The Effect of Disclosure on Adherence to Antiretroviral Therapy Among Adults Living with HIV in Ethiopia: A Systematic Review and Meta-Analysis.

BACKGROUND: Several factors have been identified as being associated with increased adherence to antiretroviral therapy, including sero-status disclosure; however, studies examining the effect of disclosure on ART adherence in Ethiopia have had inconsistent findings. This systematic review and meta-analysis therefore aims to estimate the pooled effect of disclosure on adherence to ART among adults living with HIV in Ethiopia. METHODS: We performed a systematic search for articles reporting on peer-reviewed, quantitative, English-language observational studies of reporting the association between self sero-status disclosure and good ART adherence in adults living with HIV/AIDS in Ethiopia during published from 2010 to 2015. We searched four electronic databases: PubMed/Medline, the World Health Organization\u27s Hinari portal (which includes the SCOPUS, African Index Medicus, and African Journals Online databases) for studies from December 1, 2017 to January 30, 2018. We also searched university repositories and conference abstracts for unpublished studies. We conducted a meta-analysis for the pooled effect of adherence using a random effects model in Stata version 14 and assessed publication bias using the Egger\u27s test for funnel plot asymmetry. RESULTS: Our search returned in 179 studies, of which seven (3.9%), were eligible and included in the final meta-analysis. The seven included studies were conducted from 2010 to 2015. Our analysis found that disclosure had a significant effect on the adherence to ART in adult patients living with HIV. Patients who disclosed were 1.64 times more likely to have good adherence to ART compared with those who did not (OR: 1.64, 95% CI: 1.11, 2.42). The small number of studies eligible for review and differences in study definitions of adherence and disclosure were the main limitations of this study. CONCLUSION: This review found a statistically significant positive effect of disclosure status on the adherence to ART in adult patients living with HIV in Ethiopia. This suggests that Ethiopia\u27s national treatment and prevention programs should redouble efforts to encourage self-disclosure among people living with HIV/AIDS. Encouraging supportive social environments for disclosure, and promoting partner notification and partner disclosure support initiatives might be particularly helpful in this regard

Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora: The 2015 Update

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Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the diaspora: The 2016 update

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Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora: The 2013 Update

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Adherence to Antiretroviral Treatment among Adult People Living with HIV/AIDS Attending Highly Active Antiretroviral Therapy at Adare Hospital, Southern Ethiopia

AbstractBackground: Adherence to antiretroviral therapy (ART) has paramount advantages for programmatic success, including its good treatment outcomes and reduced risk of resistant viral strains transmission to the general population. There is limited evidence on the magnitude and associated factors of adherence to ART among adult PLWHA attending highly active ART (HAART) at Adare General Hospital, Southern Ethiopia.Objective: This study aimed to determine the magnitude and associated factors of adherence to ART among adult PLWHA attending (HAART) at Adare General Hospital, Southern Ethiopia.Methods: A hospital-based cross-sectional study was conducted from January 01/2018 to February 30/2018 at Adare Hospital. The participants were 370 adult people living with HIV/AIDS taking ART and who were selected by systematic random sampling technique. The data were collected by trained health professionals using a pre-tested interviewer-administered structured questionnaire. The data collected was entered into a computer and analysed using SPSS version 19. Descriptive statistics and multiple logistic regressions were applied. The significance level of association was considered at p-value <0.05.Results: The magnitude of retrospectively self-reported combined adherence (measured by dose, schedule and dietary instructions) to ART in the past seven days before the interview was 80.3%. In multivariate analysis, Sidaamu Afoo language (AOR=0.5, 95%CI: 0.21-0.99), monthly income <1,000 Ethiopian Birr (AOR=0.08; 95%CI: 0.03-0.26), not disclosing HIV status to others (AOR=0.18; 95%CI: 0.07-0.50), taking ART pills comfortably while others looking (AOR=6.0; 95%CI: 2.54-13.91) and no utilisation of reminders (AOR=0.08; 95%CI: 0.03-0.21) were factors significantly associated with combined adherence. Forgetfulness and not wanting to take ART while others are looking were major reasons to miss pills.Conclusion: Adherence to ART among adult PLWHA attending HAART at Adare Hospital was suboptimal, but still comparable with that of resource-limited settings. To maximise treatment success, considering emphasised translation to Sidaamu Afoo language, encouraging patients to be involved in any income-generating system and to reveal their HIV status for others is helpful. [Ethiop. J. Health Dev. 2021; 35(2):105-115]Keywords: Adherence, Adults, ART, HIV/AIDS, Sidaama, Ethiopi

Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora: The 2011 Update

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Bibliography of the Literatures on Tuberculosis, TB/HIV and MDRTB in Ethiopia from 2001 – 2017

Ethiopia is among the thirty-high tuberculosis (TB) burden countries with multidrug resistant tuberculosis (MDR-TB) and Tuberculosis/Human Immunodeficiency Virus (TB/HIV). Given the public health importance of the problem, it is apparent that probing the work done in this regard is essential to mitigate the problem and thus we reviewed research repositories and compile directories of researches in Ethiopia from Jan 1, 2001 to Dec 30, 2017 in order to avail evidence-based information to stakeholders and beneficiaries intervening the problem in the country. The evidences generated in this bibliography are through different databases and websites using key terms. A range of different published and unpublished literatures (journal articles, conference presentations, reports/manual/book, and graduate theses or dissertations) on TB, MDR-TB, extensively drug resistant TB (XDR-TB), or TB/HIV are presented. We presented literatures by four themes (Biomedical and clinical researches, epidemiological researches, operational or implementation researches, and health systems researches). A total of 1571 researches and reports were accessed through the above search engines and revealed 635 epidemiological researches followed by 538 clinical or biomedical researches, 257 operational or implementation research, and 141 health systems research. Interestingly, up to 2008 clinical or biomedical researchers were the leading researches and from 2009 onwards, epidemiological researches held the largest constituency. In conclusion, TB or TB/HIV and MDR-TB literatures in Ethiopia have substantially increased over years. Referred journal publications took theleading source and epidemiologic studies were the commonest one. We suggest the need to focus on operational or implementation and health system researches to plummet the disease spreading, drug resistance and impact. We also recommend a regular update of the bibliography every 3 to 4 years with annotations

Factors Influencing Adherence to Antiretroviral Therapy (ART) among Adolescents Living with Human Immunodeficiency virus (HIV) in Rwanda

Background HIV continues to be an important public health concern among adolescents. To reduce the high rate of mortality and improve the quality of life among people with HIV, WHO guidelines emphasize the early initiation of ART drugs in HIV-infected persons regardless of their CD4 count and clinical status. However, adherence to ART remains low in adolescents between 10 to 19 years from low and middle-income countries (LMICs). Objective To determine the factors influencing adherence to ART among adolescents with HIV in Rwanda. Method A cross-sectional design using proportional stratified random sampling to select 166 adolescents was conducted. Data were analyzed using descriptive and inferential statistics with a p-value <0.05 and a CI of 95%. Results The overall adherence to ARTs was 38%. Assistance of clinical staff in taking medication (p<0.001) and the help of parents in taking medication (p<0.001) positively influenced adherence to ART. Insufficient health care providers, forgetfulness (p=0.009), and dosage too complex (p=0.044) negatively influenced adherence to ART. Conclusion Factors such as someone reminding adolescents to take medication, non-stigmatization, and absence of side effects were positively associated with ART adherence. On the other hand, forgetfulness, complex dosage, being isolated and inadequate education about medications negatively affect adherence to ARTs. There is a need to set strategies to increase adherence to ARTs, including expert clients and trustable guardians in care provision. All adolescents should receive adequate counselling and health education before the initiation of ARTs. Rwanda J Med Health Sci 2022;5(3):251-26

Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora: The 2008 Update

This is the sixth update of the bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora, which was originally published in this journal in 2003. That bibliography covered published and unpublished work on HIV/AIDS and related health conditions (e.g., other sexually transmitted infections, tuberculosis) for the period 1972 to 2002. Five subsequent updates werepublished in 2004, 2005, 2006, 2007 and 2008. The present update extends the bibliography to cover references not listed in previous updates and those recent publications or presentations that appeared in 2008

Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora: The 2006 Update

No Abstract. The Ethiopian Journal of Health Development Vol. 21 (1) 2007: pp. 70-9