Supervised evaluation of image segmentation and object proposal techniques

This paper tackles the supervised evaluation of image segmentation and object proposal algorithms. It surveys, structures, and deduplicates the measures used to compare both segmentation results and object proposals with a ground truth database; and proposes a new measure: the precision-recall for objects and parts. To compare the quality of these measures, eight state-of-the-art object proposal techniques are analyzed and two quantitative meta-measures involving nine state of the art segmentation methods are presented. The meta-measures consist in assuming some plausible hypotheses about the results and assessing how well each measure reflects these hypotheses. As a conclusion of the performed experiments, this paper proposes the tandem of precision-recall curves for boundaries and for objects-and-parts as the tool of choice for the supervised evaluation of image segmentation. We make the datasets and code of all the measures publicly available.Peer ReviewedPostprint (author's final draft

Pre and Post-hoc Diagnosis and Interpretation of Malignancy from Breast DCE-MRI

We propose a new method for breast cancer screening from DCE-MRI based on a post-hoc approach that is trained using weakly annotated data (i.e., labels are available only at the image level without any lesion delineation). Our proposed post-hoc method automatically diagnosis the whole volume and, for positive cases, it localizes the malignant lesions that led to such diagnosis. Conversely, traditional approaches follow a pre-hoc approach that initially localises suspicious areas that are subsequently classified to establish the breast malignancy -- this approach is trained using strongly annotated data (i.e., it needs a delineation and classification of all lesions in an image). Another goal of this paper is to establish the advantages and disadvantages of both approaches when applied to breast screening from DCE-MRI. Relying on experiments on a breast DCE-MRI dataset that contains scans of 117 patients, our results show that the post-hoc method is more accurate for diagnosing the whole volume per patient, achieving an AUC of 0.91, while the pre-hoc method achieves an AUC of 0.81. However, the performance for localising the malignant lesions remains challenging for the post-hoc method due to the weakly labelled dataset employed during training.Comment: Submitted to Medical Image Analysi

A New Ensemble Learning Framework for 3D Biomedical Image Segmentation

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own strengths and weaknesses, and by unifying them together, one may be able to achieve more accurate results. In this paper, we propose a new ensemble learning framework for 3D biomedical image segmentation that combines the merits of 2D and 3D models. First, we develop a fully convolutional network based meta-learner to learn how to improve the results from 2D and 3D models (base-learners). Then, to minimize over-fitting for our sophisticated meta-learner, we devise a new training method that uses the results of the base-learners as multiple versions of "ground truths". Furthermore, since our new meta-learner training scheme does not depend on manual annotation, it can utilize abundant unlabeled 3D image data to further improve the model. Extensive experiments on two public datasets (the HVSMR 2016 Challenge dataset and the mouse piriform cortex dataset) show that our approach is effective under fully-supervised, semi-supervised, and transductive settings, and attains superior performance over state-of-the-art image segmentation methods.Comment: To appear in AAAI-2019. The first three authors contributed equally to the pape

Automatic annotation for weakly supervised learning of detectors

PhDObject detection in images and action detection in videos are among the most widely studied computer vision problems, with applications in consumer photography, surveillance, and automatic media tagging. Typically, these standard detectors are fully supervised, that is they require a large body of training data where the locations of the objects/actions in images/videos have been manually annotated. With the emergence of digital media, and the rise of high-speed internet, raw images and video are available for little to no cost. However, the manual annotation of object and action locations remains tedious, slow, and expensive. As a result there has been a great interest in training detectors with weak supervision where only the presence or absence of object/action in image/video is needed, not the location. This thesis presents approaches for weakly supervised learning of object/action detectors with a focus on automatically annotating object and action locations in images/videos using only binary weak labels indicating the presence or absence of object/action in images/videos. First, a framework for weakly supervised learning of object detectors in images is presented. In the proposed approach, a variation of multiple instance learning (MIL) technique for automatically annotating object locations in weakly labelled data is presented which, unlike existing approaches, uses inter-class and intra-class cue fusion to obtain the initial annotation. The initial annotation is then used to start an iterative process in which standard object detectors are used to refine the location annotation. Finally, to ensure that the iterative training of detectors do not drift from the object of interest, a scheme for detecting model drift is also presented. Furthermore, unlike most other methods, our weakly supervised approach is evaluated on data without manual pose (object orientation) annotation. Second, an analysis of the initial annotation of objects, using inter-class and intra-class cues, is carried out. From the analysis, a new method based on negative mining (NegMine) is presented for the initial annotation of both object and action data. The NegMine based approach is a much simpler formulation using only inter-class measure and requires no complex combinatorial optimisation but can still meet or outperform existing approaches including the previously pre3 sented inter-intra class cue fusion approach. Furthermore, NegMine can be fused with existing approaches to boost their performance. Finally, the thesis will take a step back and look at the use of generic object detectors as prior knowledge in weakly supervised learning of object detectors. These generic object detectors are typically based on sampling saliency maps that indicate if a pixel belongs to the background or foreground. A new approach to generating saliency maps is presented that, unlike existing approaches, looks beyond the current image of interest and into images similar to the current image. We show that our generic object proposal method can be used by itself to annotate the weakly labelled object data with surprisingly high accuracy