Machine prognostics based on health state estimation using SVM

The ability to accurately predict the remaining useful life of machine components is critical for continuous operations in machines which can also improve productivity and enhance system safety. In condition-based maintenance (CBM), effective diagnostics and prognostics are important aspects of CBM which provide sufficient time for maintenance engineers to schedule a repair and acquire replacement components before the components finally fail. All machine components have certain characteristics of failure patterns and are subjected to degradation processes in real environments. This paper describes a technique for accurate assessment of the remnant life of machines based on prior expert knowledge embedded in closed loop prognostics systems. The technique uses Support Vector Machines (SVM) for classification of faults and evaluation of health for six stages of bearing degradation. To validate the feasibility of the proposed model, several fault historical data from High Pressure Liquefied Natural Gas (LNG) pumps were analysed to obtain their failure patterns. The results obtained were very encouraging and the prediction closely matched the real life particularly at the end of term of the bearings

An Interpretable Deep Hierarchical Semantic Convolutional Neural Network for Lung Nodule Malignancy Classification

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of model interpretability hinders them from being fully understood by target users such as radiologists. In this paper, we present a novel interpretable deep hierarchical semantic convolutional neural network (HSCNN) to predict whether a given pulmonary nodule observed on a computed tomography (CT) scan is malignant. Our network provides two levels of output: 1) low-level radiologist semantic features, and 2) a high-level malignancy prediction score. The low-level semantic outputs quantify the diagnostic features used by radiologists and serve to explain how the model interprets the images in an expert-driven manner. The information from these low-level tasks, along with the representations learned by the convolutional layers, are then combined and used to infer the high-level task of predicting nodule malignancy. This unified architecture is trained by optimizing a global loss function including both low- and high-level tasks, thereby learning all the parameters within a joint framework. Our experimental results using the Lung Image Database Consortium (LIDC) show that the proposed method not only produces interpretable lung cancer predictions but also achieves significantly better results compared to common 3D CNN approaches

Predicting protein-protein interactions as a one-class classification problem

Protein-protein interactions represent a key step in understanding proteins functions. This is due to the fact that proteins usually work in context of other proteins and rarely function alone. Machine learning techniques have been used to predict protein-protein interactions. However, most of these techniques address this problem as a binary classification problem. While it is easy to get a dataset of interacting protein as positive example, there is no experimentally confirmed non-interacting protein to be considered as a negative set. Therefore, in this paper we solve this problem as a one-class classification problem using One-Class SVM (OCSVM). Using only positive examples (interacting protein pairs) for training, the OCSVM achieves accuracy of 80%. These results imply that protein-protein interaction can be predicted using one-class classifier with reliable accuracy