumes, for instance slices (axial, coronal, sagittal) or small 3D
patches. In this paper we introduce a CNN-based model which efficiently
combines the advantages of the short-range 3D context and the long-range 2D
context. To overcome the limitations of specific choices of neural network
architectures, we also propose to merge outputs of several cascaded 2D-3D
models by a voxelwise voting strategy. Furthermore, we propose a network
architecture in which the different MR sequences are processed by separate
subnetworks in order to be more robust to the problem of missing MR sequences.
Finally, a simple and efficient algorithm for training large CNN models is
introduced. We evaluate our method on the public benchmark of the BRATS 2017
challenge on the task of multiclass segmentation of malignant brain tumors. Our
method achieves good performances and produces accurate segmentations with
median Dice scores of 0.918 (whole tumor), 0.883 (tumor core) and 0.854
(enhancing core). Our approach can be naturally applied to various tasks
involving segmentation of lesions or organs.Comment: Submitted to the journal Computerized Medical Imaging and Graphic
An Incremental Construction of Deep Neuro Fuzzy System for Continual Learning of Non-stationary Data Streams
Existing FNNs are mostly developed under a shallow network configuration
having lower generalization power than those of deep structures. This paper
proposes a novel self-organizing deep FNN, namely DEVFNN. Fuzzy rules can be
automatically extracted from data streams or removed if they play limited role
during their lifespan. The structure of the network can be deepened on demand
by stacking additional layers using a drift detection method which not only
detects the covariate drift, variations of input space, but also accurately
identifies the real drift, dynamic changes of both feature space and target
space. DEVFNN is developed under the stacked generalization principle via the
feature augmentation concept where a recently developed algorithm, namely
gClass, drives the hidden layer. It is equipped by an automatic feature
selection method which controls activation and deactivation of input attributes
to induce varying subsets of input features. A deep network simplification
procedure is put forward using the concept of hidden layer merging to prevent
uncontrollable growth of dimensionality of input space due to the nature of
feature augmentation approach in building a deep network structure. DEVFNN
works in the sample-wise fashion and is compatible for data stream
applications. The efficacy of DEVFNN has been thoroughly evaluated using seven
datasets with non-stationary properties under the prequential test-then-train
protocol. It has been compared with four popular continual learning algorithms
and its shallow counterpart where DEVFNN demonstrates improvement of
classification accuracy. Moreover, it is also shown that the concept drift
detection method is an effective tool to control the depth of network structure
while the hidden layer merging scenario is capable of simplifying the network
complexity of a deep network with negligible compromise of generalization
performance.Comment: This paper has been published in IEEE Transactions on Fuzzy System
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