15,229 research outputs found
A stochastic large deformation model for computational anatomy
In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for incorporating random variations into the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework. By accounting for randomness in a particular setup which is crafted to fit the geometrical properties of LDDMM, we formulate the template estimation problem for landmarks with noise and give two methods for efficiently estimating the parameters of the noise fields from a prescribed data set. One method directly approximates the time evolution of the variance of each landmark by a finite set of differential equations, and the other is based on an Expectation-Maximisation algorithm. In the second method, the evaluation of the data likelihood is achieved without registering the landmarks, by applying bridge sampling using a stochastically perturbed version of the large deformation gradient flow algorithm. The method and the estimation algorithms are experimentally validated on synthetic examples and shape data of human corpora callosa
Left atrial trajectory impairment in hypertrophic cardiomyopathy disclosed by geometric morphometrics and parallel transport
The analysis of full Left Atrium (LA) deformation and whole LA deformational trajectory in time has been poorly investigated and, to the best of our knowledge, seldom discussed in patients with Hypertrophic Cardiomyopathy. Therefore, we considered 22 patients with Hypertrophic Cardiomyopathy (HCM) and 46 healthy subjects, investigated them by three-dimensional Speckle Tracking Echocardiography, and studied the derived landmark clouds via Geometric Morphometrics with Parallel Transport. Trajectory shape and trajectory size were different in Controls versus HCM and their classification powers had high AUC (Area Under the Receiving Operator Characteristic Curve) and accuracy. The two trajectories were much different at the transition between LA conduit and booster pump functions. Full shape and deformation analyses with trajectory analysis enabled a straightforward perception of pathophysiological consequences of HCM condition on LA functioning. It might be worthwhile to apply these techniques to look for novel pathophysiological approaches that may better define atrio-ventricular interaction
ROAM: a Rich Object Appearance Model with Application to Rotoscoping
Rotoscoping, the detailed delineation of scene elements through a video shot,
is a painstaking task of tremendous importance in professional post-production
pipelines. While pixel-wise segmentation techniques can help for this task,
professional rotoscoping tools rely on parametric curves that offer the artists
a much better interactive control on the definition, editing and manipulation
of the segments of interest. Sticking to this prevalent rotoscoping paradigm,
we propose a novel framework to capture and track the visual aspect of an
arbitrary object in a scene, given a first closed outline of this object. This
model combines a collection of local foreground/background appearance models
spread along the outline, a global appearance model of the enclosed object and
a set of distinctive foreground landmarks. The structure of this rich
appearance model allows simple initialization, efficient iterative optimization
with exact minimization at each step, and on-line adaptation in videos. We
demonstrate qualitatively and quantitatively the merit of this framework
through comparisons with tools based on either dynamic segmentation with a
closed curve or pixel-wise binary labelling
Morphable Face Models - An Open Framework
In this paper, we present a novel open-source pipeline for face registration
based on Gaussian processes as well as an application to face image analysis.
Non-rigid registration of faces is significant for many applications in
computer vision, such as the construction of 3D Morphable face models (3DMMs).
Gaussian Process Morphable Models (GPMMs) unify a variety of non-rigid
deformation models with B-splines and PCA models as examples. GPMM separate
problem specific requirements from the registration algorithm by incorporating
domain-specific adaptions as a prior model. The novelties of this paper are the
following: (i) We present a strategy and modeling technique for face
registration that considers symmetry, multi-scale and spatially-varying
details. The registration is applied to neutral faces and facial expressions.
(ii) We release an open-source software framework for registration and
model-building, demonstrated on the publicly available BU3D-FE database. The
released pipeline also contains an implementation of an Analysis-by-Synthesis
model adaption of 2D face images, tested on the Multi-PIE and LFW database.
This enables the community to reproduce, evaluate and compare the individual
steps of registration to model-building and 3D/2D model fitting. (iii) Along
with the framework release, we publish a new version of the Basel Face Model
(BFM-2017) with an improved age distribution and an additional facial
expression model
A statistical shape model for deformable surface
This short paper presents a deformable surface registration scheme which is based on the statistical shape
modelling technique. The method consists of two major processing stages, model building and model
fitting. A statistical shape model is first built using a set of training data. Then the model is deformed and
matched to the new data by a modified iterative closest point (ICP) registration process. The proposed
method is tested on real 3-D facial data from BU-3DFE database. It is shown that proposed method can
achieve a reasonable result on surface registration, and can be used for patient position monitoring in
radiation therapy and potentially can be used for monitoring of the radiation therapy progress for head and
neck patients by analysis of facial articulation
View-based modelling of human visual navigation errors
View-based and Cartesian representations provide rival accounts of
visual navigation in humans, and here we explore possible models
for the view-based case. A visual âhomingâ experiment was undertaken
by human participants in immersive virtual reality. The distributions
of end-point errors on the ground plane differed significantly
in shape and extent depending on visual landmark configuration and
relative goal location. A model based on simple visual cues captures
important characteristics of these distributions. Augmenting visual
features to include 3D elements such as stereo and motion parallax
result in a set of models that describe the data accurately, demonstrating
the effectiveness of a view-based approach
Gaussian Process Morphable Models
Statistical shape models (SSMs) represent a class of shapes as a normal
distribution of point variations, whose parameters are estimated from example
shapes. Principal component analysis (PCA) is applied to obtain a
low-dimensional representation of the shape variation in terms of the leading
principal components. In this paper, we propose a generalization of SSMs,
called Gaussian Process Morphable Models (GPMMs). We model the shape variations
with a Gaussian process, which we represent using the leading components of its
Karhunen-Loeve expansion. To compute the expansion, we make use of an
approximation scheme based on the Nystrom method. The resulting model can be
seen as a continuous analogon of an SSM. However, while for SSMs the shape
variation is restricted to the span of the example data, with GPMMs we can
define the shape variation using any Gaussian process. For example, we can
build shape models that correspond to classical spline models, and thus do not
require any example data. Furthermore, Gaussian processes make it possible to
combine different models. For example, an SSM can be extended with a spline
model, to obtain a model that incorporates learned shape characteristics, but
is flexible enough to explain shapes that cannot be represented by the SSM. We
introduce a simple algorithm for fitting a GPMM to a surface or image. This
results in a non-rigid registration approach, whose regularization properties
are defined by a GPMM. We show how we can obtain different registration
schemes,including methods for multi-scale, spatially-varying or hybrid
registration, by constructing an appropriate GPMM. As our approach strictly
separates modelling from the fitting process, this is all achieved without
changes to the fitting algorithm. We show the applicability and versatility of
GPMMs on a clinical use case, where the goal is the model-based segmentation of
3D forearm images
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