Wireless body sensor networks for health-monitoring applications

This is an author-created, un-copyedited version of an article accepted for publication in Physiological Measurement. The publisher is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at http://dx.doi.org/10.1088/0967-3334/29/11/R01

Wireless Power Transfer Techniques for Implantable Medical Devices:A Review

Wireless power transfer (WPT) systems have become increasingly suitable solutions for the electrical powering of advanced multifunctional micro-electronic devices such as those found in current biomedical implants. The design and implementation of high power transfer efficiency WPT systems are, however, challenging. The size of the WPT system, the separation distance between the outside environment and location of the implanted medical device inside the body, the operating frequency and tissue safety due to power dissipation are key parameters to consider in the design of WPT systems. This article provides a systematic review of the wide range of WPT systems that have been investigated over the last two decades to improve overall system performance. The various strategies implemented to transfer wireless power in implantable medical devices (IMDs) were reviewed, which includes capacitive coupling, inductive coupling, magnetic resonance coupling and, more recently, acoustic and optical powering methods. The strengths and limitations of all these techniques are benchmarked against each other and particular emphasis is placed on comparing the implanted receiver size, the WPT distance, power transfer efficiency and tissue safety presented by the resulting systems. Necessary improvements and trends of each WPT techniques are also indicated per specific IMD

Coupled resonator based wireless power transfer for bioelectronics

Implantable and wearable bioelectronics provide the ability to monitor and modulate physiological processes. They represent a promising set of technologies that can provide new treatment for patients or new tools for scientific discovery, such as in long-term studies involving small animals. As these technologies advance, two trends are clear, miniaturization and increased sophistication i.e. multiple channels, wireless bi-directional communication, and responsiveness (closed-loop devices). One primary challenge in realizing miniaturized and sophisticated bioelectronics is powering. Integration and development of wireless power transfer (WPT) technology, however, can overcome this challenge. In this dissertation, I propose the use of coupled resonator WPT for bioelectronics and present a new generalized analysis and optimization methodology, derived from complex microwave bandpass filter synthesis, for maximizing and controlling coupled resonator based WPT performance. This newly developed set of analysis and optimization methods enables system miniaturization while simultaneously achieving the necessary performance to safely power sophisticated bioelectronics. As an application example, a novel coil to coil based coupled resonator arrangement to wirelessly operate eight surface electromyography sensing devices wrapped circumferentially around an able-bodied arm is developed and demonstrated. In addition to standard coil to coil based systems, this dissertation also presents a new form of coupled resonator WPT system built of a large hollow metallic cavity resonator. By leveraging the analysis and optimization methods developed here, I present a new cavity resonator WPT system for long-term experiments involving small rodents for the first time. The cavity resonator based WPT arena exhibits a volume of 60.96 x 60.96 x 30.0 cm3. In comparison to prior state of the art, this cavity resonator system enables nearly continuous wireless operation of a miniature sophisticated device implanted in a freely behaving rodent within the largest space. Finally, I present preliminary work, providing the foundation for future studies, to demonstrate the feasibility of treating segments of the human body as a dielectric waveguide resonator. This creates another form of a coupled resonator system. Preliminary experiments demonstrated optimized coupled resonator wireless energy transfer into human tissue. The WPT performance achieved to an ultra-miniature sized receive coil (2 mm diameter) is presented. Indeed, optimized coupled resonator systems, broadened to include cavity resonator structures and human formed dielectric resonators, can enable the effective use of coupled resonator based WPT technology to power miniaturized and sophisticated bioelectronics

Low power CMOS IC, biosensor and wireless power transfer techniques for wireless sensor network application

The emerging field of wireless sensor network (WSN) is receiving great attention due to the interest in healthcare. Traditional battery-powered devices suffer from large size, weight and secondary replacement surgery after the battery life-time which is often not desired, especially for an implantable application. Thus an energy harvesting method needs to be investigated. In addition to energy harvesting, the sensor network needs to be low power to extend the wireless power transfer distance and meet the regulation on RF power exposed to human tissue (specific absorption ratio). Also, miniature sensor integration is another challenge since most of the commercial sensors have rigid form or have a bulky size. The objective of this thesis is to provide solutions to the aforementioned challenges

