Resource utilisation and direct costs in patients with recently diagnosed fibromyalgia who are offered one of three different interventions in a randomised pragmatic trial

The purpose of this study is to understand the course of costs over a 2-year period in a cohort of recently diagnosed fibromyalgia (FM) patients receiving different treatment strategies. Following the diagnosis, patients were randomly assigned to a multidisciplinary programme (MD), aerobic exercise (AE) or usual care (UC) without being aware of alternative interventions. Time between diagnosis and start of treatment varied between patients. Resource utilisation, health care costs and costs for patients and families were collected through cost diaries. Mixed linear model analyses (MLM) examined the course of costs over time. Linear regression was used to explore predictors of health care costs in the post-intervention period. Two hundred three participants, 90 % women, mean (SD) age 41.7 (9.8) years, were included in the cohort. Intervention costs per patient varied from €864 to 1392 for MD and were €121 for AE. Health care costs (excluding intervention costs) decreased after diagnosis, but before the intervention in each group, and increased again afterwards to the level close to the diagnostic phase. In contrast, patient and family costs slightly increased over time in all groups without initial decrease immediately after diagnosis. Annualised health care costs post-intervention varied between €1872 and 2310 per patient and were predicted by worse functioning and high health care costs at diagnosis. In patients with FM, health care costs decreased following the diagnosis by a rheumatologist. Offering patients a specific intervention after diagnosis incurred substantial costs while having only marginal effects on cost

Wiley Journal Package: UNL Download Activity by Subject

Because the field of librarianship has been reconsidering its relationship to commercial academic publishers and their \u27Big Deal\u27 journal packages, the authors decided to review the University of Nebraska-Lincoln\u27s usage of Wiley\u27s package. In this report, the authors looked into whether UNL\u27s downloads by subject were such that subscribing to a number of hypothetical smaller, subject-specific packages, rather than to the entire Wiley package, might be a viable strategy

Metrics to evaluate research performance in academic institutions: A critique of ERA 2010 as applied in forestry and the indirect H2 index as a possible alternative

Excellence for Research in Australia (ERA) is an attempt by the Australian Research Council to rate Australian universities on a 5-point scale within 180 Fields of Research using metrics and peer evaluation by an evaluation committee. Some of the bibliometric data contributing to this ranking suffer statistical issues associated with skewed distributions. Other data are standardised year-by-year, placing undue emphasis on the most recent publications which may not yet have reliable citation patterns. The bibliometric data offered to the evaluation committees is extensive, but lacks effective syntheses such as the h-index and its variants. The indirect H2 index is objective, can be computed automatically and efficiently, is resistant to manipulation, and a good indicator of impact to assist the ERA evaluation committees and to similar evaluations internationally.Comment: 19 pages, 6 figures, 7 tables, appendice

Environmental sciences research in northern Australia, 2000-2011: a bibliometric analysis within the context of a national research assessment exercise

This paper reports on a bibliometric analysis of environmental sciences research in northern Australia between 2000 and 2011. It draws on publications data for Charles Darwin University (CDU) and James Cook University (JCU) researchers to present a bibliometric profile of the journals in which they publish, the citations to their research outputs, and the key research topics discussed in the publications. Framing this analysis, the study explored the relationship between the two universities’ publications and their ‘fit’ with the environmental sciences field as defined by the Australian research assessment model, Excellence in Research for Australia (ERA). The Scopus database retrieved more records than Web of Science, although only minor differences were seen in the journals in which researchers published most frequently and the most highly cited articles. Strong growth in publications is evident in the 12 year period, but the journals in which the researchers publish most frequently differ from the journals in which the most highly cited articles are published. Many of the articles by CDU and JCU affiliated researchers are published in journals outside of the environmental sciences category as defined by Scopus and Web of Science categories and the ERA, however, the research conducted at each university aligns closely with that institution’s research priorities

Mastectomy with immediate breast reconstruction during "phase 1" COVID-19 emergency: An Italian experience.

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Long-Term Remission of an Aggressive Sebaceous Carcinoma following Chemotherapy

Sebaceous carcinoma (SC) is an uncommon neoplasm manifesting itself either in the eyelid or extraocularly in the head and neck area. Surgery is the standard of care. Irradiation is rarely proposed as monotherapy but is frequently administered as an adjuvant regimen following surgical resection. There is no known strategy concerning chemotherapeutic treatment in highly aggressive recurrent - or metastatic - forms of the disease. Our patient presented with an aggressive SC of the scalp recurring after multiple excisions and local radiotherapy. Chemotherapy with 5-fluorouracil, cisplatin and docetaxel was then initiated; 4 cycles were administered, followed by capecitabine maintenance. Shortly after starting chemotherapy, dermal lesions had completely disappeared and radiological response could be seen. The patient experienced an extended period (>20 months) of complete remission. In this report, we show an excellent response of a highly aggressive SC after a combination of chemotherapy as for head and neck cancers