3 research outputs found

    Shape and topology optimization of enzymatic microreactors

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    Genetic and random search methods in optimal shape design problems

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    We describe the application of two global optimization methods, namely of genetic and random search type algorithms in shape optimization. When the so-called fictitious domain approaches are used for the numerical realization of state problems, the resulting minimized function is non-differentiable and stair-wise, in general. Such complicated behaviour excludes the use of classical local methods. Specific modifications of the above-mentioned global methods for our class of problems are described. Numerical results of several model examples computed by different variants of genetic and random search type algorithms are discussed
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