Millimeter-Scale and Energy-Efficient RF Wireless System

This dissertation focuses on energy-efficient RF wireless system with millimeter-scale dimension, expanding the potential use cases of millimeter-scale computing devices. It is challenging to develop RF wireless system in such constrained space. First, millimeter-sized antennae are electrically-small, resulting in low antenna efficiency. Second, their energy source is very limited due to the small battery and/or energy harvester. Third, it is required to eliminate most or all off-chip devices to further reduce system dimension. In this dissertation, these challenges are explored and analyzed, and new methods are proposed to solve them. Three prototype RF systems were implemented for demonstration and verification. The first prototype is a 10 cubic-mm inductive-coupled radio system that can be implanted through a syringe, aimed at healthcare applications with constrained space. The second prototype is a 3x3x3 mm far-field 915MHz radio system with 20-meter NLOS range in indoor environment. The third prototype is a low-power BLE transmitter using 3.5x3.5 mm planar loop antenna, enabling millimeter-scale sensors to connect with ubiquitous IoT BLE-compliant devices. The work presented in this dissertation improves use cases of millimeter-scale computers by presenting new methods for improving energy efficiency of wireless radio system with extremely small dimensions. The impact is significant in the age of IoT when everything will be connected in daily life.PHDElectrical EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttps://deepblue.lib.umich.edu/bitstream/2027.42/147686/1/yaoshi_1.pd

Capsule endoscopy system with novel imaging algorithms

Wireless capsule endoscopy (WCE) is a state-of-the-art technology to receive images of human intestine for medical diagnostics. In WCE, the patient ingests a specially designed electronic capsule which has imaging and wireless transmission capabilities inside it. While the capsule travels through the gastrointestinal (GI) tract, it captures images and sends them wirelessly to an outside data logger unit. The data logger stores the image data and then they are transferred to a personal computer (PC) where the images are reconstructed and displayed for diagnosis. The key design challenge in WCE is to reduce the area and power consumption of the capsule while maintaining acceptable image reconstruction. In this research, the unique properties of WCE images are identified by analyzing hundreds of endoscopic images and video frames, and then these properties are used to develop novel and low complexity compression algorithms tailored for capsule endoscopy. The proposed image compressor consists of a new YEF color space converter, lossless prediction coder, customizable chrominance sub-sampler and an efficient Golomb-Rice encoder. The scheme has both lossy and lossless modes and is further customized to work with two lighting modes – conventional white light imaging (WLI) and emerging narrow band imaging (NBI). The average compression ratio achieved using the proposed lossy compression algorithm is 80.4% for WBI and 79.2% for NBI with high reconstruction quality index for both bands. Two surveys have been conducted which show that the reconstructed images have high acceptability among medical imaging doctors and gastroenterologists. The imaging algorithms have been realized in hardware description language (HDL) and their functionalities have been verified in field programmable gate array (FPGA) board. Later it was implemented in a 0.18 μm complementary metal oxide semiconductor (CMOS) technology and the chip was fabricated. Due to the low complexity of the core compressor, it consumes only 43 µW of power and 0.032 mm2 of area. The compressor is designed to work with commercial low-power image sensor that outputs image pixels in raster scan fashion, eliminating the need of significant input buffer memory. To demonstrate the advantage, a prototype of the complete WCE system including an FPGA based electronic capsule, a microcontroller based data logger unit and a Windows based image reconstruction software have been developed. The capsule contains the proposed low complexity image compressor and can generate both lossy and lossless compressed bit-stream. The capsule prototype also supports both white light imaging (WLI) and narrow band imaging (NBI) imaging modes and communicates with the data logger in full duplex fashion, which enables configuring the image size and imaging mode in real time during the examination. The developed data logger is portable and has a high data rate wireless connectivity including Bluetooth, graphical display for real time image viewing with state-of-the-art touch screen technology. The data are logged in micro SD cards and can be transferred to PC or Smartphone using card reader, USB interface, or Bluetooth wireless link. The workstation software can decompress and show the reconstructed images. The images can be navigated, marked, zoomed and can be played as video. Finally, ex-vivo testing of the WCE system has been done in pig's intestine to validate its performance

