Meaningful measures for individuals' realities: evidence from the JUBILEE project

Reality differs according to the individual's perception : this is a statement of the obvious. How to deliver appropriate library and information services to fulfil those individuals' requirements is not obvious. Measures of success are needed to form the basis of service planning.These measures must be meaningful for individuals, both users and managers, if the goal of designing and delivering library and information services to meet individuals' realities is to be realised. Contexts are changing for individuals: the fast developing world of electronic information services (EIS) provides individuals with new opportunities and new threats. It is against this background that the JUBILEE project was launched.This paper will use evidence from JUBILEE to present the issues underlying the development of an evaluation toolkit for managers of EIS, which will take into account differences between individuals, between disciplines, and between institutions

Champagne training on a beer budget

[Abstract]: When confronted by rapidly escalating costs for End User Computing (EUC) training and support, the Gold Coast City Council (GCCC) - the local government authority for Australia’s premier tourist destination - took a proactive stance by adopting a low-cost strategy. This strategy has now been in place for about six years and, as shown in this case study, is reaping rewards in terms of productivity increases and technology diffusion. After identifying an appropriate theoretical perspective for the study, this paper describes the EUC training approach taken at GCCC, and investigates its impact on the productivity of the 1500 person workforce. Both the trainees and the trainers were surveyed to evaluate fully this low-cost strategy. Related social issues of empowering the stakeholders are examined and recommendations are made to ensure that this approach will continue to provide champagne training on a beer budget

High-throughput Binding Affinity Calculations at Extreme Scales

Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily selected during treatment. Key to overcoming this challenge is an understanding of the molecular determinants of drug binding. Using multi-stage pipelines of molecular simulations we can gain insights into the binding free energy and the residence time of a ligand, which can inform both stratified and personal treatment regimes and drug development. To support the scalable, adaptive and automated calculation of the binding free energy on high-performance computing resources, we introduce the High- throughput Binding Affinity Calculator (HTBAC). HTBAC uses a building block approach in order to attain both workflow flexibility and performance. We demonstrate close to perfect weak scaling to hundreds of concurrent multi-stage binding affinity calculation pipelines. This permits a rapid time-to-solution that is essentially invariant of the calculation protocol, size of candidate ligands and number of ensemble simulations. As such, HTBAC advances the state of the art of binding affinity calculations and protocols

Risks of user-development application in small business

This paper discusses the risks of developing computerised business applications by end-users particularly in the small business environment. As today’s end-users are becoming more and more sophisticated, coupled with the proliferation of Information Technology (IT) that has brought the computerisation of business activities within reach of many small firms, understanding the benefits and risks of user-developed applications would contribute towards the small firm’s effectiveness in IT adoption. This is particularly relevant in today’s managing business where businesses, including the small firms, in a volatile environment will have to compete not only locally but also globally,and IT is seen to be an enabler that can help small firms to increase their competitiveness. Relevant literature on the benefits and risks of user-developed applications were sought and summarised in this paper. Findings were also based on a case study investigation of small firms with no formal IT function where observations were made on the end-user developers who were given the responsibility to develop the firm’s computerised applications. Whilst the benefits have been enormously highlighted and at times overshadowed the risks, due attention is given to examining the risks so as to provide a more balanced report and a precautionary measure for end-user developers. Risks were categorised according to organisational and individual risks following the application development stages of planning, analysis, design and implementation

Technical considerations towards mobile user QoE enhancement via Cloud interaction

This paper discusses technical considerations of a Cloud infrastructure which interacts with mobile devices in order to migrate part of the computational overhead from the mobile device to the Cloud. The aim of the interaction between the mobile device and the Cloud is the enhancement of parameters that affect the Quality of Experience (QoE) of the mobile end user through the offloading of computational aspects of demanding applications. This paper shows that mobile user’s QoE can be potentially enhanced by offloading computational tasks to the Cloud which incorporates a predictive context-aware mechanism to schedule delivery of content to the mobile end-user using a low-cost interaction model between the Cloud and the mobile user. With respect to the proposed enhancements, both the technical considerations of the cloud infrastructure are examined, as well as the interaction between the mobile device and the Cloud