7,666 research outputs found
Multi-view Learning as a Nonparametric Nonlinear Inter-Battery Factor Analysis
Factor analysis aims to determine latent factors, or traits, which summarize
a given data set. Inter-battery factor analysis extends this notion to multiple
views of the data. In this paper we show how a nonlinear, nonparametric version
of these models can be recovered through the Gaussian process latent variable
model. This gives us a flexible formalism for multi-view learning where the
latent variables can be used both for exploratory purposes and for learning
representations that enable efficient inference for ambiguous estimation tasks.
Learning is performed in a Bayesian manner through the formulation of a
variational compression scheme which gives a rigorous lower bound on the log
likelihood. Our Bayesian framework provides strong regularization during
training, allowing the structure of the latent space to be determined
efficiently and automatically. We demonstrate this by producing the first (to
our knowledge) published results of learning from dozens of views, even when
data is scarce. We further show experimental results on several different types
of multi-view data sets and for different kinds of tasks, including exploratory
data analysis, generation, ambiguity modelling through latent priors and
classification.Comment: 49 pages including appendi
Machine Learning and Integrative Analysis of Biomedical Big Data.
Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues
Recent Progress in Image Deblurring
This paper comprehensively reviews the recent development of image
deblurring, including non-blind/blind, spatially invariant/variant deblurring
techniques. Indeed, these techniques share the same objective of inferring a
latent sharp image from one or several corresponding blurry images, while the
blind deblurring techniques are also required to derive an accurate blur
kernel. Considering the critical role of image restoration in modern imaging
systems to provide high-quality images under complex environments such as
motion, undesirable lighting conditions, and imperfect system components, image
deblurring has attracted growing attention in recent years. From the viewpoint
of how to handle the ill-posedness which is a crucial issue in deblurring
tasks, existing methods can be grouped into five categories: Bayesian inference
framework, variational methods, sparse representation-based methods,
homography-based modeling, and region-based methods. In spite of achieving a
certain level of development, image deblurring, especially the blind case, is
limited in its success by complex application conditions which make the blur
kernel hard to obtain and be spatially variant. We provide a holistic
understanding and deep insight into image deblurring in this review. An
analysis of the empirical evidence for representative methods, practical
issues, as well as a discussion of promising future directions are also
presented.Comment: 53 pages, 17 figure
Representation Learning: A Review and New Perspectives
The success of machine learning algorithms generally depends on data
representation, and we hypothesize that this is because different
representations can entangle and hide more or less the different explanatory
factors of variation behind the data. Although specific domain knowledge can be
used to help design representations, learning with generic priors can also be
used, and the quest for AI is motivating the design of more powerful
representation-learning algorithms implementing such priors. This paper reviews
recent work in the area of unsupervised feature learning and deep learning,
covering advances in probabilistic models, auto-encoders, manifold learning,
and deep networks. This motivates longer-term unanswered questions about the
appropriate objectives for learning good representations, for computing
representations (i.e., inference), and the geometrical connections between
representation learning, density estimation and manifold learning
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