Characterization of path loss and absorption for a wireless radio frequency link between an in-body endoscopy capsule and a receiver outside the body

Physical-layer characterization is important for design of in-to-out body communication for wireless body area networks (WBANs). This paper numerically investigates the path loss and absorption of an in-to-out body radio frequency (RF) wireless link between an endoscopy capsule and a receiver outside the body using a 3D electromagnetic solver. A spiral antenna in the endoscopy capsule is tuned to operate in the Medical Implant Communication Service (MICS) band at 402 MHz, accounting for the properties of the human body. The influence of misalignment, rotation of the capsule, and three different human models are investigated. Semi-empirical path loss models for various homogeneous tissues and 3D realistic human body models are provided for manufacturers to evaluate the performance of in-body to out-body WBAN systems. The specific absorption rate (SAR) in homogeneous and heterogeneous body models is characterized and compliance is investigated

In-body path loss models for implants in heterogeneous human tissues using implantable slot dipole conformal flexible antennas

A wireless body area network (WBAN) consists of a wireless network with devices placed close to, attached on, or implanted into the human body. Wireless communication within a human body experiences loss in the form of attenuation and absorption. A path loss model is necessary to account for these losses. In this article, path loss is studied in the heterogeneous anatomical model of a 6-year male child from the Virtual Family using an implantable slot dipole conformal flexible antenna and an in-body path loss model is proposed at 2.45 GHz with application to implants in a human body. The model is based on 3D electromagnetic simulations and is compared to models in a homogeneous muscle tissue medium

Improved reception of in-body signals by means of a wearable multi-antenna system

High data-rate wireless communication for in-body human implants is mainly performed in the 402-405 MHz Medical Implant Communication System band and the 2.45 GHz Industrial, Scientific and Medical band. The latter band offers larger bandwidth, enabling high-resolution live video transmission. Although in-body signal attenuation is larger, at least 29 dB more power may be transmitted in this band and the antenna efficiency for compact antennas at 2.45 GHz is also up to 10 times higher. Moreover, at the receive side, one can exploit the large surface provided by a garment by deploying multiple compact highly efficient wearable antennas, capturing the signals transmitted by the implant directly at the body surface, yielding stronger signals and reducing interference. In this paper, we implement a reliable 3.5 Mbps wearable textile multi-antenna system suitable for integration into a jacket worn by a patient, and evaluate its potential to improve the In-to-Out Body wireless link reliability by means of spatial receive diversity in a standardized measurement setup. We derive the optimal distribution and the minimum number of on-body antennas required to ensure signal levels that are large enough for real-time wireless endoscopy-capsule applications, at varying positions and orientations of the implant in the human body

Wireless capsule gastrointestinal endoscopy: direction of arrival estimation based localization survey

One of the significant challenges in Capsule Endoscopy (CE) is to precisely determine the pathologies location. The localization process is primarily estimated using the received signal strength from sensors in the capsule system through its movement in the gastrointestinal (GI) tract. Consequently, the wireless capsule endoscope (WCE) system requires improvement to handle the lack of the capsule instantaneous localization information and to solve the relatively low transmission data rate challenges. Furthermore, the association between the capsule’s transmitter position, capsule location, signal reduction and the capsule direction should be assessed. These measurements deliver significant information for the instantaneous capsule localization systems based on TOA (time of arrival) approach, PDOA (phase difference of arrival), RSS (received signal strength), electromagnetic, DOA (direction of arrival) and video tracking approaches are developed to locate the WCE precisely. The current article introduces the acquisition concept of the GI medical images using the endoscopy with a comprehensive description of the endoscopy system components. Capsule localization and tracking are considered to be the most important features of the WCE system, thus the current article emphasizes the most common localization systems generally, highlighting the DOA-based localization systems and discusses the required significant research challenges to be addressed

Analysis of the Localization Error for Capsule Endoscopy Applications at UWB Frequencies

