4 research outputs found
Improvement of peptide identification with considering the abundance of mRNA and peptide
Scripts used for data analysis in this study. (DOCX 35Â kb
Proteomic Contributions to Medicinal Plant Research: From Plant Metabolism to Pharmacological Action
Herbal medicine is a clinical practice of utilizing medicinal plant derivatives for therapeutic purposes. It has an enduring history worldwide and plays a significant role in the fight against various diseases. Herbal drug combinations often exhibit synergistic therapeutic action compared with single-constituent dosage, and can also enhance the cytotoxicity induced by chemotherapeutic drugs. To explore the mechanism underlying the pharmacological action of herbs, proteomic approaches have been applied to the physiology of medicinal plants and its effects on animals. This review article focuses on the existing proteomics-based medicinal plant research and discusses the following topics: (i) plant metabolic pathways that synthesize an array of bioactive compounds; (ii) pharmacological action of plants tested using in vivo and in vitro studies; and (iii) the application of proteomic approaches to indigenous plants with scarce sequence information. The accumulation of proteomic information in a biological or medicinal context may help in formulating the effective use of medicinal plants
Additional file 3: Figure S1. of Improvement of peptide identification with considering the abundance of mRNA and peptide
The weights of features for (A) Jurcat cell line and (B) mouse liver datasets. (DOCX 140Â kb