37 research outputs found
La Salle University Undergraduate Catalog 2010-2011
https://digitalcommons.lasalle.edu/course_catalogs/1184/thumbnail.jp
La Salle University Undergraduate Catalog 2011-2012
https://digitalcommons.lasalle.edu/course_catalogs/1185/thumbnail.jp
La Salle University Undergraduate Catalog 2009-2010
https://digitalcommons.lasalle.edu/course_catalogs/1183/thumbnail.jp
La Salle University Undergraduate Catalog 2012-2013
https://digitalcommons.lasalle.edu/course_catalogs/1195/thumbnail.jp
La Salle University Undergraduate Catalog 2013-2014
https://digitalcommons.lasalle.edu/course_catalogs/1197/thumbnail.jp
La Salle University Undergraduate Catalog 2014-2015
https://digitalcommons.lasalle.edu/course_catalogs/1199/thumbnail.jp
La Salle University Undergraduate Catalog 2015-2016
https://digitalcommons.lasalle.edu/course_catalogs/1201/thumbnail.jp
Tensile relaxation of bonded concrete overlays
Includes abstract.Includes bibliographical references (leaves 131-135).Restrained shrinkage in bonded concrete overlays can cause stress build up, cracking and even debonding. Tensile relaxation is the main mechanism of stress relief in concrete overlays. This results in less possibility of cracking and debonding. The research described in this study presents an analytical method of analysis. This method is based on tests performed to assess tensile relaxation in concretes subjected to restraint. Although this study is limited in scope, it serves as an introduction to the topic and contributes a valuable bank of results obtained. In this study, commercial repair mortar (Sika® Rep LW), 0.45 and 0.65 w/c ratio custom-made mixes were investigated. Uniaxial tensile strength, tensile elastic modulus, shrinkage and tensile relaxation tests were done on dog-bone concrete mortar specimens
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LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics
A topic of growing interest in computational neuroscience is the discovery of fundamental principles underlying global dynamics and the self-organization of the brain. In particular, the notion that the brain operates near criticality has gained considerable support, and recent work has shown that the dynamics of different brain states may be modeled by pairwise maximum entropy Ising models at various distances from a phase transition, i.e., from criticality. Here we aim to characterize two brain states (psychedelics-induced and placebo) as captured by functional magnetic resonance imaging (fMRI), with features derived from the Ising spin model formalism (system temperature, critical point, susceptibility) and from algorithmic complexity. We hypothesized, along the lines of the entropic brain hypothesis, that psychedelics drive brain dynamics into a more disordered state at a higher Ising temperature and increased complexity. We analyze resting state blood-oxygen-level-dependent (BOLD) fMRI data collected in an earlier study from fifteen subjects in a control condition (placebo) and during ingestion of lysergic acid diethylamide (LSD). Working with the automated anatomical labeling (AAL) brain parcellation, we first create “archetype” Ising models representative of the entire dataset (global) and of the data in each condition. Remarkably, we find that such archetypes exhibit a strong correlation with an average structural connectome template obtained from dMRI (r = 0.6). We compare the archetypes from the two conditions and find that the Ising connectivity in the LSD condition is lower than in the placebo one, especially in homotopic links (interhemispheric connectivity), reflecting a significant decrease of homotopic functional connectivity in the LSD condition. The global archetype is then personalized for each individual and condition by adjusting the system temperature. The resulting temperatures are all near but above the critical point of the model in the paramagnetic (disordered) phase. The individualized Ising temperatures are higher in the LSD condition than in the placebo condition (p = 9 × 10−5). Next, we estimate the Lempel-Ziv-Welch (LZW) complexity of the binarized BOLD data and the synthetic data generated with the individualized model using the Metropolis algorithm for each participant and condition. The LZW complexity computed from experimental data reveals a weak statistical relationship with condition (p = 0.04 one-tailed Wilcoxon test) and none with Ising temperature (r(13) = 0.13, p = 0.65), presumably because of the limited length of the BOLD time series. Similarly, we explore complexity using the block decomposition method (BDM), a more advanced method for estimating algorithmic complexity. The BDM complexity of the experimental data displays a significant correlation with Ising temperature (r(13) = 0.56, p = 0.03) and a weak but significant correlation with condition (p = 0.04, one-tailed Wilcoxon test). This study suggests that the effects of LSD increase the complexity of brain dynamics by loosening interhemispheric connectivity—especially homotopic links. In agreement with earlier work using the Ising formalism with BOLD data, we find the brain state in the placebo condition is already above the critical point, with LSD resulting in a shift further away from criticality into a more disordered state