Localization for Wireless Capsule Endoscopy (WCE) in the Ultra-Wideband frequency band is a very active field of investigation due to its potential advantages in future endoscopy applications. Received Signal Strength (RSS) based localization is commonly preferred due to its simplicity. Previous studies on Ultra-Wideband (UWB) RSS-based localization showed that the localization accuracy depends on the average ranging error related to the selected combination of receivers, which not always is the one experiencing the highest level of received power. In this paper the tendency of the localization error is further investigated through supplementary software simulations and previously conducted laboratory measurements. Two-dimensional (2D) and three-dimensional (3D) positioning are performed and the trend of the localization error compared in both cases. Results shows that the distribution of the selected path loss values, corresponding to the receivers used for localization, around the in-body position to estimate also affects the localization accuracy.This work was supported by the H2020:MSCA:ITN program for the “Wireless In-body Environment Communication- WiBEC” project under the grant agreement no. 675353. This work was also supported by the European Union’s H2020:MSCA:ITN program for the ”mmWave Communications in the Built Environments - WaveComBE” project under the grant agreement no. 766231.Barbi, M.; Pérez-Simbor, S.; Garcia-Pardo, C.; Cardona Marcet, N. (2019). Analysis of the Localization Error for Capsule Endoscopy Applications at UWB Frequencies. IEEE. https://doi.org/10.1109/ISMICT.2019.8743813

Localization for capsule endoscopy at UWB frequencies using an experimental multilayer phantom

[EN] Localization inside the human body using ultrawideband (UWB) wireless technology is gaining importance in several medical applications such as capsule endoscopy. Performance analysis of RF based localization techniques are mainly conducted through simulations using numerical human models or through experimental measurements using homogeneous phantoms. One of the most common implemented RF localization approaches uses the received signal strength (RSS). However, to the best of our knowledge, no experimental measurements employing multilayer phantoms are currently available in literature. This paper investigates the performance of RSS-based technique for two-dimensional (2D) localization by employing a two-layer experimental phantom-based setup. Preliminary results on the estimation of the in-body antenna coordinates show that RSS-based method can achieve a location accuracy on average of 0.5-1 cm within a certain range of distances between in-body and on-body antenna.This work was supported by the European Union’s H2020:MSCA:ITN program for the ”Wireless In-body Environment Communication- WiBEC” project under the grant agreement no. 675353. This work was also funded by the Programa de Ayudas de Investigación y Desarrollo (PAID-01-16) from Universitat Politècnica de València and by the Ministerio de Economía y Competitividad, Spain (TEC2014-60258-C2-1-R), by the European FEDER funds.Barbi, M.; Pérez Simbor, S.; García Pardo, C.; Andreu Estellés, C.; Cardona Marcet, N. (2018). Localization for capsule endoscopy at UWB frequencies using an experimental multilayer phantom. Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/WCNCW.2018.8369015

In situ characterization of two wireless transmission schemes for ingestible capsules

We report the experimental in situ characterization of 30-40 MHz and 868 MHz wireless transmission schemes for ingestible capsules, in porcine carcasses. This includes a detailed study of the performance of a magnetically coupled near-field very high-frequency (VHF) transmission scheme that requires only one eighth of the volume and one quarter of the power consumption of existing 868-MHz solutions. Our in situ measurements tested the performance of four different capsules specially constructed for this study (two variants of each transmission scheme), in two scenarios. One mimicked the performance of a body-worn receiving coil, while the other allowed the characterization of the direction-dependent signal attenuation due to losses in the surrounding tissue. We found that the magnetically coupled near-field VHF telemetry scheme presents an attractive option for future, miniturized ingestible capsules for medical applications

Use of a 3-D Wireless Power Transfer Technique as a Method for Capsule Localization

Capsule endoscopy has been heralded as a technological milestone in the diagnosis and therapeutics of gastrointestinal (GI) pathologies. The location and position of the capsule within the GI tract are important information for subsequent surgical intervention or local drug delivery. Accurate information of capsule location is therefore required during endoscopy. Although radio frequency (RF)-based, magnetic tracking and video localization have been investigated in the past, the complexity of those systems and potential inaccuracy in the localization data necessitate the scope for further research. This article proposes the dual use of a wireless power transfer (WPT) configuration as a method to enable the determination of the location of an endoscopic capsule. Measurements conducted on a homogeneous agar-based liquid phantom predict a maximum error of 12% between the calculated and measured trajectories of the capsule in a working volume of 100 mm $\times 100$ mm $\times 100$ mm