Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

Big Universe, Big Data: Machine Learning and Image Analysis for Astronomy

Astrophysics and cosmology are rich with data. The advent of wide-area digital cameras on large aperture telescopes has led to ever more ambitious surveys of the sky. Data volumes of entire surveys a decade ago can now be acquired in a single night and real-time analysis is often desired. Thus, modern astronomy requires big data know-how, in particular it demands highly efficient machine learning and image analysis algorithms. But scalability is not the only challenge: Astronomy applications touch several current machine learning research questions, such as learning from biased data and dealing with label and measurement noise. We argue that this makes astronomy a great domain for computer science research, as it pushes the boundaries of data analysis. In the following, we will present this exciting application area for data scientists. We will focus on exemplary results, discuss main challenges, and highlight some recent methodological advancements in machine learning and image analysis triggered by astronomical applications

Aerospace Medicine and Biology: a Continuing Bibliography with Indexes (Supplement 328)

This bibliography lists 104 reports, articles and other documents introduced into the NASA Scientific and Technical Information System during September, 1989. Subject coverage includes: aerospace medicine and psychology, life support systems and controlled environments, safety equipment, exobiology and extraterrestrial life, and flight crew behavior and performance

Exploring the Time Domain With Synoptic Sky Surveys

Synoptic sky surveys are becoming the largest data generators in astronomy, and they are opening a new research frontier, that touches essentially every field of astronomy. Opening of the time domain to a systematic exploration will strengthen our understanding of a number of interesting known phenomena, and may lead to the discoveries of as yet unknown ones. We describe some lessons learned over the past decade, and offer some ideas that may guide strategic considerations in planning and execution of the future synoptic sky surveys.Comment: Invited talk, to appear in proc. IAU SYmp. 285, "New Horizons in Time Domain Astronomy", eds. E. Griffin et al., Cambridge Univ. Press (2012). Latex file, 6 pages, style files include