Online self-repair of FIR filters

Chip-level failure detection has been a target of research for some time, but today's very deep-submicron technology is forcing such research to move beyond detection. Repair, especially self-repair, has become very important for containing the susceptibility of today's chips. This article introduces a self-repair-solution for the digital FIR filter, one of the key blocks used in DSPs

Accelerating vaccine development and deployment: report of a Royal Society satellite meeting.

The Royal Society convened a meeting on the 17th and 18th November 2010 to review the current ways in which vaccines are developed and deployed, and to make recommendations as to how each of these processes might be accelerated. The meeting brought together academics, industry representatives, research sponsors, regulators, government advisors and representatives of international public health agencies from a broad geographical background. Discussions were held under Chatham House rules. High-throughput screening of new vaccine antigens and candidates was seen as a driving force for vaccine discovery. Multi-stakeholder, small-scale manufacturing facilities capable of rapid production of clinical grade vaccines are currently too few and need to be expanded. In both the human and veterinary areas, there is a need for tiered regulatory standards, differentially tailored for experimental and commercial vaccines, to allow accelerated vaccine efficacy testing. Improved cross-fertilization of knowledge between industry and academia, and between human and veterinary vaccine developers, could lead to more rapid application of promising approaches and technologies to new product development. Identification of best-practices and development of checklists for product development plans and implementation programmes were seen as low-cost opportunities to shorten the timeline for vaccine progression from the laboratory bench to the people who need it

Laboratory and on-site tests for rapid runway repair

The attention to rapid pavement repair has grown fast in recent decades: this topic is strategic for the airport management process for civil purposes and peacekeeping missions. This work presents the results of laboratory and on-site tests for rapid runway repair, in order to analyse and compare technical and mechanical performances of 12 different materials currently used in airport. The study focuses on site repairs, a technique adopted most frequently than repairs with modular elements. After describing mechanical and physical properties of the examined materials (2 bituminous emulsions, 5 cement mortars, 4 cold bituminous mixtures and 1 expanding resin), the study presents the results of carried out mechanical tests. The results demonstrate that the best performing material is a one-component fast setting and hardening cement mortar with graded aggregates. This material allows the runway reopening 6 h after the work. A cold bituminous mixture (bicomponent premixed cold asphalt with water as catalyst) and the ordinary cement concrete allow the reopening to traffic after 18 h, but both ensure a lower service life (1000 coverages) than the cement mortar (10,000 coverages). The obtained results include important information both laboratory level and field, and they could be used by airport management bodies and road agencies when scheduling and evaluating pavement repairs

Distributed Resources Shift Paradigms on Power System Design, Planning, and Operation: An Application of the GAP Model

Power systems have evolved following a century-old paradigm of planning and operating a grid based on large central generation plants connected to load centers through a transmission grid and distribution lines with radial flows. This paradigm is being challenged by the development and diffusion of modular generation and storage technologies. We use a novel approach to assess the sequencing and pacing of centralized, distributed, and off-grid electrification strategies by developing and employing the grid and access planning (GAP) model. GAP is a capacity expansion model to jointly assess operation and investment in utility-scale generation, transmission, distribution, and demand-side resources. This paper conceptually studies the investment and operation decisions for a power system with and without distributed resources. Contrary to the current practice, we find hybrid systems that pair grid connections with distributed energy resources (DERs) are the preferred mode of electricity supply for greenfield expansion under conservative reductions in photovoltaic panel (PV) and energy storage prices. We also find that when distributed PV and storage are employed in power system expansion, there are savings of 15%-20% mostly in capital deferment and reduced diesel use. Results show that enhanced financing mechanisms for DER PV and storage could enable 50%-60% of additional deployment and save 15 /MWh in system costs. These results have important implications to reform current utility business models in developed power systems and to guide the development of electrification strategies in underdeveloped grids

Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals

Chemical manufacturing is often done at large facilities that require a sizable capital investment and then produce key compounds for a finite period. We present an approach to the manufacturing of fine chemicals and pharmaceuticals in a self-contained plastic reactionware device. The device was designed and constructed by using a chemical to computer-automated design (ChemCAD) approach that enables the translation of traditional bench-scale synthesis into a platform-independent digital code. This in turn guides production of a three-dimensional printed device that encloses the entire synthetic route internally via simple operations. We demonstrate the approach for the γ-aminobutyric acid receptor agonist, (±)-baclofen, establishing a concept that paves the way for the local manufacture of drugs outside of specialist facilities

Technologies for 3D Heterogeneous Integration

3D-Integration is a promising technology towards higher interconnect densities and shorter wiring lengths between multiple chip stacks, thus achieving a very high performance level combined with low power consumption. This technology also offers the possibility to build up systems with high complexity just by combining devices of different technologies. For ultra thin silicon is the base of this integration technology, the fundamental processing steps will be described, as well as appropriate handling concepts. Three main concepts for 3D integration have been developed at IZM. The approach with the greatest flexibility called Inter Chip Via - Solid Liquid Interdiffusion (ICV-SLID) is introduced. This is a chip-to-wafer stacking technology which combines the advantages of the Inter Chip Via (ICV) process and the solid-liquid-interdiffusion technique (SLID) of copper and tin. The fully modular ICV-SLID concept allows the formation of multiple device stacks. A test chip was designed and the total process sequence of the ICV-SLID technology for the realization of a three-layer chip-to-wafer stack was demonstrated. The proposed wafer-level 3D integration concept has the potential for low cost fabrication of multi-layer high-performance 3D-SoCs and is well suited as a replacement for embedded technologies based on monolithic integration. To address yield issues a wafer-level chip-scale handling is presented as well, to select known-good dies and work on them with wafer-level process sequences before joining them to integrated stacks.Comment: Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/handle/2042/16838

A new wireless underground network system for continuous monitoring of soil water contents

A new stand-alone wireless embedded network system has been developed recently for continuous monitoring of soil water contents at multiple depths. This paper presents information on the technical aspects of the system, including the applied sensor technology, the wireless communication protocols, the gateway station for data collection, and data transfer to an end user Web page for disseminating results to targeted audiences. Results from the first test of the network system are presented and discussed, including lessons learned so far and actions to be undertaken in the near future to improve and enhance the operability of this innovative measurement approac