Antenna Systems

This book offers an up-to-date and comprehensive review of modern antenna systems and their applications in the fields of contemporary wireless systems. It constitutes a useful resource of new material, including stochastic versus ray tracing wireless channel modeling for 5G and V2X applications and implantable devices. Chapters discuss modern metalens antennas in microwaves, terahertz, and optical domain. Moreover, the book presents new material on antenna arrays for 5G massive MIMO beamforming. Finally, it discusses new methods, devices, and technologies to enhance the performance of antenna systems

Study of Dual Band Wearable Antennas Using Commonly Worn Fabric Materials

In recent years, body-centric communication has become one of the most attractive fields of study. The versatile applications of body-centric communication not only being used for health monitoring, but also for real-time communication purposes in special occupations. They are important for supporting a population with increasing life expectancy and increase the probability of survival for the people suffering from chronic illness. For both wearable and implantable form of body-centric communication, characterizing the system electromagnetically is very important. Given the constraints in power, size, weight and conformity, one of the most challenging parts become the designing antenna for such communication systems. Wearable antennas are the most popular option regarding these issues. Wearable antennas are easier and simpler to mount on clothing when they are made of textile materials. In the process of designing a textile antenna, the availability of the fabrics is pivotal to mount on regularly worn clothes. In this report, several designs of a co-planar waveguide microstrip patch antenna are presented. Instead of felt fabric, the antenna was modified using 100% polyester and cotton fabric for the substrate material. A parasitic patch slot was created on the co-planar ground plane to achieve the dual band resonance frequencies at 2.4 GHz and 5.15 GHz. The geometrical modifications of the antennas were described and their performances were analyzed. The antenna achieved resonating frequency with a thinner substrate as the dielectric constant went higher for the fabrics. The design with different fabric materials was first simulated in CST Microwave Studio, then fabricated and measured in a regular environment. They were also mounted on a 3-D printed human body model to analyze the bending effect. The design of the antennas shows satisfactory performance with a good -10dB bandwidth for both the lower and higher desired resonating frequency bandElectrical Engineerin

Communication and energy delivery architectures for personal medical devices

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 219-232).Advances in sensor technologies and integrated electronics are revolutionizing how humans access and receive healthcare. However, many envisioned wearable or implantable systems are not deployable in practice due to high energy consumption and anatomically-limited size constraints, necessitating large form-factors for external devices, or eventual surgical re-implantation procedures for in-vivo applications. Since communication and energy-management sub-systems often dominate the power budgets of personal biomedical devices, this thesis explores alternative usecases, system architectures, and circuit solutions to reduce their energy burden. For wearable applications, a system-on-chip is designed that both communicates and delivers power over an eTextiles network. The transmitter and receiver front-ends are at least an order of magnitude more efficient than conventional body-area networks. For implantable applications, two separate systems are proposed that avoid reimplantation requirements. The first system extracts energy from the endocochlear potential, an electrochemical gradient found naturally within the inner-ear of mammals, in order to power a wireless sensor. Since extractable energy levels are limited, novel sensing, communication, and energy management solutions are proposed that leverage duty-cycling to achieve enabling power consumptions that are at least an order of magnitude lower than previous work. Clinical measurements show the first system demonstrated to sustain itself with a mammalian-generated electrochemical potential operating as the only source of energy into the system. The second system leverages the essentially unlimited number of re-charge cycles offered by ultracapacitors. To ease patient usability, a rapid wireless capacitor charging architecture is proposed that employs a multi-tapped secondary inductive coil to provide charging times that are significantly faster than conventional approaches.by Patrick Philip Mercier.Ph.D